Bisoprolol
- Generic Name
- Bisoprolol
- Brand Names
- Ziac
- Drug Type
- Small Molecule
- Chemical Formula
- C18H31NO4
- CAS Number
- 66722-44-9
- Unique Ingredient Identifier
- Y41JS2NL6U
- Background
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure. It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternati...
- Indication
Bisoprolol is indicated for the treatment of mild to moderate hypertension. It may be used off-label to treat heart failure, atrial fibrillation, and angina pectoris.
- Associated Conditions
- Atrial Fibrillation, Cardiovascular Events, Chronic Stable Angina Pectoris, Heart Failure, Hypertension, Mild Hypertension, Premature Ventricular Contraction (PVC), Supraventricular Arrhythmias, Moderate Hypertension, Perioperative arrhythmia
- Associated Therapies
- -
Rate Control Therapy Evaluation in Permanent Atrial Fibrillation (RATE-AF)
- First Posted Date
- 2015-03-18
- Last Posted Date
- 2021-06-18
- Lead Sponsor
- University of Birmingham
- Target Recruit Count
- 161
- Registration Number
- NCT02391337
- Locations
- 🇬🇧
Queen Elizabeth Hospital, Birmingham, West Midlands, United Kingdom
🇬🇧City Hospital, Birmingham, West Midlands, United Kingdom
Chronic Beta-blockade and Cardiopulmonary Exercise in COPD
- Conditions
- Interventions
- First Posted Date
- 2015-03-05
- Last Posted Date
- 2019-06-24
- Lead Sponsor
- University of Dundee
- Target Recruit Count
- 10
- Registration Number
- NCT02380053
- Locations
- 🇬🇧
Asthma and Allergy Research Group, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom
Optimum Treatment for Drug-Resistant Hypertension
- Conditions
- Interventions
- First Posted Date
- 2015-02-23
- Last Posted Date
- 2015-07-03
- Lead Sponsor
- University of Cambridge
- Target Recruit Count
- 348
- Registration Number
- NCT02369081
- Locations
- 🇬🇧
University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
🇬🇧University of Birmingham, Birmingham, United Kingdom
🇬🇧University of Cambridge - Addenbrookes Hospital, Cambridge, United Kingdom
Comparative Effects of Moxonidine on Bone Metabolism, Vascular and Cellular Aging in Hypertensive Postmenopausal Women
- Conditions
- Interventions
- First Posted Date
- 2015-02-04
- Last Posted Date
- 2021-09-01
- Lead Sponsor
- National Research Center for Preventive Medicine
- Target Recruit Count
- 114
- Registration Number
- NCT02355821
- Locations
- 🇷🇺
National Research Center for Preventive Medicine, Moscow, Russian Federation
In Vivo Specificity of KUC 7483 CL Co-administered With Bisoprolol, Propranolol, and Acipimox in Healthy Male Subjects
- Conditions
- Interventions
- First Posted Date
- 2014-10-06
- Last Posted Date
- 2014-10-06
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 12
- Registration Number
- NCT02256722
Cardiotoxicity Prevention in Breast Cancer Patients Treated With Anthracyclines and/or Trastuzumab
- Conditions
- Interventions
- First Posted Date
- 2014-09-11
- Last Posted Date
- 2022-02-01
- Lead Sponsor
- Azienda Ospedaliero-Universitaria Careggi
- Target Recruit Count
- 262
- Registration Number
- NCT02236806
- Locations
- 🇮🇹
Azienda Ospedaliero-Universitaria Careggi, Florence University, Florence, Italy
Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS)
- Conditions
- Interventions
- First Posted Date
- 2014-06-24
- Last Posted Date
- 2018-04-18
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 150
- Registration Number
- NCT02171988
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
The Cardiac Insufficiency BIsoprolol Study in Japanese Patients With Chronic Heart Failure (CIBIS-J)
- First Posted Date
- 2014-05-14
- Last Posted Date
- 2014-05-14
- Lead Sponsor
- Mebix Inc
- Target Recruit Count
- 220
- Registration Number
- NCT02137733
- Locations
- 🇯🇵
Chukyo Hospital, Nagoya, Aichi, Japan
🇯🇵Takezawa Clinic, Nagoya, Aichi, Japan
🇯🇵St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan
Effects of Beta-blockade on Cardiopulmonary Exercise Testing
- Conditions
- Interventions
- First Posted Date
- 2014-04-08
- Last Posted Date
- 2014-04-08
- Lead Sponsor
- Michelle Mossa
- Target Recruit Count
- 55
- Registration Number
- NCT02106286
- Locations
- 🇬🇧
Aintree University Hospitals, Liverpool, United Kingdom
Hemodynamic Changes of Patients Receiving Atenolol/Bisoprolol
- First Posted Date
- 2013-09-11
- Last Posted Date
- 2014-12-05
- Lead Sponsor
- Hospital Italiano de Buenos Aires
- Target Recruit Count
- 80
- Registration Number
- NCT01939509
- Locations
- 🇦🇷
Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
Drug Development Updates
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