Riboflavin
- Generic Name
- Riboflavin
- Brand Names
- Alertonic, Concept Ob, Irospan 24/6 Kit, Mvc-fluoride, Natafort, Pregvit, Tandem Plus, Vitafol-one
- Drug Type
- Small Molecule
- Chemical Formula
- C17H20N4O6
- CAS Number
- 83-88-5
- Unique Ingredient Identifier
- TLM2976OFR
- Background
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.
- Indication
For the treatment of ariboflavinosis (vitamin B2 deficiency).
- Associated Conditions
- Ariboflavinosis, Beriberi, Constipation, Functional Gastrointestinal Disorders (FGID), Joint Pain, Metabolic cardiomyopathy, Migraine, Myalgia, Neuropathic Pain, Peripheral neuritis, Peripheral paralysis, Vitamin B complex deficiency, Vitamin B1 deficiency, Vitamin Deficiency, Wernicke's encephalopathy
- Associated Therapies
- Dietary and Nutritional Therapies, Nutritional supplementation, Vitamin supplementation, Dietary supplementation
Adapted Fluence Settings for Corneal Collagen Cross-linking in Mild to Moderate Progressive Keratoconus
- Conditions
- Keratoconus
- Interventions
- Radiation: adjusted corneal collagen cross-linkingRadiation: accelerated corneal collagen cross-linkingProcedure: epithelial debridement
- First Posted Date
- 2015-07-23
- Last Posted Date
- 2015-07-23
- Lead Sponsor
- Tehran University of Medical Sciences
- Target Recruit Count
- 40
- Registration Number
- NCT02507362
- Locations
- š®š·
Farabi eye hospital, Tehran, Iran, Islamic Republic of
Standard Corneal Collagen Crosslinking Versus Transepithelial Corneal Crosslinking by Iontophoresis of Riboflavin
- Conditions
- Keratoconus
- Interventions
- Procedure: iontophoresis of riboflavinProcedure: epithelium-offProcedure: Corneal collagen crosslinkingDevice: galvanizator, Potok-1Drug: DextralinkDevice: UFalink
- First Posted Date
- 2015-05-29
- Last Posted Date
- 2015-05-29
- Lead Sponsor
- Ufa Eye Research Institute
- Target Recruit Count
- 126
- Registration Number
- NCT02456961
Standard Versus Transepithelial Corneal Crosslinking
- Conditions
- Keratoconus
- Interventions
- First Posted Date
- 2015-01-28
- Last Posted Date
- 2015-01-28
- Lead Sponsor
- Nienke Soeters
- Target Recruit Count
- 61
- Registration Number
- NCT02349165
- Locations
- š³š±
University Medical Center Utrecht, Utrecht, Netherlands
Ramelteon in the Prevention of Post-operative Delirium
- Conditions
- Cognitive DisordersDelayed Emergence From AnesthesiaDeliriumDelirium, Dementia, Amnestic, Cognitive Disorders
- Interventions
- First Posted Date
- 2014-12-24
- Last Posted Date
- 2020-06-30
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 80
- Registration Number
- NCT02324153
- Locations
- šŗšø
Johns Hopkins Bayview Medical Center, Baltimore, Maryland, United States
Evaluation of a Compliance Marker in Prescription Opioid Abusers With Chronic Pain
- Conditions
- ComplianceChronic Pain
- Interventions
- First Posted Date
- 2014-10-28
- Last Posted Date
- 2017-02-10
- Lead Sponsor
- Georgetown University
- Registration Number
- NCT02276989
- Locations
- šŗšø
Georgetown University, Washington, District of Columbia, United States
The Impact of Riboflavin on the Severity and Duration of Sports Related Concussion
- First Posted Date
- 2014-09-09
- Last Posted Date
- 2017-08-11
- Lead Sponsor
- University of Virginia
- Target Recruit Count
- 248
- Registration Number
- NCT02235337
- Locations
- šŗšø
James Madison University, Harrisonburg, Virginia, United States
šŗšøUniversity of Virginia, Charlottesville, Virginia, United States
Safety and Effectiveness of the UV-X System for Corneal Collagen Cross-Linking in Eyes With Refractory Corneal Infection
- Conditions
- Corneal Ulcers
- Interventions
- Other: UV-Xā¢ Illumination System
- First Posted Date
- 2014-02-21
- Last Posted Date
- 2023-02-09
- Lead Sponsor
- Stephen Trokel
- Target Recruit Count
- 6
- Registration Number
- NCT02068430
- Locations
- šŗšø
Harkness Eye Institute Columbia University, New York, New York, United States
Study of the Safety and Effectiveness of Collagen Cross-Linking at an Irradiance of 9 mW/cm2 and 18 mW/cm2
- Conditions
- KeratoconusCorneal Ectasia
- Interventions
- First Posted Date
- 2013-12-12
- Last Posted Date
- 2015-12-14
- Lead Sponsor
- Robert Mack, M.D.
- Target Recruit Count
- 100
- Registration Number
- NCT02009709
- Locations
- šŗšø
Mack Eye Center, Hoffman Estates, Illinois, United States
Safety and Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus
- Conditions
- Keratoconus
- Interventions
- First Posted Date
- 2013-10-31
- Last Posted Date
- 2021-04-26
- Lead Sponsor
- Glaukos Corporation
- Target Recruit Count
- 92
- Registration Number
- NCT01972854
- Locations
- šŗšø
Focal Point Vision, San Antonio, Texas, United States
šŗšøGordon -Weiss Vision Institute, San Diego, California, United States
šŗšøUPMC Eye Center, Pittsburgh, Pennsylvania, United States
Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism
- Conditions
- HyperopiaHyperopic Astigmatism
- Interventions
- Device: UVA Irradiation (30 mW/cm2 for 2 minutes continuous UVA)Device: UVA Irradiation (30 mW/cm2 for 3 minutes pulsed UVA with an on/off cycle of 2 seconds UVA on/1 second UVA off)Procedure: Laser-assisted in situ keratomileusis
- First Posted Date
- 2013-07-09
- Last Posted Date
- 2021-04-26
- Lead Sponsor
- Glaukos Corporation
- Target Recruit Count
- 2
- Registration Number
- NCT01893359
- Locations
- šŗšø
Gordon -Weiss-Schanzlin Vision Institute, San Diego, California, United States
šŗšøSee Clearly Vision, McLean, Virginia, United States
šŗšøOphthalmic Consultants of Boston, Waltham, Massachusetts, United States
Drug Development Updates
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