Montelukast
- Generic Name
- Montelukast
- Brand Names
- Singulair
- Drug Type
- Small Molecule
- Chemical Formula
- C35H36ClNO3S
- CAS Number
- 158966-92-8
- Unique Ingredient Identifier
- MHM278SD3E
- Background
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs. Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or complementary with the use of inhaled corticos...
- Indication
Montelukast is indicated for:
...
- Associated Conditions
- Asthma, Exercise-Induced Bronchospasm, Perennial Allergic Rhinitis (PAR), Seasonal Allergic Rhinitis
- Associated Therapies
- -
A Phase 1 Drug-drug Interaction Study in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2014-08-27
- Last Posted Date
- 2014-11-18
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 20
- Registration Number
- NCT02227173
- Locations
- 🇺🇸
Healthcare Discoveries, LLC d/b/a ICON Development Solutions, San Antonio, Texas, United States
Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery
- Conditions
- Interventions
- First Posted Date
- 2014-04-10
- Last Posted Date
- 2020-11-23
- Target Recruit Count
- 50
- Registration Number
- NCT02110654
- Locations
- 🇨🇳
the first affiliated hospital, Sun Yat-sen University, Guangzhou, Guangdong, China
Pilot Study Testing a New Strategy for Management of Spontaneous Preterm Birth
- Conditions
- Interventions
- First Posted Date
- 2014-04-09
- Last Posted Date
- 2015-03-04
- Lead Sponsor
- Université de Sherbrooke
- Target Recruit Count
- 100
- Registration Number
- NCT02108886
- Locations
- 🇨🇦
Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada
Safety and the Pharmacokinetic Study of Characteristics of MKT-N2 (Montelukast) and Singulair® (Montelukast Sodium)to Treat Asthma
- Conditions
- Interventions
- First Posted Date
- 2014-01-07
- Last Posted Date
- 2015-04-29
- Lead Sponsor
- PharmaKing
- Target Recruit Count
- 40
- Registration Number
- NCT02029313
- Locations
- 🇰🇷
Inha University Hospital, Incheon, Junggu, Korea, Republic of
Role of Leukotriene Receptor Antagonists in Treatment of Chronic Periodontitis
- First Posted Date
- 2013-12-18
- Last Posted Date
- 2013-12-19
- Lead Sponsor
- Tatyasaheb Kore Dental College
- Target Recruit Count
- 60
- Registration Number
- NCT02014532
- Locations
- 🇮🇳
Tatyasaheb Kore Dental College and Research Centre, New Pargaon, Kolhapur, Maharashtra, India
A Study of JNJ-54767414 (HuMax CD38) (Anti-CD38 Monoclonal Antibody) in Combination With Backbone Treatments for the Treatment of Patients With Multiple Myeloma
- First Posted Date
- 2013-12-03
- Last Posted Date
- 2024-12-06
- Lead Sponsor
- Janssen Research & Development, LLC
- Target Recruit Count
- 240
- Registration Number
- NCT01998971
Montelukast for Children With Chronic Otitis Media With Effusion (COME): A Double-blind, Placebo-controlled Study
- Conditions
- Interventions
- First Posted Date
- 2013-10-23
- Last Posted Date
- 2013-10-23
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Target Recruit Count
- 52
- Registration Number
- NCT01967498
Effects of Montelukast on Airway Regulatory T Cells in Asthma
- First Posted Date
- 2013-09-27
- Last Posted Date
- 2013-09-27
- Lead Sponsor
- Kurume University
- Target Recruit Count
- 15
- Registration Number
- NCT01951898
- Locations
- 🇯🇵
Kurume University School of Medicine, Kurume, Japan
Study of the Efficacy and Safety of MK-0476 in Japanese Pediatric Participants With Seasonal Allergic Rhinitis (MK-0476-519)
- First Posted Date
- 2013-05-20
- Last Posted Date
- 2024-06-17
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 220
- Registration Number
- NCT01857063
A Mechanistic Study to Evaluate the Efficacy of Montelukast on Airway Function in Asthma
- Conditions
- Interventions
- First Posted Date
- 2013-04-26
- Last Posted Date
- 2013-04-26
- Lead Sponsor
- Karolinska University Hospital
- Target Recruit Count
- 14
- Registration Number
- NCT01841164
- Locations
- 🇸🇪
Karolinska University Hospital, Stockholm, Sweden
Drug Development Updates
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