Estradiol valerate
- Generic Name
- Estradiol valerate
- Brand Names
- Delestrogen, Natazia
- Drug Type
- Small Molecule
- Chemical Formula
- C23H32O3
- CAS Number
- 979-32-8
- Unique Ingredient Identifier
- OKG364O896
- Background
Estradiol Valerate (also known as E2V) is a pro-drug ester of Estradiol, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol acetate therefore has the same downstream effects with...
- Indication
Estradiol valerate is commercially available as an intramuscular injection as the product Delestrogen and is indicated for the treatment of moderate to severe vasomotor symptoms and vulvovaginal atrophy due to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and for the treatment of advanced androgen...
- Associated Conditions
- Advanced Hormone Dependent Prostate Cancer, Heavy Menstrual Bleeding, Hypogonadism, Menopausal Symptoms, Menopause, Menstrual Irregularities, Postmenopausal Osteoporosis, Primary Amenorrhoea, Secondary Amenorrhea, Hypoestrogenism, Moderate Menopausal Vasomotor Symptoms, Moderate menopausal vulvovaginal atrophy, Severe Vasomotor Symptoms Associated With Menopause, Severe menopausal vulvovaginal atrophy
- Associated Therapies
- Hormone Replacement Therapy, Oral Contraceptives
Oral Estradiol Valerate Versus Oral Contraceptive Pill in Invitro Fertilization Patients
- Conditions
- Interventions
- First Posted Date
- 2011-12-29
- Last Posted Date
- 2016-03-22
- Lead Sponsor
- IVI Madrid
- Target Recruit Count
- 118
- Registration Number
- NCT01501448
- Locations
- 🇪🇸
IVI Madrid, Madrid, Spain
Programming by Estrogen Treatment in Gonadotropin Releasing Hormone Antagonist Protocol
- First Posted Date
- 2011-08-18
- Last Posted Date
- 2013-12-24
- Lead Sponsor
- Meir Medical Center
- Target Recruit Count
- 63
- Registration Number
- NCT01419353
- Locations
- 🇮🇱
Meir Medical Center, Kfar Saba, Israel
Pretreatment With Estradiol Valerate
- First Posted Date
- 2010-10-11
- Last Posted Date
- 2012-03-28
- Lead Sponsor
- Universitair Ziekenhuis Brussel
- Target Recruit Count
- 80
- Registration Number
- NCT01218386
- Locations
- 🇧🇪
UZ Brussel, Centre for Reproductive Medicine, Brussel, Belgium
Isolated and Associated Effects of Physical Exercise and Estrogen Therapy on Climactercs Women
- Conditions
- Interventions
- First Posted Date
- 2010-05-11
- Last Posted Date
- 2012-06-22
- Lead Sponsor
- University of Sao Paulo General Hospital
- Target Recruit Count
- 62
- Registration Number
- NCT01120665
A Study of Prevention and Treatment of Postmenopausal Osteoporosis in Chinese Women
- First Posted Date
- 2009-03-13
- Last Posted Date
- 2009-03-17
- Lead Sponsor
- Peking Union Medical College
- Target Recruit Count
- 221
- Registration Number
- NCT00860964
A Trial to Evaluate the Efficacy of Low Dose Vaginal Estrogens in the Treatment of Atrophic Vaginitis
- Conditions
- Interventions
- First Posted Date
- 2009-01-01
- Last Posted Date
- 2017-11-13
- Lead Sponsor
- Maire Mac Bride
- Target Recruit Count
- 63
- Registration Number
- NCT00816556
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Effects of Hormone Replacement Therapy on the Serotonergic System and Mood in Postmenopausal Women
- Conditions
- Interventions
- First Posted Date
- 2008-09-19
- Last Posted Date
- 2011-07-22
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 30
- Registration Number
- NCT00755963
- Locations
- 🇦🇹
Medical University of Vienna, Dept. of Psychiatry and Psychotherapy, Vienna, Austria
Drug Development Updates
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