Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Comparison of Recovery Profiles Among Propofol, Remimazolam, and Dexmedetomidine After Intraoperative Sedation
- Conditions
- Interventions
- First Posted Date
- 2023-01-18
- Last Posted Date
- 2024-01-31
- Lead Sponsor
- Asan Medical Center
- Target Recruit Count
- 120
- Registration Number
- NCT05688345
- Locations
- 🇰🇷
Asan Medical Center, Seoul, Korea, Republic of
Effect of Sedative and Anxiolytic Premedication on Children Experience After General Anesthesia
- First Posted Date
- 2023-01-12
- Last Posted Date
- 2024-12-16
- Lead Sponsor
- University Hospital, Montpellier
- Target Recruit Count
- 1000
- Registration Number
- NCT05681572
- Locations
- 🇫🇷
Uhmontpellier, Montpellier, France
Two-channel IV-PCA With Dexmedetomidine
- Conditions
- Interventions
- First Posted Date
- 2023-01-05
- Last Posted Date
- 2023-10-05
- Lead Sponsor
- Korea University Guro Hospital
- Target Recruit Count
- 110
- Registration Number
- NCT05672225
- Locations
- 🇰🇷
Korea University Guro Hospital, Seoul, Korea, Republic of
Dexmedetomidine Versus Magnesium Sulfate in Ultrasound Guided Bilateral Bi-level Erector Spinae Plane Block in Corrective Scoliosis Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-01-04
- Last Posted Date
- 2024-07-30
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 60
- Registration Number
- NCT05671081
- Locations
- 🇪🇬
Ain Shams University hospitals, Cairo, Egypt
Mechanism of Cardiac and Cerebral Function Injury Caused by Intraoperative Limb Ischemia-reperfusion
- Conditions
- Interventions
- First Posted Date
- 2022-12-22
- Last Posted Date
- 2022-12-22
- Lead Sponsor
- Hebei Medical University Third Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT05661227
- Locations
- 🇨🇳
The Third Hospital of Hebei Medical University, Shijiazhuang City, Hebei, China
Block Pressor Response to Intubation
- Conditions
- Interventions
- First Posted Date
- 2022-12-21
- Last Posted Date
- 2022-12-21
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 102
- Registration Number
- NCT05659212
Dexmedetomidine Versus Lidocaine in Attenuating Airway Reflexes During Recovery of Thyroidectomy Patients
- Conditions
- Interventions
- First Posted Date
- 2022-12-20
- Last Posted Date
- 2023-02-01
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 140
- Registration Number
- NCT05657028
- Locations
- 🇪🇬
Ainshams University Hospitals, Cairo, Egypt
Effect of Different Doses of Dexmedetomidine on Cerebral Oxygen Saturation and Postoperative Anxiety in Elderly Patients
- First Posted Date
- 2022-12-07
- Last Posted Date
- 2024-08-23
- Lead Sponsor
- The First Hospital of Qinhuangdao
- Target Recruit Count
- 105
- Registration Number
- NCT05640427
- Locations
- 🇨🇳
The First hosptial of Qinhuangdao, Qinhuangdao, Hebei, China
Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass Grafting
- Conditions
- Interventions
- First Posted Date
- 2022-12-07
- Last Posted Date
- 2023-04-18
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 70
- Registration Number
- NCT05640453
- Locations
- 🇪🇬
Islam Morsy, Tanta, El-Gharbia Governorate, Egypt
Pregabalin Versus Dexmedetomidine for Delirium Prevention After Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2022-12-07
- Last Posted Date
- 2024-12-04
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 60
- Registration Number
- NCT05640479
- Locations
- 🇪🇬
Tanta University, Tanta, ElGharbiaa, Egypt
Drug Development Updates
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