Botulinum toxin type A

Generic Name
Botulinum toxin type A
Brand Names
Botox, Botox Cosmetic, Dysport, Jeuveau, Xeomin, Nuceiva
Drug Type
Biotech
Chemical Formula
-
CAS Number
93384-43-1
Unique Ingredient Identifier
0A6JH35GMQ
Background

In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use. With a wide variety of applications and favourable safety profile, Botulinum toxin A injection is a minimally invasive and promising treatment for cosmetic imperfections, muscle spasms, and other condit...

Indication

Botulinum toxin A is indicated for a variety of conditions, depending on the preparations. Cosmetically, it is used for the treatment of facial fine lines and wrinkles, specifically for upper facial rhytides, including forehead, lateral canthus, and glabellar lines.
...

Associated Conditions
Bladder pain, Blepharospasm, Cervical Dystonia, Chronic Migraine, Diabetic Neuropathies, Epicondylitis, Equinus deformity of foot, acquired, Facial Skin Wrinkles, Glabellar Frown Lines (GL), Lower Limb Spasticity, Myofascial Pain Syndrome, Neurogenic Detrusor Overactivity, Neurogenic Thoracic Outlet Syndrome, Overactive Bladder Syndrome (OABS), Post Stroke Pain, Postherpetic Neuralgia, Sialorrhea, Spasticity, Spinal Cord Injuries, Strabismus, TMJ Disorders, Trigeminal Neuralgia (TN), Upper Limb Spasticity, Urinary Incontinence (UI), Hypertonicity disorders of the 7th nerve, Moderate Glabellar Frown Lines (GL), Severe Glabellar Frown Lines (GL), Severe axillary hyperhidrosis
Associated Therapies
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Not Just for Wrinkles Anymore: Botox Takes on Range of Medical Conditions

Botox, originally used for crossed eyes, now treats migraines, excessive sweating, and more. It blocks nerve signals to muscles, offering relief but requiring frequent injections. Multiple brands exist, each with potential for unique responses. Training and expertise are crucial to avoid side effects.
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Vensica Medical Secures $11M in Funding to Support Phase 2 Trials for Overactive Bladder

Vensica Medical secures $11M to fund Phase 2 trials for OAB treatment using Xeomin® via a needle-free device.
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New Phase III READY-4 Data Demonstrate Long-Term Safety and Efficacy of ...

Galderma announces phase III READY-4 trial data showing long-term safety of RelabotulinumtoxinA for frown lines and crow’s feet, with efficacy and patient satisfaction maintained across multiple treatments. The study met primary and secondary endpoints, with mild or moderate treatment-emergent adverse events reported by 18% of participants. RelabotulinumtoxinA, developed using PEARL™ Technology, is the first ready-to-use liquid neuromodulator optimized for simple volumetric dosing.
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BOTOX® Cosmetic (onabotulinumtoxinA) Receives FDA Approval for Moderate to Severe

BOTOX® Cosmetic receives FDA approval for temporary improvement in appearance of moderate to severe vertical bands connecting jaw and neck (platysma bands) in adults, expanding its aesthetic indications to include forehead lines, frown lines, crow’s feet lines, and now platysma bands.
finance.yahoo.com
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BOTOX® Cosmetic (onabotulinumtoxinA) Receives FDA Approval for Moderate to Severe ...

BOTOX® Cosmetic receives FDA approval for temporary improvement in appearance of moderate to severe vertical bands connecting the jaw and neck (platysma bands) in adults, expanding its aesthetic indications to include forehead lines, frown lines, crow's feet lines, and now platysma bands.
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