Caffeine
- Generic Name
- Caffeine
- Brand Names
- Anacin, Arthriten Inflammatory Pain, Ascomp, Bc Arthritis, Bc Original Formula, Cafcit, Diurex, Dvorah, Esgic, Exaprin, Excedrin, Excedrin Tension Headache, Fioricet, Fioricet With Codeine, Fiorinal, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Midol Complete, Midol Cramps & Bodyaches, Migergot, Norgesic, Norgesic Forte, Orbivan, Orphengesic, Pamprin Max Formula, Peyona, Stanback Headache Powder Reformulated Jan 2011, Trezix, Trianal, Trianal C, Triatec, Triatec-8, Vanatol, Vanatol S, Vanquish, Vivarin, Peyona (previously Nymusa), Gencebok
- Drug Type
- Small Molecule
- Chemical Formula
- C8H10N4O2
- CAS Number
- 58-08-2
- Unique Ingredient Identifier
- 3G6A5W338E
- Background
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine. It can be sourced from coffee beans, but also occurs naturally in various teas and cacao beans, whic...
- Indication
Caffeine is indicated for the short term treatment of apnea of prematurity in infants and off label for the prevention and treatment of bronchopulmonary dysplasia caused by premature birth. In addition, it is indicated in combination with sodium benzoate to treat respiratory depression resulting from an overdose with CNS depressant drugs. Caffeine has a broa...
- Associated Conditions
- Acute Pain, Chronic Lung Disease of Prematurity, Common Cold, Dyspepsia, Fatigue, Fever, Flu caused by Influenza, Headache, Menstrual Pain, Myalgia, Pain, Pain caused by Rheumatism, Primary apnea of premature newborns, Respiratory Depression, Somnolence, Tension Headache, Toothache, Under-eyes Dark Circles, Vascular Headaches, Moderate Pain
- Associated Therapies
- Analgesia, Antacid therapy, Athletic Performance
Caffeine and Cerebrovascular Reactivity
- First Posted Date
- 2021-01-29
- Last Posted Date
- 2022-08-09
- Lead Sponsor
- University of Oklahoma
- Target Recruit Count
- 10
- Registration Number
- NCT04730193
- Locations
- 🇺🇸
Translational GeroScience Laboratory, Oklahoma City, Oklahoma, United States
Estimation of the Effect of Multiple Dose Ritlecitinib (PF-06651600) on the Pharmacokinetics of a Single Dose of Caffeine in Healthy Participants
- First Posted Date
- 2020-12-04
- Last Posted Date
- 2021-03-18
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 12
- Registration Number
- NCT04655040
- Locations
- 🇺🇸
New Haven Clinical Research Unit, New Haven, Connecticut, United States
Drug-drug Interaction Study of KL1333 in Healthy Subjects
- First Posted Date
- 2020-11-25
- Last Posted Date
- 2021-10-20
- Lead Sponsor
- Abliva AB
- Target Recruit Count
- 14
- Registration Number
- NCT04643249
- Locations
- 🇬🇧
Volunteer recruitment center Covance Leeds Covance Leeds, Leeds, United Kingdom
Effect of CAFfeine on Cognition in Alzheimer's Disease
- First Posted Date
- 2020-09-30
- Last Posted Date
- 2022-03-02
- Lead Sponsor
- University Hospital, Lille
- Target Recruit Count
- 248
- Registration Number
- NCT04570085
- Locations
- 🇫🇷
CH Béthune, Béthune, France
🇫🇷CHU Caen, Caen, France
🇫🇷CHU Amiens, Amiens, France
Metformin's Effect on Drug Metabolism in Patients With Type 2 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2020-08-07
- Last Posted Date
- 2022-06-16
- Lead Sponsor
- University of Southern Denmark
- Target Recruit Count
- 10
- Registration Number
- NCT04504045
- Locations
- 🇩🇰
University of Southern Denmark, Odense, Region Of Southern Denmark, Denmark
Caffeine Study for Pain Control Following Total Joint Replacement
- First Posted Date
- 2020-02-21
- Last Posted Date
- 2020-10-19
- Lead Sponsor
- Rothman Institute Orthopaedics
- Target Recruit Count
- 70
- Registration Number
- NCT04280263
- Locations
- 🇺🇸
Rothman Orthopaedics at Egg Harbor Township, Egg Harbor Township, New Jersey, United States
Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4
- Conditions
- Interventions
- First Posted Date
- 2020-01-29
- Last Posted Date
- 2024-08-15
- Lead Sponsor
- R-Pharm International, LLC
- Target Recruit Count
- 17
- Registration Number
- NCT04246762
- Locations
- 🇧🇬
Comac Medical Ltd, Sofia, Bulgaria
🇲🇩ICS ARENSIA Exploratory Medicine SRL, a daughter company of ARENSIA Exploratory Medicine GmbH,Republican Clinical Hospital, Chisinau, Moldova, Republic of
Study to Find Out the Optimal Dose of Caffeine in the Combination Tablet of Naproxen Sodium and Caffeine in Patients Experiencing Moderate to Severe Pain After Having Wisdom Teeth Removed
- Conditions
- Interventions
- First Posted Date
- 2019-10-18
- Last Posted Date
- 2021-09-01
- Lead Sponsor
- Bayer
- Target Recruit Count
- 193
- Registration Number
- NCT04132336
- Locations
- 🇺🇸
JBR Clinical Research, Salt Lake City, Utah, United States
A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or Rosuvastatin
- Conditions
- Interventions
- First Posted Date
- 2019-06-03
- Last Posted Date
- 2019-11-29
- Lead Sponsor
- Kyowa Kirin Co., Ltd.
- Target Recruit Count
- 50
- Registration Number
- NCT03970798
- Locations
- 🇯🇵
Fukuoka Mirai Hospital Clinical Research Center, Fukuoka, Japan
The Effects of a Combination of TeaCrine®, Dynamine, and Caffeine in Law Enforcement
- Conditions
- Interventions
- First Posted Date
- 2019-05-06
- Last Posted Date
- 2021-09-30
- Lead Sponsor
- University of South Carolina
- Target Recruit Count
- 49
- Registration Number
- NCT03937687
- Locations
- 🇺🇸
University of South Carolina Sport Science Lab, Columbia, South Carolina, United States
🇺🇸Rutgers University Center for Health and Human Performance, New Brunswick, New Jersey, United States
Drug Development Updates
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