MedPath

Calcium

Generic Name
Calcium
Drug Type
Small Molecule
Chemical Formula
Ca
CAS Number
7440-70-2
Unique Ingredient Identifier
SY7Q814VUP
Background

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. Seniors absorb calcium lactate, gluconate and citrate better unless they take their calcium supplement with a full breakfast.

Indication

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. It is vital in cell signaling, muscular contractions, bone health, and signalling cascades.

Associated Conditions
Calcium Deficiency, Deficiency, Vitamin D, Osteodystrophy, Osteomalacia, Osteoporosis, Chronic Hypocalcemia, Chronic Hypocalcemia caused by anticonvulsant medications
Associated Therapies
Care of the Joint, Mineral supplementation therapy, Nutritional supplementation

Clinical And Radiographic Evaluation Of Premixed Bio-ceramic MTA In Indirect Pulp Capping Of Young Permanent Molars

Phase 3
Not yet recruiting
Conditions
Indirect Pulp Capping
Interventions
First Posted Date
2023-07-03
Last Posted Date
2023-08-01
Lead Sponsor
Cairo University
Target Recruit Count
40
Registration Number
NCT05928858

Comparison of Calcium Silicate-based Sealer and Epoxy Resin-based Sealer

Phase 3
Completed
Conditions
Pain, Postoperative
Pulpitis - Irreversible
Interventions
Drug: Epoxy resin-based sealers (ERS)
First Posted Date
2023-06-15
Last Posted Date
2023-06-15
Lead Sponsor
University of Medicine and Pharmacy at Ho Chi Minh City
Target Recruit Count
42
Registration Number
NCT05904184
Locations
🇻🇳

University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam

Effects of Calcium Hydroxylapatite on Cellulite Dimples in the Buttocks

Phase 1
Completed
Conditions
Cellulite
Interventions
First Posted Date
2023-06-01
Last Posted Date
2023-07-17
Lead Sponsor
Kalpna Kay Durairaj, MD, FACS
Target Recruit Count
25
Registration Number
NCT05885035
Locations
🇺🇸

K. Kay Durairaj, MD, FACS, A Medical Corporation, Pasadena, California, United States

Comparison of Efficacy of Denosumab With Eldecalcitol or Native Vitamin D in Postmenopausal Women With Osteoporosis.

Phase 4
Recruiting
Conditions
Osteoporosis in Postmenopausal Women
Interventions
First Posted Date
2023-06-01
Last Posted Date
2024-02-21
Lead Sponsor
Xi'an Honghui Hospital
Target Recruit Count
100
Registration Number
NCT05884372
Locations
🇨🇳

Zeng,Yuhong, Xi'an, China

A Phase Ib/II Clinical Study on AK112 Combined or Not Combined With AK119 in pMMR/MSS Colorectal Cancer

First Posted Date
2023-05-06
Last Posted Date
2025-03-03
Lead Sponsor
Akeso
Target Recruit Count
170
Registration Number
NCT05846867
Locations
🇨🇳

Cancer Hospital Affiliated to Harbin Medical University, Harbin, China

Bioequivalence Study of Calcium Hydroxybenzene Sulphonate Dispersible Tablets in Chinese Healthy Volunteers

First Posted Date
2023-04-03
Last Posted Date
2023-04-03
Lead Sponsor
Beijing Tongren Hospital
Target Recruit Count
56
Registration Number
NCT05794919
Locations
🇨🇳

National Institue for Drug Clinical Trials, Beijing, Beijing, China

LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic Conditions

Phase 4
Recruiting
Conditions
Stable Ischemic Heart Disease
Angina
Interventions
First Posted Date
2023-03-27
Last Posted Date
2025-02-06
Lead Sponsor
Yale University
Target Recruit Count
960
Registration Number
NCT05786417
Locations
🇺🇸

Yale School of Medicine, New Haven, Connecticut, United States

🇺🇸

Wellstar Research Institute, Marietta, Georgia, United States

🇺🇸

Cook County Health, Chicago, Illinois, United States

and more 6 locations

Pre-diltiazem, Calcium Versus Placebo for Atrial Fibrillation With Rapid Ventricular Response

Phase 2
Not yet recruiting
Conditions
Atrial Fibrillation With Rapid Ventricular Response
Hypotension
Interventions
Drug: Placebo
First Posted Date
2023-01-20
Last Posted Date
2023-01-20
Lead Sponsor
Ascension Health
Target Recruit Count
378
Registration Number
NCT05691959

Effect of Bromelain Versus Calcium Hydroxide as an Intracanal Medication on the Intensity of Postoperative Pain and Bacterial Load Reduction in Necrotic Single Rooted Lower Premolars

Early Phase 1
Not yet recruiting
Conditions
Intracanal Medication
Bacterial Load Reduction
Bromelain
Calcium Hydroxide
Interventions
Biological: bromelain
First Posted Date
2023-01-18
Last Posted Date
2023-01-18
Lead Sponsor
Cairo University
Target Recruit Count
30
Registration Number
NCT05687760

Effect of N-acetylcysteine Versus Calcium Hydroxide Used as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Levels of MMP -9 in Periapical Fluids in Patients With Necrotic Pulp

Early Phase 1
Not yet recruiting
Conditions
Calcium Hydroxide
N-acetylcystine
Mediators
Intracanal Medication
Interventions
First Posted Date
2022-12-27
Last Posted Date
2022-12-27
Lead Sponsor
Cairo University
Target Recruit Count
30
Registration Number
NCT05666089
Locations
🇪🇬

FACULTY OF DENTISTRY-cairo university, Cairo, Egypt

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