Ramelteon
- Generic Name
- Ramelteon
- Brand Names
- Rozerem
- Drug Type
- Small Molecule
- Chemical Formula
- C16H21NO2
- CAS Number
- 196597-26-9
- Unique Ingredient Identifier
- 901AS54I69
- Background
Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
- Indication
用于失眠症，特别适用于治疗难以入睡型失眠症。
- Associated Conditions
- Insomnia
Long-Term Efficacy of Ramelteon on Endocrine Function in Adult Subjects With Chronic Insomnia
- First Posted Date
- 2008-04-14
- Last Posted Date
- 2012-02-28
- Lead Sponsor
- Takeda
- Target Recruit Count
- 122
- Registration Number
- NCT00656994
Time to Remission of Depressive Symptoms With Combined SSRI and Ramelteon
- Conditions
- Major Depressive DisorderInsomnia
- Interventions
- First Posted Date
- 2008-03-25
- Last Posted Date
- 2019-07-26
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 29
- Registration Number
- NCT00642694
- Locations
- 🇺🇸
University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States
Ramelteon for Treatment of Adult Patients With ADHD-Related Insomnia
- First Posted Date
- 2008-02-25
- Last Posted Date
- 2013-05-24
- Lead Sponsor
- University of Alabama at Birmingham
- Target Recruit Count
- 32
- Registration Number
- NCT00622427
- Locations
- 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
Ramelteon for a Nap Prior to a Night Shift
- First Posted Date
- 2008-01-16
- Last Posted Date
- 2012-10-30
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 11
- Registration Number
- NCT00595075
Ramelteon as an Adjunct Therapy in Non-Diabetic Patients With Schizophrenia
- Conditions
- SchizophreniaSchizoaffective DisorderSchizophreniform Disorders
- Interventions
- Drug: Placebo
- First Posted Date
- 2008-01-16
- Last Posted Date
- 2012-09-13
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 25
- Registration Number
- NCT00595504
- Locations
- 🇺🇸
Freedom Trail Clinic, Boston, Massachusetts, United States
Efficacy of Ramelteon on Speeding Up Sleep in Subjects With Delayed Sleep Phase Syndrome
- Conditions
- Sleep Disorders, Circadian Rhythm
- Interventions
- Drug: Placebo
- First Posted Date
- 2008-01-15
- Last Posted Date
- 2012-02-28
- Lead Sponsor
- Takeda
- Target Recruit Count
- 132
- Registration Number
- NCT00593736
Add-On Ramelteon in Bipolar I Disorder With Clinically Significant Sleep Disturbance
- First Posted Date
- 2008-01-03
- Last Posted Date
- 2013-05-10
- Lead Sponsor
- Lindner Center of HOPE
- Target Recruit Count
- 21
- Registration Number
- NCT00585208
- Locations
- 🇺🇸
The Lindner Center of HOPE, Mason, Ohio, United States
Improving Sleep in Nursing Homes
- First Posted Date
- 2007-12-19
- Last Posted Date
- 2014-08-13
- Lead Sponsor
- Emory University
- Target Recruit Count
- 79
- Registration Number
- NCT00576927
Ramelteon for the Treatment of Insomnia and Mood Stability in Patients With Euthymic Bipolar Disorder
- First Posted Date
- 2007-11-02
- Last Posted Date
- 2014-04-14
- Lead Sponsor
- Lehigh Valley Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT00552760
- Locations
- 🇺🇸
Lehigh Valley Hospital, Department of Psychiatry, Allentown, Pennsylvania, United States
Differential Effects of Zolpidem Versus Ramelteon in Burned Children
- First Posted Date
- 2007-10-04
- Last Posted Date
- 2016-07-27
- Lead Sponsor
- Shriners Hospitals for Children
- Target Recruit Count
- 10
- Registration Number
- NCT00539110
- Locations
- 🇺🇸
Shriners Hospital for Children, Cincinnati, Ohio, United States
Drug Development Updates
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