Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. Seniors absorb calcium lactate, gluconate and citrate better unless they take their calcium supplement with a full breakfast.
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. It is vital in cell signaling, muscular contractions, bone health, and signalling cascades.
School of Dentistry, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan
Stanford Children's Health, Lucile Packard Children's Hospital, Stanford, California, United States
Harbin Medical University, Harbin, Heilongjiang, China
Weill Cornell Medicine, New York, New York, United States
Mansoura university, Mansoura, Egypt
Cancer Institute Hospital of JFCR, Koto-Ku, Tokyo, Japan
Osaka Medical and Pharmaceutical University Hospital, Takatsuki-shi, Osaka, Japan
National Cancer Center Hospital East, Kashiwa-shi, Chiba, Japan
Soroka Medical Center, Beer Sheva, Israel
Hadassah Ein Kerem Medical Center, Jerusalem, Israel
Barzilai Medical Center, Ashkelon, Israel
Shanghai General Hospital, Shanghai, Shanghai, China
Liu Tianshu, Shanghai, Shanghai, China
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