Furosemide
- Generic Name
- Furosemide
- Brand Names
- Furoscix, Lasix
- Drug Type
- Small Molecule
- Chemical Formula
- C12H11ClN2O5S
- CAS Number
- 54-31-9
- Unique Ingredient Identifier
- 7LXU5N7ZO5
- Background
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It mainly works by inhibiting electrol...
- Indication
Furosemide is indicated for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome, in adults and pediatric patients.
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- Associated Conditions
- Acute Pulmonary Edema, Ascites, Body Fluid Retention, Edema, Hypertension, Mild to Moderate Hypertension, Chest congestion
- Associated Therapies
- -
Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide
- Conditions
- Interventions
- First Posted Date
- 2019-01-11
- Last Posted Date
- 2019-03-22
- Lead Sponsor
- Akebia Therapeutics
- Target Recruit Count
- 62
- Registration Number
- NCT03801759
- Locations
- 🇨🇦
inVentiv Health Clinique Inc., Québec City, Quebec, Canada
Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach
- Conditions
- Interventions
- First Posted Date
- 2018-12-11
- Last Posted Date
- 2023-04-28
- Lead Sponsor
- Washington State University
- Target Recruit Count
- 16
- Registration Number
- NCT03772262
- Locations
- 🇺🇸
Washington State University, Spokane, Washington, United States
FURosemide Stress Test to Predict Need of Renal Replacement THERapy in Ischemic Acute Tubular Necrosis in ICU
- First Posted Date
- 2018-11-06
- Last Posted Date
- 2020-12-16
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 11
- Registration Number
- NCT03731117
- Locations
- 🇫🇷
Hopital Bichat, Paris, France
🇫🇷CH Cote Basque, Bayonne, France
🇫🇷Hopital Saint Louis, Paris, France
An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic
- Conditions
- Interventions
- First Posted Date
- 2018-11-05
- Last Posted Date
- 2021-02-26
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 23
- Registration Number
- NCT03730961
- Locations
- 🇬🇧
Richmond Pharmacology, London, United Kingdom
🇬🇧Glasgow Clinical Research Facility, Glasgow, United Kingdom
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
- Conditions
- Interventions
- Drug: Tranexamic acid (TXA)Drug: HydrocodoneDrug: labetalolDrug: metforminDrug: nifedipineDrug: oxycodoneDrug: clindamycinDrug: azithromycinDrug: escitalopramDrug: sertralineDrug: CiprofloxacinDrug: ondansetronDrug: DoxycyclineDrug: LevofloxacinDrug: MethylphenidateDrug: CitalopramDrug: SumatriptanDrug: CyclobenzaprineDrug: FurosemideDrug: RosuvastatinDrug: GabapentinDrug: HydrochlorothiazideDrug: HydroxyureaDrug: TrazodoneDrug: TopiramateDrug: ValganciclovirDrug: RemdesivirDrug: VenlafaxineDrug: VerapamilDrug: FluvoxamineDrug: AnakinraDrug: TocilizumabDrug: AmoxicillinDrug: BupropionDrug: BuprenorphineDrug: LevetiracetamDrug: ParoxetineDrug: Duloxetine
- First Posted Date
- 2018-04-27
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Duke University
- Target Recruit Count
- 1600
- Registration Number
- NCT03511118
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
🇺🇸Ann and Robert H. Lurie Childrens Hospital of Chicago, Chicago, Illinois, United States
🇺🇸Loma Linda University Health, Loma Linda, California, United States
Furosemide and Coarctation Surgery Lung Complications
- First Posted Date
- 2017-12-07
- Last Posted Date
- 2017-12-27
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 56
- Registration Number
- NCT03364842
- Locations
- 🇪🇬
Cairo university, Cairo, Egypt
Treatment of Post-Operative Sinonasal Polyposis With Topical Furosemide
- First Posted Date
- 2017-12-05
- Last Posted Date
- 2023-08-30
- Lead Sponsor
- Thomas Jefferson University
- Target Recruit Count
- 18
- Registration Number
- NCT03362515
- Locations
- 🇺🇸
Thomas Jefferson University Department of Otolaryngology, Philadelphia, Pennsylvania, United States
This Study Tests the Effect of Certain Medicines on the Transport of Other Medicines in the Body of Healthy Men
- Conditions
- Interventions
- First Posted Date
- 2017-10-11
- Last Posted Date
- 2023-11-07
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 45
- Registration Number
- NCT03307252
- Locations
- 🇩🇪
CTC North GmbH & Co. KG, Hamburg, Hamburg, Germany
TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure
- First Posted Date
- 2017-09-28
- Last Posted Date
- 2022-08-19
- Lead Sponsor
- Duke University
- Target Recruit Count
- 2859
- Registration Number
- NCT03296813
- Locations
- 🇺🇸
Weill Cornell Medical College, New York, New York, United States
🇺🇸VA Medical Center/University of Maryland, Baltimore, Maryland, United States
🇺🇸Drexel University College of Medicine, Philadelphia, Pennsylvania, United States
SGLT2 Inhibition in Combination With Diuretics in Heart Failure
- Conditions
- Interventions
- First Posted Date
- 2017-07-21
- Last Posted Date
- 2021-06-30
- Lead Sponsor
- University of Dundee
- Target Recruit Count
- 23
- Registration Number
- NCT03226457
- Locations
- 🇬🇧
University of Dundee, Ninewells Hospital and Medical School, Dundee, Angus, United Kingdom
Drug Development Updates
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