MedPath

Calcium

Generic Name
Calcium
Drug Type
Small Molecule
Chemical Formula
Ca
CAS Number
7440-70-2
Unique Ingredient Identifier
SY7Q814VUP
Background

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. Seniors absorb calcium lactate, gluconate and citrate better unless they take their calcium supplement with a full breakfast.

Indication

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. It is vital in cell signaling, muscular contractions, bone health, and signalling cascades.

Associated Conditions
Calcium Deficiency, Deficiency, Vitamin D, Osteodystrophy, Osteomalacia, Osteoporosis, Chronic Hypocalcemia, Chronic Hypocalcemia caused by anticonvulsant medications
Associated Therapies
Care of the Joint, Mineral supplementation therapy, Nutritional supplementation

Calcium Folinate Treatment of Spastic Paraplegia 56

Early Phase 1
Recruiting
Conditions
Hereditary Spastic Paraplegia
Interventions
First Posted Date
2024-06-27
Last Posted Date
2024-06-27
Lead Sponsor
Shanghai 6th People's Hospital
Target Recruit Count
10
Registration Number
NCT06478238
Locations
🇨🇳

Shanghai 6th People's Hospita, Shanghai, Shanghai, China

Adebrelimab in Combination With NALIRIFOX in Locally Advanced Pancreatic Cancer

First Posted Date
2024-06-26
Last Posted Date
2024-08-09
Lead Sponsor
Fudan University
Target Recruit Count
87
Registration Number
NCT06475326
Locations
🇨🇳

Fudan University Shanghai Cancer Center, Shanghai, China

Investigate"Clinically" the Effectiveness of Boswellia Based Intracanal Medication Compared to Calcium Hydroxide Ca(OH)2 and Ledermix on the Levels of Bacteria and Inflammatory Cytokines in Root Canals and Periradicular Tissues of Teeth With Apical Periodontitis

Phase 2
Recruiting
Conditions
Microbial Colonization
Interventions
Drug: Boswellia
Drug: Leddermix
First Posted Date
2024-06-20
Last Posted Date
2024-06-20
Lead Sponsor
Mansoura University
Target Recruit Count
36
Registration Number
NCT06466538
Locations
🇪🇬

May Abuzoor, Mansoura, Egypt

Effectiveness of Glycyrrhizin as Intracanal Medication in Root Canal Disinfection and Inflammatory Cytokines

Phase 2
Recruiting
Conditions
Intracanal Medication
Interventions
Drug: Leddermix
Drug: Glycirrhizin
First Posted Date
2024-06-11
Last Posted Date
2024-07-03
Lead Sponsor
Mansoura University
Target Recruit Count
36
Registration Number
NCT06453304
Locations
🇪🇬

Alaa Reda Mohamed Eltantawi, Mansoura, Egypt

Short-course Radiotherapy or Long-course Chemoradiation Followed by MFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer

Phase 2
Recruiting
Conditions
Rectal Neoplasms
Interventions
Radiation: Short-course radiotherapy
Radiation: Long-course chemoradiation
First Posted Date
2024-05-16
Last Posted Date
2025-03-19
Lead Sponsor
Pei-Rong Ding
Target Recruit Count
66
Registration Number
NCT06417476
Locations
🇨🇳

651 Dongfeng Road East, Guangzhou, Guangdong, China

A Study on the Prevention and Treatment of GIOP With Eldecalcitol

Phase 4
Not yet recruiting
Conditions
Osteoporosis
Rheumatoid Arthritis
Osteopenia
Interventions
First Posted Date
2024-04-25
Last Posted Date
2024-04-25
Lead Sponsor
Chinese SLE Treatment And Research Group
Target Recruit Count
314
Registration Number
NCT06385093
Locations
🇨🇳

Beijing Luhe hospital, Capital Medical University, Beijing, Beijing, China

🇨🇳

Peking Union Medical College Hospital, Beijing, Beijing, China

🇨🇳

Beijing Shunyi hospital, Beijing, Beijing, China

and more 4 locations

Comparing the Safety and Efficacy of First-line Polychemotherapy and Polychemotherapy in Combination With PIPAC Sessions

Phase 2
Recruiting
Conditions
Gastric Cancer
Interventions
Procedure: Diagnostic laparoscopy
Combination Product: dPIPAC ( The description of the standard diagnostic laparoscopy procedure and the session of PIPAC (dPIPAC)).
First Posted Date
2024-03-15
Last Posted Date
2024-03-15
Lead Sponsor
Nizhny Novgorod Regional Clinical Oncology Center
Target Recruit Count
106
Registration Number
NCT06313801
Locations
🇷🇺

Research Institute of Clinical Oncology "Nizhny Novgorod Regional Clinical Oncological Dispensary", Nizhny Novgorod, Russian Federation

Effect of Calcium Silicate Based Root Canal Medicament on Inflammatory Mediators

Not Applicable
Completed
Conditions
Periapical; Infection
Interventions
First Posted Date
2024-03-13
Last Posted Date
2024-03-13
Lead Sponsor
Ataturk University
Target Recruit Count
60
Registration Number
NCT06307678
Locations
🇹🇷

Ataturk University, Erzurum, Turkey

A Study of Initiation Timing of VTE Prevention After Colorectal Cancer Surgery

Recruiting
Conditions
Colorectal Cancer
Interventions
First Posted Date
2024-02-14
Last Posted Date
2024-08-09
Lead Sponsor
RenJi Hospital
Target Recruit Count
914
Registration Number
NCT06259149
Locations
🇨🇳

Department of Gastrointestinal Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China

Administration Of Calcium Gluconate for The Reduction of Blood Loss During Elective Cesarean Delivery

Not Applicable
Recruiting
Conditions
Elective Cesarean Delivery
Interventions
First Posted Date
2024-02-01
Last Posted Date
2025-01-28
Lead Sponsor
Rambam Health Care Campus
Target Recruit Count
1180
Registration Number
NCT06235749
Locations
🇮🇱

Shamir Medical Center, Be'er Ya'aqov, Israel

🇮🇱

Rambam Medical Center, Haifa, Israel

🇮🇱

Edith Wolfson Medical Center, H̱olon, Israel

and more 1 locations
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