Ganciclovir
- Generic Name
- Ganciclovir
- Brand Names
- Cytovene, Zirgan
- Drug Type
- Small Molecule
- Chemical Formula
- C9H13N5O4
- CAS Number
- 82410-32-0
- Unique Ingredient Identifier
- P9G3CKZ4P5
- Background
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
- Indication
For induction and maintenance in the treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). Also used in the treatment of severe cytomegalovirus (CMV) disease, including CMV pneumonia, CMV gastrointestinal disease, and disseminated CMV infections, in immunocompromised pat...
- Associated Conditions
- CMV colitis, Cytomegalovirus (CMV) Infections, Cytomegalovirus Retinitis, Cytomegalovirus gastroesophagitis, Varicella-zoster Progressive outer retinal necrosis, Acute Herpetic keratitis, Cytomegalovirus neurological disease, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- -
Gene Therapy in Treating Patients With Primary Brain Tumors
- Conditions
- First Posted Date
- 2004-07-29
- Last Posted Date
- 2019-03-13
- Lead Sponsor
- Abramson Cancer Center at Penn Medicine
- Registration Number
- NCT00002824
- Locations
- 🇺🇸
University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, United States
Vaccine Therapy and Ganciclovir in Treating Patients With Mesothelioma
- Conditions
- Locations
- 🇺🇸
Louisiana State University School of Medicine, New Orleans, Louisiana, United States
Biological Therapy and Gene Therapy in Treating Children With Recurrent or Refractory Neuroblastoma
- Conditions
- First Posted Date
- 2003-12-31
- Last Posted Date
- 2010-09-21
- Lead Sponsor
- Fred Hutchinson Cancer Center
- Registration Number
- NCT00006480
- Locations
- 🇺🇸
Cancer Center and Beckman Research Institute, City of Hope, Duarte, California, United States
🇺🇸Fred Hutchinson Cancer Research Center, Seattle, Washington, United States
Gene Therapy in Treating Women With Refractory or Relapsed Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer
- Conditions
- Locations
- 🇺🇸
Human Gene Therapy Research Institute, Des Moines, Iowa, United States
Ganciclovir Plus Arginine Butyrate in Treating Patients With Cancer or Lymphoproliferative Disorders Associated With the Epstein Barr Virus
- Conditions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2013-07-26
- Lead Sponsor
- Boston Medical Center
- Registration Number
- NCT00006340
- Locations
- 🇩🇪
Medizinische Hochschule Hannover, Hannover, Germany
🇺🇸Cancer Research Center at Boston Medical Center, Boston, Massachusetts, United States
🇮🇹Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
Zidovudine Plus Interleukin-2 and Ganciclovir in Treating Patients With AIDS-Related Primary Central Nervous System Lymphoma
- Conditions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2016-02-03
- Lead Sponsor
- AIDS Malignancy Consortium
- Registration Number
- NCT00006264
- Locations
- 🇺🇸
Arthur G. James Cancer Hospital - Ohio State University, Columbus, Ohio, United States
🇺🇸Sylvester Cancer Center, University of Miami, Miami, Florida, United States
Valganciclovir to Prevent Cytomegalovirus Infection in Patients Following Donor Stem Cell Transplantation
- Conditions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2010-05-17
- Lead Sponsor
- Fred Hutchinson Cancer Center
- Target Recruit Count
- 184
- Registration Number
- NCT00016068
- Locations
- 🇺🇸
Mayo Clinic Cancer Center, Rochester, Minnesota, United States
🇺🇸City of Hope Comprehensive Cancer Center, Duarte, California, United States
🇺🇸University of Florida Shands Cancer Center, Gainesville, Florida, United States
Valganciclovir in Congenital CMV Infants
- Conditions
- Interventions
- First Posted Date
- 2002-03-07
- Last Posted Date
- 2011-02-07
- Target Recruit Count
- 24
- Registration Number
- NCT00031434
- Locations
- 🇺🇸
University of Louisville, Louisville, Kentucky, United States
🇺🇸Washington University in St. Louis, Saint Louis, Missouri, United States
🇺🇸Cook Children's Medical Center, Fort Worth, Texas, United States
A Study of Ganciclovir in the Treatment of Cytomegalovirus of the Eyes
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-04
- Target Recruit Count
- 25
- Registration Number
- NCT00001062
- Locations
- 🇺🇸
Johns Hopkins Adult AIDS CRS, Baltimore, Maryland, United States
🇺🇸UCLA CARE Center CRS, Los Angeles, California, United States
🇺🇸Rush Univ. Med. Ctr. ACTG CRS, Chicago, Illinois, United States
Comparison of Two Methods in the Treatment of Cytomegalovirus of the Eyes in Patients With AIDS
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 167
- Registration Number
- NCT00001061
- Locations
- 🇺🇸
USC CRS, Los Angeles, California, United States
🇺🇸Cook County Hosp. CORE Ctr., Chicago, Illinois, United States
🇺🇸Rush Univ. Med. Ctr. ACTG CRS, Chicago, Illinois, United States
Drug Development Updates
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