Overview
Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Proline is sometimes called an imino acid, although the IUPAC definition of an imine requires a carbon-nitrogen double bond. Proline is a non-essential amino acid that is synthesized from glutamic acid. It is an essential component of collagen and is important for proper functioning of joints and tendons.
Indication
L-Proline is extremely important for the proper functioning of joints and tendons and also helps maintain and strengthen heart muscles.
Associated Conditions
No associated conditions information available.
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
---|---|---|---|---|---|
2025/05/06 | Not Applicable | Recruiting | |||
2024/10/08 | Not Applicable | Not yet recruiting | |||
2024/02/05 | N/A | Completed | Ondokuz Mayıs University | ||
2023/10/24 | Phase 1 | Recruiting | |||
2023/10/13 | Phase 1 | Completed | |||
2023/03/28 | Not Applicable | Active, not recruiting | |||
2021/05/11 | Phase 3 | Recruiting | Children's Cancer Group, China | ||
2020/12/21 | Not Applicable | Completed | |||
2018/11/13 | Phase 4 | Terminated | |||
2016/07/01 | Phase 1 | UNKNOWN |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
---|---|---|---|---|---|
Baxter Healthcare Corporation | 0338-0184 | INTRAVENOUS | 544 mg in 100 mL | 4/13/2021 | |
Baxter Healthcare Company | 0338-0210 | INTRAVENOUS | 544 mg in 100 mL | 9/21/2020 | |
Baxter Healthcare Corporation | 0338-0210 | INTRAVENOUS | 544 mg in 100 mL | 9/21/2020 | |
Baxter Healthcare Corporation | 0338-1089 | INTRAVENOUS | 289 mg in 100 mL | 4/13/2021 | |
Baxter Healthcare Corporation | 0338-1099 | INTRAVENOUS | 340 mg in 100 mL | 4/13/2021 | |
ICU Medical Inc. | 0990-7171 | INTRAVENOUS | 1083 mg in 100 mL | 5/4/2022 | |
Baxter Healthcare Corporation | 0338-0194 | INTRAVENOUS | 544 mg in 100 mL | 4/13/2021 | |
Baxter Healthcare Company | 0338-1147 | INTRAVENOUS | 340 mg in 100 mL | 9/21/2020 | |
Baxter Healthcare Corporation | 0338-1147 | INTRAVENOUS | 340 mg in 100 mL | 9/21/2020 | |
Baxter Healthcare Company | 0338-1142 | INTRAVENOUS | 187 mg in 100 mL | 9/21/2020 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
---|---|---|---|
No EMA approvals found for this drug. |
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
---|---|---|---|---|---|
TROPHAMINE INJECTION 10% | SIN07846P | INJECTION | 0.68 g/100 ml | 9/12/1994 | |
SYNTHAMIN 17 WITHOUT ELECTROLYTES 10% AMINO ACID INTRAVENOUS INFUSION | SIN09992P | INJECTION | 6.80 g/l | 9/15/1998 | |
OLICLINOMEL N7-1000 E EMULSION FOR INFUSION | SIN12539P | EMULSION | 2.72 g/l | 5/6/2004 | |
AMINOPLASMAL B.BRAUN 10% E SOLUTION FOR INFUSION | SIN15411P | INFUSION, SOLUTION | 5.50g/1000ml | 1/23/2018 | |
GLAMIN SOLUTION FOR INFUSION | SIN09906P | INJECTION | 6.8 g/1000 ml | 7/27/1998 | |
SmofKabiven Peripheral Emulsion for Infusion | SIN14287P | INJECTION, EMULSION | 11.2g /1000ml | 1/8/2013 | |
PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION | SIN10252P | INJECTION | 3 g/l | 9/23/1998 | |
AMINOVEN SOLUTION FOR INFUSION 5% | SIN11682P | INJECTION | 5.600 g/1000 ml | 9/25/2001 | |
NUTRIFLEX® OMEGA SPECIAL EMULSION FOR INFUSION | SIN15469P | INJECTION, EMULSION | 4.760g/1000ml | 4/23/2018 | |
PERIOLIMEL N4E Emulsion for Infusion | SIN16888P | EMULSION | 1.51g/L | 10/20/2023 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
---|---|---|---|---|---|
No NMPA approvals found for this drug. |
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
---|---|---|---|---|---|
VAMINOLACT I.V. SOLUTION | N/A | N/A | N/A | 10/14/1992 | |
NUTRIFLEX OMEGA SPECIAL EMULSION FOR INFUSION | N/A | N/A | N/A | 1/11/2012 | |
OLIMEL N9E EMULSION FOR INFUSION | N/A | N/A | N/A | 10/24/2013 | |
NUTRIFLEX OMEGA PLUS EMULSION FOR INFUSION | N/A | N/A | N/A | 1/11/2012 | |
NUTRINEAL PD-4 W/1.1% AA PERITONEAL DIAL SOLN | N/A | N/A | N/A | 12/31/2003 | |
NUTRINEAL PD4 SOLUTION | N/A | N/A | N/A | 9/9/1999 |
TGA Drug Approvals
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
---|---|---|---|---|---|
4.25% TRAVASOL AMINO ACID INJECTION WITH ELECTROLYTES IN 10% DEXTROSE | baxter corporation clintec nutrition division | N/A | Solution - Intravenous | 289 MG / 100 ML | 12/31/1996 |
4.25% TRAVASOL AMINO ACID INJECTION WITHOUT ELECTRLYTES IN 10% DEXTROSE | baxter corporation clintec nutrition division | N/A | Solution - Intravenous | 289 MG / 100 ML | 12/31/1996 |
2.75%TRAVASOL AMINO ACID INJ.W.ELEC.W.5%DEX. | clintec nutrition company | 02143240 | Liquid - Intravenous | 187 MG / 100 ML | 12/31/1996 |
4.25%TRAVASOL AMINO ACID INJ.W.ELECW.5%DEX. | clintec nutrition company | 02143224 | Liquid - Intravenous | 289 MG / 100 ML | 12/31/1996 |
5% TRAVASOL AMINO ACID INJECTION WITHOUT ELECTROLYTES IN 25% DEXTROSE | baxter corporation clintec nutrition division | 02142244 | Solution - Intravenous | 340 MG / 100 ML | 12/31/1996 |
2.5% TRAVASOL AMINO ACID INJECTION WITH ELECTROLYTES IN 10% DEXTROSE CLINIMIX | baxter corporation clintec nutrition division | 02013975 | Solution - Intravenous | 105 MG / 100 ML | 12/31/1993 |
CLINIMIX E | baxter corporation | 02013967 | Solution - Intravenous | 210 MG / 100 ML | 12/31/1993 |
5% TRAVASOL AMINO ACID INJECTION WITHOUT ELECTROLYTES IN 20% DEXTROSE | baxter corporation clintec nutrition division | 02142252 | Solution - Intravenous | 340 MG / 100 ML | 12/31/1996 |
5% TRAVASOL AMINO ACID INJECTION WITH ELECTROLYTES IN 20% DEXTROSE | baxter corporation clintec nutrition division | 02142368 | Solution - Intravenous | 340 MG / 100 ML | 12/31/1996 |
4.25% TRAVASOL AMINO ACID INJECTION WITHOUT ELECTROLYTES IN 25% DEXTROSE | baxter corporation clintec nutrition division | 02142295 | Solution - Intravenous | 289 MG / 100 ML | 12/31/1996 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
---|---|---|---|---|---|
No CIMA AEMPS (Spain) approvals found for this drug. |
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
---|---|---|---|---|---|
No Philippines FDA approvals found for this drug. |
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
---|---|---|---|---|---|
No Saudi SFDA approvals found for this drug. |
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
---|---|---|---|---|---|
No Malaysia NPRA approvals found for this drug. |
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
---|---|---|---|---|---|
No UK EMC drug information found for this drug. |
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