Citalopram

Generic Name
Citalopram
Brand Names
Celexa, Ctp
Drug Type
Small Molecule
Chemical Formula
C20H21FN2O
CAS Number
59729-33-8
Unique Ingredient Identifier
0DHU5B8D6V
Background

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. Citalopram enhances serotonergic transmission through the i...

Indication

Citalopram is approved by the FDA for treating adults with major depressive disorder. It has also been used off-label to treat various diseases, including but not limited to sexual dysfunction, ethanol abuse, psychiatric conditions such as obsessive-compulsive disorder (OCD), social anxiety disorder, panic disorder, and diabetic neuropathy.

Associated Conditions
Alcohol Abuse, Anorexia Nervosa (AN), Binge Eating Disorder (BED), Bulimia Nervosa, Depression, Diabetic Neuropathies, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premature Ejaculation, Premenstrual Dysphoric Disorder (PMDD), Separation Anxiety Disorder, Social Anxiety Disorder (SAD)
Associated Therapies
-

A Study Comparing Duloxetine to Other Antidepressants in the Treatment of Severe Depression

First Posted Date
2008-04-25
Last Posted Date
2010-06-15
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
750
Registration Number
NCT00666757
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Brown Deer, Wisconsin, United States

Functional MRI Evaluation of the Effect of Citalopram in Autism Spectrum Disorders

Phase 1
Completed
Conditions
Interventions
First Posted Date
2008-02-07
Last Posted Date
2012-10-08
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
12
Registration Number
NCT00609531
Locations
🇺🇸

UNC-Chapel Hill, Chapel Hill, North Carolina, United States

Effectiveness of Methylphenidate in Improving Cognition and Function in Older Adults With Depression

First Posted Date
2008-01-28
Last Posted Date
2018-01-11
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
181
Registration Number
NCT00602290
Locations
🇺🇸

UCLA Semel Institute - Neuropsychiatric Institute (NPI), Los Angeles, California, United States

Dementia Antipsychotics And Antidepressants Discontinuation Study

First Posted Date
2008-01-15
Last Posted Date
2011-02-23
Lead Sponsor
Sykehuset Innlandet HF
Target Recruit Count
149
Registration Number
NCT00594269
Locations
🇳🇴

Sykehuset Innlandet HF, Reinsvoll, Oppland, Norway

🇳🇴

Diakonihjemmets Hospital, Oslo, Norway

🇳🇴

Ullevaal University Hospital, Oslo, Norway

and more 5 locations

Study Evaluating a Combined Administration of Lecozotan SR and Citalopram in Young Healthy Subjects

Phase 1
Completed
Conditions
First Posted Date
2007-10-03
Last Posted Date
2007-12-11
Lead Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Target Recruit Count
40
Registration Number
NCT00538889

Citalopram in Irritable Bowel Syndrome

Phase 2
Completed
Conditions
Interventions
First Posted Date
2007-05-22
Last Posted Date
2017-04-17
Lead Sponsor
Stanford University
Target Recruit Count
54
Registration Number
NCT00477165
Locations
🇺🇸

UCSF, San Francisco, California, United States

Discontinuation of Antipsychotics and Antidepressants Among Patients With BPSD

First Posted Date
2007-02-09
Last Posted Date
2007-08-24
Lead Sponsor
Sykehuset Innlandet HF
Target Recruit Count
24
Registration Number
NCT00433121
Locations
🇳🇴

Sykehuset Innlandet HF - Sanderud, Ottestad, Oppland, Norway

Serotonergic Function and Behavioural and Psychological Symptoms of Frontotemporal Dementia

Phase 4
Completed
Conditions
First Posted Date
2006-09-14
Last Posted Date
2017-05-05
Lead Sponsor
Sunnybrook Health Sciences Centre
Target Recruit Count
22
Registration Number
NCT00376051
Locations
🇨🇦

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

🇨🇦

The Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada

STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol Abuse

First Posted Date
2006-08-29
Last Posted Date
2014-05-09
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
674
Registration Number
NCT00369746
Locations
🇺🇸

New York State Psychiatric Institute, New York, New York, United States

Efficacy of Seroquel SR in Combination With an Antidepressant in Treatment of Major Depressive Disorder

Phase 3
Completed
Conditions
First Posted Date
2006-07-13
Last Posted Date
2011-01-26
Lead Sponsor
AstraZeneca
Target Recruit Count
494
Registration Number
NCT00351910
Locations
🇸🇪

Research Site, Uppsala, Sweden

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