Pentamidine
- Generic Name
- Pentamidine
- Brand Names
- Nebupent, Pentam
- Drug Type
- Small Molecule
- Chemical Formula
- C19H24N4O2
- CAS Number
- 100-33-4
- Unique Ingredient Identifier
- 673LC5J4LQ
- Background
Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
- Indication
For the treatment of pneumonia due to Pneumocystis carinii.
- Associated Conditions
- Pneumocystis Jirovecii Pneumonia, Trypanosomiasis
- Associated Therapies
- -
The Safety and Effectiveness of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Who Have Had PCP Before
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Fisons
- Registration Number
- NCT00002291
- Locations
- πΊπΈ
Fisons Corp, Rochester, New York, United States
A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-04
- Target Recruit Count
- 600
- Registration Number
- NCT00000991
- Locations
- πΊπΈ
Chicago Children's CRS, Chicago, Illinois, United States
πΊπΈJohns Hopkins Adult AIDS CRS, Baltimore, Maryland, United States
πΊπΈCase CRS, Cleveland, Ohio, United States
A Study of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-04
- Target Recruit Count
- 20
- Registration Number
- NCT00001003
- Locations
- πΊπΈ
SUNY - Stony Brook, Stony Brook, New York, United States
Aerosols in the Treatment of Asymptomatic Pneumocystis Pneumonia: A Pilot Study Assessing the Effectiveness of Aerosolized Pentamidine as Treatment of Subclinical Pneumocystis Infection in Patients With No Clinical Symptoms
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-02
- Target Recruit Count
- 20
- Registration Number
- NCT00000707
- Locations
- πΊπΈ
SUNY - Stony Brook, Stony Brook, New York, United States
Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-04
- Target Recruit Count
- 364
- Registration Number
- NCT00001013
- Locations
- πΊπΈ
Tulane Univ School of Medicine, New Orleans, Louisiana, United States
πΊπΈCharity Hosp / Tulane Univ Med School, New Orleans, Louisiana, United States
πΊπΈSUNY / State Univ of New York, Syracuse, New York, United States
Islet Transplantation for Type 1 Diabetes
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2017-03-15
- Target Recruit Count
- 36
- Registration Number
- NCT00014911
- Locations
- π©πͺ
Justus-Leibig University, Giessen, Germany
π¨π¦University of Alberta, Edmonton, Alberta, Canada
π¨πUniversity of Geneva, Geneva, Switzerland
A Study of Two Forms of Pentamidine in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- LyphoMed
- Registration Number
- NCT00002292
- Locations
- πΊπΈ
LyphoMed Inc, Rosemont, Illinois, United States
An Open Label Study to Evaluate the Long-Term Safety and Effectiveness of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Fisons
- Registration Number
- NCT00002030
- Locations
- πΊπΈ
Fisons Corp, Rochester, New York, United States
A Study of Pentamidine Plus Dapsone in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients Who Cannot Take Trimethoprim or Sulfonamides
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 400
- Registration Number
- NCT00001028
- Locations
- πΊπΈ
Community Consortium of San Francisco, San Francisco, California, United States
πΊπΈDenver CPCRA / Denver Public Hlth, Denver, Colorado, United States
πΊπΈWilmington Hosp / Med Ctr of Delaware, Wilmington, Delaware, United States
Comparison of Three Treatments for Pneumocystis Pneumonia in AIDS Patients
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-03
- Target Recruit Count
- 240
- Registration Number
- NCT00000730
- Locations
- πΊπΈ
Julio Arroyo, West Columbia, South Carolina, United States
Drug Development Updates
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