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Enfuvirtide

Generic Name
Enfuvirtide
Brand Names
Fuzeon
Drug Type
Biotech
Chemical Formula
-
CAS Number
159519-65-0
Unique Ingredient Identifier
19OWO1T3ZE
Background

Enfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake. The first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 fusion with CD4 cells.

Indication

Enfuvirtide is an antiretroviral drug used in combination therapy for the treatment of HIV-1/AIDS.

Associated Conditions
Human Immunodeficiency Virus Type 1 (HIV-1)
Associated Therapies
-

Study of a New Anti-HIV Drug, T-20, in HIV-Infected Children

Phase 1
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
24
Registration Number
NCT00001118
Locations
🇺🇸

Long Beach Memorial (Pediatric), Long Beach, California, United States

🇺🇸

Univ of Florida Health Science Ctr / Pediatrics, Jacksonville, Florida, United States

🇺🇸

Harlem Hosp Ctr, New York, New York, United States

and more 22 locations

HIV Maintenance Therapy With T-20 During HAART Interruption

Phase 2
Completed
Conditions
HIV Infection
First Posted Date
2001-04-02
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
10
Registration Number
NCT00013884
Locations
🇺🇸

National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, United States

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