Pregabalin
- Generic Name
- Pregabalin
- Brand Names
- Lyrica, Pregabalin Accord, Pregabalin Pfizer, Pregabalin Sandoz, Pregabalin Mylan, Pregabalin Zentiva
- Drug Type
- Small Molecule
- Chemical Formula
- C8H17NO2
- CAS Number
- 148553-50-8
- Unique Ingredient Identifier
- 55JG375S6M
- Background
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively defined, there is evidence that pregabalin exerts its effects by bind...
- Indication
Pregabalin is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, fibromyalgia, neuropathic pain associated with spinal cord injury, and as adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older.
- Associated Conditions
- Diabetic Peripheral Neuropathic Pain (DPN), Epilepsies, Fibromyalgia, Generalized Anxiety Disorder, Neuropathic Pain, Partial-Onset Seizures, Peripheral Neuropathic Pain, Peripheral neuropathy, Postherpetic Neuralgia
- Associated Therapies
- -
Efficacy Of Pregabalin In The Treatment Of Pancreatic Cancer Pain. A Randomized Controlled Double-Blind, Parallel Group Study
- First Posted Date
- 2013-01-16
- Last Posted Date
- 2017-10-06
- Lead Sponsor
- Parc de Salut Mar
- Target Recruit Count
- 20
- Registration Number
- NCT01768988
- Locations
- 🇪🇸
Hospital del Mar, Barcelona, Spain
A Study to Compare QUTENZA With Pregabalin for the Treatment of Peripheral Neuropathic Pain (PNP) After 8 Weeks of Treatment
- Conditions
- Interventions
- First Posted Date
- 2012-10-24
- Last Posted Date
- 2018-04-23
- Lead Sponsor
- Astellas Pharma Europe Ltd.
- Target Recruit Count
- 568
- Registration Number
- NCT01713426
- Locations
- 🇹🇷
Site 325 Pamukkale University Medical Faculty Hospital, Denizli, Turkey
🇫🇮Site 163 ORTON Invalidisaatio, Helsinki, Finland
🇬🇷Site 203 Aretaieio/Maginio Hospital, Athens, Greece
Placebo-controlled Safety and Efficacy Study of Pregabalin in Subjects With Post-traumatic Peripheral Neuropathic Pain
- First Posted Date
- 2012-10-05
- Last Posted Date
- 2021-01-28
- Target Recruit Count
- 542
- Registration Number
- NCT01701362
- Locations
- 🇨🇦
Aggarwal and Associates Limited, Brampton, Ontario, Canada
🇺🇸Chicago Anesthesia Associates, Chicago, Illinois, United States
🇺🇸Rehabilitation Institute of Chicago, Chicago, Illinois, United States
Comparing the Efficacy of Pregabalin and Hydroxyzine on the Anxiety Score
- Conditions
- Interventions
- First Posted Date
- 2012-08-30
- Last Posted Date
- 2016-10-11
- Lead Sponsor
- Poitiers University Hospital
- Target Recruit Count
- 306
- Registration Number
- NCT01675986
- Locations
- 🇫🇷
CHU de POITIERS, Poitiers, France
A Clinical Trial to Compare The Pharmacokinetics of A Pregabalin GLARS Tablet 150mg With Immediate Release Formulation and to Assess The Effect of High Fat Diet in Healthy Male Subjects
- First Posted Date
- 2012-07-10
- Last Posted Date
- 2013-01-28
- Lead Sponsor
- GL Pharm Tech Corporation
- Target Recruit Count
- 30
- Registration Number
- NCT01635751
- Locations
- 🇰🇷
The Catholic University of Korea, Seoul St.Mary's Hospital, Seochogu, Seoul, Korea, Republic of
Pregabalin in Preventing Acute Pain Syndrome in Patients Receiving Paclitaxel
- Conditions
- Interventions
- First Posted Date
- 2012-07-10
- Last Posted Date
- 2018-04-06
- Lead Sponsor
- Academic and Community Cancer Research United
- Target Recruit Count
- 46
- Registration Number
- NCT01637077
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
🇺🇸Missouri Valley Cancer Consortium, Omaha, Nebraska, United States
🇺🇸Essentia Health-Duluth CCOP, Duluth, Minnesota, United States
Pre- Versus Post-Incisional Pregabalin for Postoperative Pain Control
- Conditions
- Interventions
- First Posted Date
- 2012-06-07
- Last Posted Date
- 2012-06-07
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Target Recruit Count
- 100
- Registration Number
- NCT01614236
- Locations
- 🇮🇱
Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Pregabalin for Post-craniotomy Pain Control
- First Posted Date
- 2012-06-06
- Last Posted Date
- 2012-06-06
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Target Recruit Count
- 100
- Registration Number
- NCT01612832
Pilot Study Of Pregabalin And Prediction Of Treatment Response In Patients With Postherpetic Neuralgia
- First Posted Date
- 2012-05-22
- Last Posted Date
- 2014-07-08
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 9
- Registration Number
- NCT01603394
- Locations
- 🇿🇦
Pfizer Investigational Site, Paarl, Western Cape, South Africa
Effects of Perioperative Pregabalin for Post-Craniotomy Pain
- Conditions
- Interventions
- First Posted Date
- 2012-05-04
- Last Posted Date
- 2014-02-19
- Lead Sponsor
- Unity Health Toronto
- Registration Number
- NCT01591980
- Locations
- 🇨🇦
St. Michael's Hospital, Toronto, Ontario, Canada
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.