Ganciclovir
- Generic Name
- Ganciclovir
- Brand Names
- Cytovene, Zirgan
- Drug Type
- Small Molecule
- Chemical Formula
- C9H13N5O4
- CAS Number
- 82410-32-0
- Unique Ingredient Identifier
- P9G3CKZ4P5
- Background
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
- Indication
For induction and maintenance in the treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). Also used in the treatment of severe cytomegalovirus (CMV) disease, including CMV pneumonia, CMV gastrointestinal disease, and disseminated CMV infections, in immunocompromised pat...
- Associated Conditions
- CMV colitis, Cytomegalovirus (CMV) Infections, Cytomegalovirus Retinitis, Cytomegalovirus gastroesophagitis, Varicella-zoster Progressive outer retinal necrosis, Acute Herpetic keratitis, Cytomegalovirus neurological disease, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- -
Evaluation of the Prophylactic Use of Letermovir in Kidney Transplant Recipients at Risk of Cytomegalovirus Infection
- Conditions
- Interventions
- First Posted Date
- 2024-04-02
- Last Posted Date
- 2024-04-02
- Lead Sponsor
- Hospital do Rim e Hipertensão
- Target Recruit Count
- 100
- Registration Number
- NCT06341686
Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid
- First Posted Date
- 2022-10-13
- Last Posted Date
- 2024-07-01
- Lead Sponsor
- Gene Surgery LLC
- Target Recruit Count
- 21
- Registration Number
- NCT05578820
- Locations
- 🇷🇺
FSBI National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of the Ministry of Health of Russia, Moscow, Russian Federation
🇷🇺FSBI N.N. Blokhin National Medical Research Center of Oncology of the Ministry of Health of Russia, Moscow, Russian Federation
🇷🇺National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, Moscow, Russian Federation
Cytomegalovirus (CMV) Viremia and Disease Occurrence in Pediatric Allogeneic Stem Cell Transplantation Recipients
- First Posted Date
- 2020-07-20
- Last Posted Date
- 2023-10-26
- Lead Sponsor
- New York Medical College
- Target Recruit Count
- 100
- Registration Number
- NCT04478474
- Locations
- 🇺🇸
New York Medical College, Valhalla, New York, United States
Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC)
- First Posted Date
- 2019-10-18
- Last Posted Date
- 2021-07-21
- Target Recruit Count
- 104
- Registration Number
- NCT04132115
- Locations
- 🇮🇹
Anesthesiology and Intensive Care Clinic - Department of Medicine - ASUIUD, Udine, Italy
🇮🇹Terapia Intensiva 1, Udine, Italy
(Val)Ganciclovir TDM in Transplant Recipients
- Conditions
- Interventions
- First Posted Date
- 2018-10-09
- Last Posted Date
- 2019-10-10
- Lead Sponsor
- University Medical Center Groningen
- Target Recruit Count
- 100
- Registration Number
- NCT03698435
- Locations
- 🇳🇱
UMCG, Groningen, Netherlands
Clinical Trial of Efficacy and Safety of the Combination of Reduced Duration Prophylaxis Followed by Immuno-guided Prophylaxis in Lung Transplant Recipients.
- Conditions
- Interventions
- First Posted Date
- 2018-10-09
- Last Posted Date
- 2023-09-15
- Target Recruit Count
- 150
- Registration Number
- NCT03699254
- Locations
- 🇪🇸
Hospital Universitario 12 de Octubre, Madrid, Spain
🇪🇸Hospital Univesitario Reina Sofía, Córdoba, Spain
🇪🇸Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain
High-dose Intravitreal Injection of Ganciclovir for the Treatment of CMVR in HIV-negative Patients
- First Posted Date
- 2018-07-26
- Last Posted Date
- 2018-07-26
- Target Recruit Count
- 33
- Registration Number
- NCT03598452
CMV-CTL for the Treatment of CMV Infection After HSCT
- Conditions
- Interventions
- First Posted Date
- 2016-12-28
- Last Posted Date
- 2023-04-25
- Target Recruit Count
- 5
- Registration Number
- NCT03004261
- Locations
- 🇨🇳
Shanghai Jiao Tong University Affilated Shanghai General Hospital, Shanghai, Shanghai, China
The Strategy in the Prevention of Renal Post-transplant Cytomegalovirus Infection Among Chinese Population
- Conditions
- Interventions
- First Posted Date
- 2016-11-25
- Last Posted Date
- 2016-12-02
- Target Recruit Count
- 450
- Registration Number
- NCT02973464
- Locations
- 🇨🇳
the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China
Efficacy and Safety Study of Maribavir Treatment Compared to Investigator-assigned Treatment in Transplant Recipients With Cytomegalovirus (CMV) Infections That Are Refractory or Resistant to Treatment With Ganciclovir, Valganciclovir, Foscarnet, or Cidofovir
- Conditions
- Interventions
- First Posted Date
- 2016-10-13
- Last Posted Date
- 2021-11-03
- Lead Sponsor
- Shire
- Target Recruit Count
- 352
- Registration Number
- NCT02931539
- Locations
- 🇺🇸
University of Maryland, Baltimore, Maryland, United States
🇺🇸Johns Hopkins Hospital, Baltimore, Maryland, United States
🇺🇸University of Southern California, Los Angeles, California, United States
Drug Development Updates
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