Citalopram

Generic Name
Citalopram
Brand Names
Celexa, Ctp
Drug Type
Small Molecule
Chemical Formula
C20H21FN2O
CAS Number
59729-33-8
Unique Ingredient Identifier
0DHU5B8D6V
Background

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. Citalopram enhances serotonergic transmission through the i...

Indication

Citalopram is approved by the FDA for treating adults with major depressive disorder. It has also been used off-label to treat various diseases, including but not limited to sexual dysfunction, ethanol abuse, psychiatric conditions such as obsessive-compulsive disorder (OCD), social anxiety disorder, panic disorder, and diabetic neuropathy.

Associated Conditions
Alcohol Abuse, Anorexia Nervosa (AN), Binge Eating Disorder (BED), Bulimia Nervosa, Depression, Diabetic Neuropathies, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premature Ejaculation, Premenstrual Dysphoric Disorder (PMDD), Separation Anxiety Disorder, Social Anxiety Disorder (SAD)
Associated Therapies
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Anxiety and Recurrent Abdominal Pain in Children

Phase 2
Completed
Conditions
Interventions
First Posted Date
2009-08-19
Last Posted Date
2020-06-11
Lead Sponsor
John V. Campo, M.D.
Target Recruit Count
81
Registration Number
NCT00962039
Locations
🇺🇸

The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States

Seroquel Alone Versus Seroquel With an SSRI for Depression With Psychotic Symptoms

First Posted Date
2009-08-10
Last Posted Date
2017-04-20
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
32
Registration Number
NCT00955474
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Citalopram for Agitation in Alzheimer's Disease

Phase 3
Completed
Conditions
Interventions
First Posted Date
2009-05-12
Last Posted Date
2014-06-27
Lead Sponsor
JHSPH Center for Clinical Trials
Target Recruit Count
186
Registration Number
NCT00898807
Locations
🇺🇸

Monroe Community Hospital, Rochester, New York, United States

🇺🇸

VA Palo Alto Health Care System, Palo Alto, California, United States

🇺🇸

University of Southern California Keck School of Medicine Memory and Aging Center, Los Angeles, California, United States

and more 5 locations

Functional MRI Before and After Treatment for Depression

Not Applicable
Terminated
Conditions
Interventions
First Posted Date
2009-05-11
Last Posted Date
2017-10-13
Lead Sponsor
Stanford University
Target Recruit Count
31
Registration Number
NCT00896441
Locations
🇺🇸

Stanford University School of Medicine, Stanford, California, United States

Effect of Add-on Citalopram to Risperidone on Negative Symptoms in Schizophrenia

First Posted Date
2009-05-05
Last Posted Date
2009-05-05
Lead Sponsor
National Institute of Mental Health and Neuro Sciences, India
Target Recruit Count
48
Registration Number
NCT00893256
Locations
🇮🇳

National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India

Pharmacokinetics of Citalopram in Patients With Short Bowel Syndrome

Not Applicable
Withdrawn
Conditions
Interventions
First Posted Date
2009-04-06
Last Posted Date
2023-08-14
Lead Sponsor
University of Nebraska
Registration Number
NCT00876226

Comparing Treatments for Self-Injury and Suicidal Behavior in People With Borderline Personality Disorder

First Posted Date
2009-02-03
Last Posted Date
2017-08-18
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
84
Registration Number
NCT00834834
Locations
🇺🇸

New York State Psychiatric Institute, New York, New York, United States

Brain Effects of Escitalopram and Citalopram Using fMRI

First Posted Date
2009-01-21
Last Posted Date
2015-07-14
Lead Sponsor
Michael Henry, MD
Target Recruit Count
27
Registration Number
NCT00825825
Locations
🇺🇸

Steward St. Elizabeth's Medical Center, Boston, Massachusetts, United States

Comparison of the Pharmacokinetics of Two Generic Antidepressants and Their Respective Brand Preparations

First Posted Date
2008-05-12
Last Posted Date
2009-02-11
Lead Sponsor
University of Ottawa
Target Recruit Count
18
Registration Number
NCT00676039
Locations
🇨🇦

University of Ottawa, Institute of Mental Health Research, Ottawa, Ontario, Canada

Pipamperone/Citalopram (PipCit)Versus Citalopram in the Treatment of Major Depressive Disorder(MDD)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2008-05-06
Last Posted Date
2011-05-02
Lead Sponsor
PharmaNeuroBoost N.V.
Target Recruit Count
165
Registration Number
NCT00672659
Locations
🇬🇧

CPSResearch, Glasgow, Scotland, United Kingdom

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