Hypromellose
- Generic Name
- Hypromellose
- Brand Names
- Bion Tears, Clear Eyes Complete, Genteal, Genteal Tears, Genteal Tears Mild, Gonak, Goniovisc, Isopto Alkaline, Nature's Tears, Systane, Tears Lubricant, Tears Naturale, Tears Renewed
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- 9004-65-3
- Unique Ingredient Identifier
- 3NXW29V3WO
- Background
Hypromellose, or hydroxypropyl methylcellulose (HPMC) , is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations . It is a common...
- Indication
Used as an ophthalmic protectant and lubricant, in artificial tears, and as a diagnostic aid (contact lens procedures; gonioscopy).
- Associated Conditions
- Dry Eyes, Ocular Discomfort, Ocular Irritation
- Associated Therapies
- -
Interval Intraocular Pressure in Intravitreal Injection Study
- Conditions
- Interventions
- First Posted Date
- 2021-04-30
- Last Posted Date
- 2021-04-30
- Lead Sponsor
- The University of Hong Kong
- Target Recruit Count
- 64
- Registration Number
- NCT04868175
- Locations
- 🇭🇰
HKSDS Program, Hong Kong, Hong Kong
Efficacy Study of Ketorolac and HPMC to Treat Dry Eye
- First Posted Date
- 2018-10-02
- Last Posted Date
- 2024-04-24
- Lead Sponsor
- ORA, Inc.
- Registration Number
- NCT03693183
- Locations
- 🇺🇸
Ophthalmic Reserach Associates, Andover, Massachusetts, United States
Vapocoolant Spray Used Prior to Intravenous (IV) Insertions
- First Posted Date
- 2017-02-16
- Last Posted Date
- 2018-10-03
- Lead Sponsor
- Aultman Health Foundation
- Target Recruit Count
- 30
- Registration Number
- NCT03054740
- Locations
- 🇺🇸
Aultman Health Foundation, Canton, Ohio, United States
Efficacy and Safety of PRO-148 Versus Systane®, in Patients With Mild to Moderate Dry Eye
- First Posted Date
- 2012-08-06
- Last Posted Date
- 2017-12-15
- Lead Sponsor
- Laboratorios Sophia S.A de C.V.
- Target Recruit Count
- 183
- Registration Number
- NCT01657253
- Locations
- 🇲🇽
Consultorio privado, Guadalajara, Jalisco, Mexico
Evaluation of Ocular Comfort With ISTA Tears vs Systane
- First Posted Date
- 2012-07-26
- Last Posted Date
- 2024-10-08
- Lead Sponsor
- Bausch & Lomb Incorporated
- Target Recruit Count
- 35
- Registration Number
- NCT01650584
- Locations
- 🇺🇸
ISTA Pharmaceuticals, Inc., Irvine, California, United States
Efficacy of FreshKote and Systane for the Treatment of Dry Eye and Improvement of Osmolarity
- First Posted Date
- 2011-06-30
- Last Posted Date
- 2012-06-14
- Lead Sponsor
- Innovative Medical
- Target Recruit Count
- 40
- Registration Number
- NCT01386073
- Locations
- 🇺🇸
Jackson Eye, S.C, Lake Villa, Illinois, United States
🇺🇸Pepose Vision Institute, Chesterfield, Missouri, United States
Hydroxypropylmethylcellulose 0.3% and Sodium Hyaluronate 0.18% for Ocular Surface Disease in Glaucoma
- Conditions
- Interventions
- First Posted Date
- 2011-01-27
- Last Posted Date
- 2011-01-27
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 120
- Registration Number
- NCT01284439
- Locations
- 🇹🇭
Department of Ophthalmology , Siriraj Hospital, Bangkok, Thailand
The Effects of BAK on the Blood Aqueous Barrier of Pseudophakic Patients
- Conditions
- Interventions
- First Posted Date
- 2011-01-20
- Last Posted Date
- 2012-07-18
- Lead Sponsor
- University of Campinas, Brazil
- Target Recruit Count
- 44
- Registration Number
- NCT01280110
- Locations
- 🇧🇷
Department of Ophthalmology, University of Campinas, Campinas, SP, Brazil
Efficacy of PEG-400 and Systane Artificial Tears (Alcon) on Quality of Vision
- First Posted Date
- 2008-03-03
- Last Posted Date
- 2008-11-24
- Lead Sponsor
- Bp Consulting, Inc
- Target Recruit Count
- 40
- Registration Number
- NCT00627302
- Locations
- 🇺🇸
Ophthalmic Consultants of long Island, Rockville Centre, New York, United States
Bilateral, Masked Comparison of PEG-400 Based Artificial Tear vs. Systane for Dry Eye Signs, Symptoms & Refractive Regression Associated With Myopic Laser in Situ Keratomilieusis (LASIK).
- Conditions
- Interventions
- First Posted Date
- 2008-02-22
- Last Posted Date
- 2009-09-21
- Lead Sponsor
- Bp Consulting, Inc
- Target Recruit Count
- 100
- Registration Number
- NCT00620893
- Locations
- 🇺🇸
Weill Cornell Medical Center, New York, New York, United States
Drug Development Updates
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