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Tetracaine

Generic Name
Tetracaine
Brand Names
Ametop, Cetacaine, Kovanaze, One Touch Reformulated Apr 2009, Pliaglis, Synera, Zap
Drug Type
Small Molecule
Chemical Formula
C15H24N2O2
CAS Number
94-24-6
Unique Ingredient Identifier
0619F35CGV
Background

Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.

Indication

Ophthalmic tetracaine is indicated for the for procedures requiring a rapid and short- acting topical ophthalmic anesthetic.

The combination lidocaine and tetracaine patch is indicated for local dermal analgesia for superficial dermatological procedures and superficial venous access. The combination lidocaine and tetracaine cream is intended to provide topical local analgesia for superficial dermatological procedures.

Associated Conditions
Dermabrasion, Haemorrhoids, Insect Bites, Rash caused by poison ivy, Sunburn, Minor burns
Associated Therapies
Local Anaesthesia therapy, Local Anesthesia of the Skin

Efficacy and Safety of Synera in Osteoarthritis Pain

Phase 1
Completed
Conditions
Knee Osteoarthritis
Interventions
Drug: Inactive patch
First Posted Date
2012-07-31
Last Posted Date
2015-05-12
Lead Sponsor
Thomas J. Schnitzer
Target Recruit Count
40
Registration Number
NCT01654302
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

Pharmacokinetic Study of Synera in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2012-05-21
Last Posted Date
2012-10-17
Lead Sponsor
ZARS Pharma Inc.
Target Recruit Count
12
Registration Number
NCT01602757
Locations
🇺🇸

Cetero Research, Fargo, North Dakota, United States

Pain Patch Versus Injections in the Treatment of Pain Associated With Shoulder Impingement Syndrome

First Posted Date
2012-03-05
Last Posted Date
2012-03-06
Lead Sponsor
Injury Care Medical Center
Target Recruit Count
60
Registration Number
NCT01544283
Locations
🇺🇸

Injury Care Medical Center, Boise, Idaho, United States

Study to Evaluate the Efficacy of the Synera Patch Compared to Naproxen Sodium for Epicondylitis of the Elbow

Phase 4
Completed
Conditions
Epicondylitis of the Elbow
Interventions
First Posted Date
2012-02-02
Last Posted Date
2014-03-05
Lead Sponsor
International Clinical Research Institute
Target Recruit Count
78
Registration Number
NCT01525043
Locations
🇺🇸

International Clinical Research Institute, Overland Park, Kansas, United States

Tetracaine Versus Lidocaine Gel for Anesthetic Effect and Comfort in Patients Undergoing LASIK

Phase 4
Terminated
Conditions
Pain
Interventions
First Posted Date
2011-06-28
Last Posted Date
2017-08-11
Lead Sponsor
University of Miami
Target Recruit Count
11
Registration Number
NCT01383200
Locations
🇺🇸

Bascom Palmer Eye Institute, Miami, Florida, United States

Dose-Escalation Safety and Pharmacokinetic Study of K305

Phase 2
Completed
Conditions
Anesthesia
Interventions
First Posted Date
2011-02-25
Last Posted Date
2017-08-31
Lead Sponsor
St. Renatus, LLC
Target Recruit Count
12
Registration Number
NCT01304316
Locations
🇺🇸

University of Pennsylvania, School of Dental Medicine, Philadelphia, Pennsylvania, United States

Intravitreal Injection Anesthesia - Comparison of Different Topical Agents

Not Applicable
Completed
Conditions
Age-Related Macular Degeneration (AMD)
Interventions
First Posted Date
2010-10-20
Last Posted Date
2012-04-19
Lead Sponsor
Lawson Health Research Institute
Target Recruit Count
92
Registration Number
NCT01224847
Locations
🇨🇦

Ivey Eye Institute, London, Ontario, Canada

Comparison of Synera Patch Versus LMX-4 Cream Versus Placebo Patch for Pain Reduction During Venipuncture in Children

Phase 2
Completed
Conditions
Venipuncture
Pain
Anesthetics, Local
Interventions
Drug: LMX 4 Cream
Drug: Placebo Patch
First Posted Date
2010-05-04
Last Posted Date
2014-02-04
Lead Sponsor
Carol Morreale
Target Recruit Count
150
Registration Number
NCT01115062
Locations
🇺🇸

Women and Children Hospital, Charleston, West Virginia, United States

Tetracaine Combined Spinal Epidural (CSE) Versus Bupivacaine CSE

Phase 4
Terminated
Conditions
Labor Pain
Interventions
First Posted Date
2009-11-01
Last Posted Date
2017-11-08
Lead Sponsor
Wake Forest University
Target Recruit Count
46
Registration Number
NCT01005459
Locations
🇺🇸

Forsyth Medical Center- OB Anesthesia dept, Winston-Salem, North Carolina, United States

Open-Label Study Evaluating Synera® in the Treatment of Patients With Carpal Tunnel Syndrome

Phase 2
Completed
Conditions
Carpal Tunnel Syndrome
Interventions
First Posted Date
2009-10-07
Last Posted Date
2012-03-16
Lead Sponsor
ZARS Pharma Inc.
Target Recruit Count
24
Registration Number
NCT00991068
Locations
🇺🇸

International Clinical Research Institute, Overland Park, Kansas, United States

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