Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
Effect of Adding Different Concentrations of Dexmedetomidine to Bupivacaine in Caudal Block for Pediatrics
- Conditions
- Caudal Block for Postoperative Analgesia
- Interventions
- First Posted Date
- 2024-10-31
- Last Posted Date
- 2024-11-13
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 50
- Registration Number
- NCT06668220
Dexmedetomidine as an Intrathecal Adjuvant to Hyperbaric Bupivacaine for Postoperative Analgesia in Patients Undergoing Arthroscopic Anterior Cruciate Ligament Reconstruction Surgeries
- Conditions
- DexmedetomidineIntrathecalAdjuvantHyperbaric BupivacaineAnalgesiaArthroscopic Anterior Cruciate Ligament Reconstruction
- Interventions
- First Posted Date
- 2024-10-31
- Last Posted Date
- 2024-10-31
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 64
- Registration Number
- NCT06667024
- Locations
- 🇪🇬
Tanta University, Tanta, El-Gharbia, Egypt
Dexmedetomidine and Bupivacaine Intra-articular for Postoperative Analgesia After Knee Arthroscopic Surgery
- Conditions
- Post Operative Analgesia
- Interventions
- First Posted Date
- 2024-10-30
- Last Posted Date
- 2025-04-22
- Lead Sponsor
- Al-Azhar University
- Target Recruit Count
- 75
- Registration Number
- NCT06665438
- Locations
- 🇪🇬
Al-Azhar University, Assiut, Egypt
Dexmedetomidine on Brain Injury Patients
- Conditions
- Brain Injuries
- Interventions
- Other: Placebo
- First Posted Date
- 2024-10-28
- Last Posted Date
- 2024-10-29
- Lead Sponsor
- Damanhour University
- Target Recruit Count
- 60
- Registration Number
- NCT06661980
- Locations
- 🇪🇬
Damanhour Teaching Hospital, General Organization for Teaching Hospitals and Institutes., Damanhūr, Elbehairah, Egypt
Perioperative Pain Management for Lumbar Spine Surgery
- Conditions
- Pain, Postoperative
- Interventions
- First Posted Date
- 2024-10-28
- Last Posted Date
- 2024-10-28
- Lead Sponsor
- Benha University
- Target Recruit Count
- 75
- Registration Number
- NCT06662318
- Locations
- 🇪🇬
Benha University, Banhā, El Qalyoubia, Egypt
Effect of Intravenous or Intrathecal Dexmedetomidine on Bupivacaine Spinal Block in Lower Abdominal Surgery
- Conditions
- Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
- Interventions
- First Posted Date
- 2024-10-23
- Last Posted Date
- 2024-10-23
- Lead Sponsor
- Al-Azhar University
- Target Recruit Count
- 50
- Registration Number
- NCT06654531
- Locations
- 🇪🇬
Azhar University, Assiut, Assuit, Egypt
The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery
- Conditions
- Open Heart SugeryNeuronal Damage
- Interventions
- First Posted Date
- 2024-10-23
- Last Posted Date
- 2024-10-23
- Lead Sponsor
- Sohag University
- Target Recruit Count
- 32
- Registration Number
- NCT06655025
- Locations
- 🇪🇬
Sohag University, Sohag, Egypt
Nerve Block Vs Sedation Infusion for Awake Fiberoptic Intubation.
- Conditions
- Superior Laryngeal Nerve BlockSedationDexmedetomidineAwake Fiberoptic IntubationHemimandibulectomyAnticipated Difficult Airway
- Interventions
- Drug: Superior laryngeal nerve block
- First Posted Date
- 2024-10-22
- Last Posted Date
- 2024-10-23
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 80
- Registration Number
- NCT06651905
- Locations
- 🇪🇬
Cairo University, Cairo, Egypt
Intra-Articular Dexmedetomidine: A Treatment for Chronic Knee Pain
- Conditions
- Chronic Knee Pain
- Interventions
- First Posted Date
- 2024-10-14
- Last Posted Date
- 2024-10-14
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 70
- Registration Number
- NCT06641206
- Locations
- 🇪🇬
Tanta University, Tanta, El Gharbyia, Egypt
Sphenopalatine Block Vs Dexmedetomidine Infusion in Trans Nasal Endoscopic Pituitary Surgery
- Conditions
- Sphenopalatine Ganglion Nerve BlockTransnasal Endoscopic Pitutary Surgery
- Interventions
- Other: General Anesthesia (control group)Procedure: Sphenopalatine Ganglion Block
- First Posted Date
- 2024-10-14
- Last Posted Date
- 2024-10-14
- Lead Sponsor
- Zagazig University
- Target Recruit Count
- 69
- Registration Number
- NCT06639659
- Locations
- 🇪🇬
Zagazig Univesity Hospital, Zagazig, Egypt
Drug Development Updates
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