MedPath

Atrial natriuretic peptide

Generic Name
Atrial natriuretic peptide
Drug Type
Biotech
CAS Number
85637-73-6

To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension

Phase 2
Recruiting
Conditions
Difficult to Control Hypertension
Interventions
Other: Placebo Matched control
First Posted Date
2024-04-02
Last Posted Date
2025-04-02
Lead Sponsor
E-Star BioTech, LLC
Target Recruit Count
120
Registration Number
NCT06343298
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Amicis Research Center - Granada Hills, Granada Hills, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Interventional Cardiology Medical Group, West Hills, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Office of Dr. Edward Portnoy MD, Westlake Village, California, United States

and more 18 locations

Enhancing the Natriuretic Peptide System in HFpEF

Phase 1
Conditions
Heart Failure with Preserved Ejection Fraction
Chronic Kidney Diseases
Interventions
Drug: Oral Placebo
Drug: Injection Placebo
First Posted Date
2022-03-15
Last Posted Date
2024-10-04
Lead Sponsor
Horng Chen
Target Recruit Count
60
Registration Number
NCT05279742
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Safety And Tolerability Of Subcutaneous MANP In Difficult To Control/Resistant Hypertensive Subjects

Phase 1
Completed
Conditions
Resistant Hypertension
Difficult to Control Hypertension
Interventions
Drug: Placebo
First Posted Date
2022-02-21
Last Posted Date
2022-11-29
Lead Sponsor
E-Star BioTech, LLC
Target Recruit Count
37
Registration Number
NCT05247528
Locations
๐Ÿ‡บ๐Ÿ‡ธ

USA Clinical Site 01, Tustin, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

USA Clinical Site 04, Decatur, Georgia, United States

๐Ÿ‡บ๐Ÿ‡ธ

USA Clinical Site 05, Owensboro, Kentucky, United States

and more 2 locations

MANP in Hypertension and Metabolic Syndrome

Phase 1
Completed
Conditions
Hypertension
Metabolic Syndrome
Interventions
First Posted Date
2018-12-20
Last Posted Date
2020-11-13
Lead Sponsor
Mayo Clinic
Target Recruit Count
22
Registration Number
NCT03781739
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Mayo Foundation, Rochester, Minnesota, United States

Prevention of Akute Kidney Injury, Hearttransplant, ANP

Phase 3
Completed
Conditions
Acute Kidney Injury
Interventions
Drug: Placebo
First Posted Date
2016-01-27
Last Posted Date
2022-02-09
Lead Sponsor
Sahlgrenska University Hospital, Sweden
Target Recruit Count
86
Registration Number
NCT02665377
Locations
๐Ÿ‡ธ๐Ÿ‡ช

Sahlgrenska sjukhuset, Gothenburg, Sweden

Phase 3 Study of ANP Therapy vs. TMZ for Optic Pathway Glioma

Phase 3
Withdrawn
Conditions
Optic Nerve Glioma
Interventions
First Posted Date
2010-12-15
Last Posted Date
2017-07-26
Lead Sponsor
Burzynski Research Institute
Registration Number
NCT01260103

Carperitide in Acute Respiratory Distress Syndrome (ARDS)

Phase 2
Completed
Conditions
Respiratory Distress Syndrome
First Posted Date
2002-02-01
Last Posted Date
2008-02-20
Lead Sponsor
Suntory Pharmaceutical
Registration Number
NCT00030121
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