Montelukast
- Generic Name
- Montelukast
- Brand Names
- Singulair
- Drug Type
- Small Molecule
- Chemical Formula
- C35H36ClNO3S
- CAS Number
- 158966-92-8
- Unique Ingredient Identifier
- MHM278SD3E
- Background
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs. Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or complementary with the use of inhaled corticos...
- Indication
Montelukast is indicated for:
...
- Associated Conditions
- Asthma, Exercise-Induced Bronchospasm, Perennial Allergic Rhinitis (PAR), Seasonal Allergic Rhinitis
- Associated Therapies
- -
Bioequivalence Study of Montelukast, 5 mg Chewable Tablets (Pharmtechnology LLC, Belarus), and Singulair®, 5 mg Chewable Tablets (Merck Sharp & Dohme B.V., the Netherlands), in Healthy Volunteers Under Fasting Conditions
- First Posted Date
- 2019-04-01
- Last Posted Date
- 2019-06-06
- Lead Sponsor
- Pharmtechnology LLC
- Target Recruit Count
- 34
- Registration Number
- NCT03898193
- Locations
- 🇷🇺
State Autonomous Healthcare Facility of the Yaroslavl Region "Clinical Hospital No. 2", Yaroslavl, Yaroslavl Region, Russian Federation
Effect of Some Drugs on Rheumatoid Arithritis Activity
- First Posted Date
- 2018-12-10
- Last Posted Date
- 2018-12-10
- Lead Sponsor
- Sherief Abd-Elsalam
- Target Recruit Count
- 75
- Registration Number
- NCT03770923
- Locations
- 🇪🇬
Sherief Abd-Elsalam, Tanta, Egypt
Montelukast and Loratadine in Children With Asthma
- Conditions
- Interventions
- First Posted Date
- 2017-12-13
- Last Posted Date
- 2017-12-13
- Lead Sponsor
- Innovacion y Desarrollo de Estrategias en Salud
- Target Recruit Count
- 80
- Registration Number
- NCT03372473
Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin
- First Posted Date
- 2017-04-27
- Last Posted Date
- 2017-12-15
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 26
- Registration Number
- NCT03131973
- Locations
- 🇺🇸
PPD Development, LP, Austin, Texas, United States
TEAM (Trial on Efficacy and Quality of Life Among Asthmatic Patient With Montelukast)
- First Posted Date
- 2017-03-30
- Last Posted Date
- 2018-07-09
- Lead Sponsor
- PharmEvo Pvt Ltd
- Target Recruit Count
- 180
- Registration Number
- NCT03096327
- Locations
- 🇵🇰
Dr. Nadeem Rizvi, Karachi, Sindh, Pakistan
Effects of a Orally Inhaled Fluticasone Furoate on Growth Velocity in Prepubertal, Paediatric Subjects With Asthma Over a Year
- Conditions
- Interventions
- First Posted Date
- 2016-09-07
- Last Posted Date
- 2024-01-17
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 477
- Registration Number
- NCT02889809
- Locations
- 🇿🇦
GSK Investigational Site, Cape Town, South Africa
Does Montelukast Decrease Post Adenotonsillectomy Pain in Children
- First Posted Date
- 2016-06-08
- Last Posted Date
- 2024-11-22
- Lead Sponsor
- Children's Hospital Medical Center, Cincinnati
- Target Recruit Count
- 117
- Registration Number
- NCT02793375
- Locations
- 🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
Fractional Concentration of Exhaled NO(FeNO) to Direct The Treatment of Sub-acute Cough
- First Posted Date
- 2016-01-14
- Last Posted Date
- 2022-07-22
- Lead Sponsor
- Beijing Chao Yang Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT02655562
- Locations
- 🇨🇳
Mingming Jiang, Beijing, China
Montelukast for Treatment of Uremic Pruritus
- Conditions
- Interventions
- First Posted Date
- 2015-09-24
- Last Posted Date
- 2015-09-24
- Lead Sponsor
- Shiraz University of Medical Sciences
- Target Recruit Count
- 73
- Registration Number
- NCT02559388
Montelukast and Fexofenadine Versus Montelukast and Levocetrizine Combination in Allergic Rhinitis
- Conditions
- Interventions
- First Posted Date
- 2015-09-16
- Last Posted Date
- 2015-09-16
- Lead Sponsor
- Indira Gandhi Medical College, Shimla
- Target Recruit Count
- 70
- Registration Number
- NCT02551536
Drug Development Updates
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