Adapalene
- Generic Name
- Adapalene
- Brand Names
- Cabtreo, Differin, Epiduo, Panoxyl, Tactupump
- Drug Type
- Small Molecule
- Chemical Formula
- C28H28O3
- CAS Number
- 106685-40-9
- Unique Ingredient Identifier
- 1L4806J2QF
- Background
Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of a...
- Indication
Adapalene is indicated for the topical treatment of acne vulgaris in patients aged 12 and over. It is also indicated for acne vulgaris in combination with benzoyl peroxide and in a triple combination therapy with benzoyl peroxide and clindamycin.
- Associated Conditions
- Acne Vulgaris
- Associated Therapies
- -
A Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris
- Conditions
- Interventions
- First Posted Date
- 2007-01-15
- Last Posted Date
- 2021-02-18
- Lead Sponsor
- Galderma R&D
- Target Recruit Count
- 1670
- Registration Number
- NCT00421993
- Locations
- 🇺🇸
UTSW Medical Center at Dallas, Dallas, Texas, United States
🇺🇸Dawes Fretzin Clinical Research Group, LLC, Indianapolis, Indiana, United States
🇺🇸Dolby Research, LLC, Baton Rouge, Louisiana, United States
Drug Development Updates
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