Amprenavir

Generic Name
Amprenavir
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C25H35N3O6S
CAS Number
161814-49-9
Unique Ingredient Identifier
5S0W860XNR
Background

Amprenavir is a protease inhibitor used to treat HIV infection.

Indication

用于高效抗逆转录病毒疗法(HAART)的组成药物。

Associated Conditions
-
Associated Therapies
-

HIV Infection And Metabolic Abnormalities Protocol 1 (HAMA001)

First Posted Date
2005-09-19
Last Posted Date
2012-04-12
Lead Sponsor
Kirby Institute
Target Recruit Count
80
Registration Number
NCT00192660
Locations
🇦🇺

St. Vincent's Hospital, Sydney, New South Wales, Australia

Dual Boosted - Protease Inhibitor (PI) Pharmacokinetics (PK) Trial (Tipranavir / Ritonavir) in Highly Treatment-experienced HIV-1 Infected Patients

Phase 2
Completed
Conditions
First Posted Date
2003-03-21
Last Posted Date
2023-12-01
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
328
Registration Number
NCT00056641
Locations
🇺🇸

UT Southwestern, Dallas, Texas, United States

🇨🇦

Toronto General Hospital, Toronto, Ontario, Canada

🇩🇪

Boehringer Ingelheim Investigational Site, Stuttgart, Germany

and more 78 locations

Once-Daily Drug Regimen for HIV-Infected Patients

First Posted Date
2002-12-10
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
25
Registration Number
NCT00001968
Locations
🇺🇸

National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, United States

Comparing Standard-Dose Versus Adjusted-Dose Lopinavir/Ritonavir Therapy in HIV-Infected Persons With Drug Resistance

Phase 2
Completed
Conditions
First Posted Date
2002-09-19
Last Posted Date
2011-03-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
118
Registration Number
NCT00046033
Locations
🇺🇸

Univ of Miami, Miami, Florida, United States

🇺🇸

Case Western Reserve Univ, Cleveland, Ohio, United States

🇺🇸

Univ of Texas, Galveston, Galveston, Texas, United States

and more 3 locations

Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy

First Posted Date
2002-08-01
Last Posted Date
2022-07-22
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
1578
Registration Number
NCT00042289
Locations
🇺🇸

Usc La Nichd Crs, Los Angeles, California, United States

🇿🇦

Wits RHI Shandukani Research Centre CRS, Johannesburg, Gauteng, South Africa

🇺🇸

Boston Medical Center Ped. HIV Program NICHD CRS, Boston, Massachusetts, United States

and more 59 locations

A Study of 141W94 in Combination With Other Anti-HIV Drugs

Phase 1
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Glaxo Wellcome
Target Recruit Count
48
Registration Number
NCT00002372
Locations
🇺🇸

ViRx Inc, San Francisco, California, United States

🇺🇸

Univ of North Carolina at Chapel Hill / Duke Univ Med Ctr, Durham, North Carolina, United States

🇺🇸

Univ of California / San Diego Treatment Ctr, San Diego, California, United States

A Study of the Effects of Amprenavir, a Protease Inhibitor, on Carbohydrate and Fat Metabolism in HIV-Infected Patients

Phase 3
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Glaxo Wellcome
Registration Number
NCT00002245
Locations
🇺🇸

LAC / USC Med Ctr / Infectious Diseases, Los Angeles, California, United States

Drug Interactions of Amprenavir and Efavirenz, in Combination With a Second Protease Inhibitor, in HIV-Negative Volunteers

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
90
Registration Number
NCT00005762
Locations
🇺🇸

Stanford CRS, Palo Alto, California, United States

🇺🇸

University of Colorado Hospital CRS, Aurora, Colorado, United States

🇺🇸

Indiana Univ. School of Medicine, Infectious Disease Research Clinic, Indianapolis, Indiana, United States

and more 5 locations

A Study of Amprenavir in Patients With Protease Inhibitor-Related Complications

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Glaxo Wellcome
Registration Number
NCT00002417
Locations
🇺🇸

Glaxo Wellcome Inc, Research Triangle Park, North Carolina, United States

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