Estradiol valerate
- Generic Name
- Estradiol valerate
- Brand Names
- Delestrogen, Natazia
- Drug Type
- Small Molecule
- Chemical Formula
- C23H32O3
- CAS Number
- 979-32-8
- Unique Ingredient Identifier
- OKG364O896
- Background
Estradiol Valerate (also known as E2V) is a pro-drug ester of Estradiol, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol acetate therefore has the same downstream effects with...
- Indication
Estradiol valerate is commercially available as an intramuscular injection as the product Delestrogen and is indicated for the treatment of moderate to severe vasomotor symptoms and vulvovaginal atrophy due to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and for the treatment of advanced androgen...
- Associated Conditions
- Advanced Hormone Dependent Prostate Cancer, Heavy Menstrual Bleeding, Hypogonadism, Menopausal Symptoms, Menopause, Menstrual Irregularities, Postmenopausal Osteoporosis, Primary Amenorrhoea, Secondary Amenorrhea, Hypoestrogenism, Moderate Menopausal Vasomotor Symptoms, Moderate menopausal vulvovaginal atrophy, Severe Vasomotor Symptoms Associated With Menopause, Severe menopausal vulvovaginal atrophy
- Associated Therapies
- Hormone Replacement Therapy, Oral Contraceptives
Luteal Phase Support With Estradiol In Poor Responders Undergoing In Vitro Fertilization
- First Posted Date
- 2018-12-27
- Last Posted Date
- 2018-12-27
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 170
- Registration Number
- NCT03788681
- Locations
- 🇪🇬
AinShams university maternity hospital, Cairo, Abbassya, Egypt
Natural Versus Artificial Cycle for Frozen-Thawed Embryo Transfer
- Conditions
- Interventions
- First Posted Date
- 2018-08-22
- Last Posted Date
- 2024-06-28
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Target Recruit Count
- 554
- Registration Number
- NCT03642665
- Locations
- 🇧🇪
UZ Leuven, Leuven, Belgium
Estrogen in the Prevention of Adhesion Reformation
- First Posted Date
- 2018-08-08
- Last Posted Date
- 2021-09-08
- Lead Sponsor
- Fu Xing Hospital, Capital Medical University
- Target Recruit Count
- 186
- Registration Number
- NCT03620929
- Locations
- 🇨🇳
Fuxing hospital, Beijing, Beijing, China
Effectiveness of Estradiol Valerate Pretreatment in Antagonist Protocol for Poor Ovarian Response Patient
- Conditions
- Interventions
- First Posted Date
- 2017-10-03
- Last Posted Date
- 2022-01-11
- Lead Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
- Target Recruit Count
- 552
- Registration Number
- NCT03300518
- Locations
- 🇨🇳
Reproductive & Genetic Hospital of Citic-Xiangya, Changsha, Hunan, China
The Effect of Tamoxifen on Clinical Outcome in Women With Thin Endometrium Undergoing Frozen Thawed Cycle.
- First Posted Date
- 2017-02-23
- Last Posted Date
- 2017-02-24
- Lead Sponsor
- Sun Yat-sen University
- Target Recruit Count
- 100
- Registration Number
- NCT03060304
Sildenafil Citrate in Frozen Embryo Transfer
- First Posted Date
- 2016-07-27
- Last Posted Date
- 2016-07-27
- Lead Sponsor
- Omar Ahmed El Sayed Saad
- Target Recruit Count
- 90
- Registration Number
- NCT02845388
Phytoestrogens as an Alternative to Estradiol in Ovulation Induction in PCOS
- Conditions
- Interventions
- First Posted Date
- 2015-02-02
- Last Posted Date
- 2017-03-24
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 150
- Registration Number
- NCT02352597
HRT Versus MOS for Endometrial Preparation Prior to FET in Non PCOS Patients
- Conditions
- Interventions
- First Posted Date
- 2015-01-05
- Last Posted Date
- 2023-10-30
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 150
- Registration Number
- NCT02330757
- Locations
- 🇪🇬
Fertility Care Unit (FCU) in Mansoura University Hospital, Mansourah, Dakahlia, Egypt
🇪🇬Private fertility care centers, Mansourah, Dakahlia, Egypt
HRT Versus MOS for Endometrial Preparation Prior to FET in PCOS Patients
- Conditions
- Interventions
- First Posted Date
- 2014-10-24
- Last Posted Date
- 2018-10-29
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 126
- Registration Number
- NCT02273791
- Locations
- 🇪🇬
Fertility Care Unit (FCU) in Mansoura University Hospital, Mansourah, Dakahlia, Egypt
🇪🇬Private fertility care centers, Mansourah, Dakahlia, Egypt
Vascular Effect of Estradiol Valerate Versus Placebo Evaluated by Flow-mediated Dilatation of Brachial Artery
- Conditions
- Interventions
- First Posted Date
- 2014-06-12
- Last Posted Date
- 2016-01-15
- Lead Sponsor
- Federal University of Minas Gerais
- Target Recruit Count
- 60
- Registration Number
- NCT02161614
- Locations
- 🇧🇷
Hospital das Clinicas - Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
Drug Development Updates
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