MedPath

IS-10506

Generic Name
IS-10506

Efficacy and Safety of Oral Probiotics on Ocular Symptoms and Gut Microbiome of Children with Vernal Keratoconjunctivitis

Phase 1
Not yet recruiting
Conditions
Probiotic
Ocular Surface Disease
Ocular Diseases
Ocular Dryness
Gut Microbiome Dysbiosis
Gut -microbiota
Interventions
Drug: Placebo Drug
First Posted Date
2025-01-27
Last Posted Date
2025-01-27
Lead Sponsor
Mohsen Pourazizi
Target Recruit Count
32
Registration Number
NCT06793514

The Effect of Probiotic and Zinc Supplementation in Patients With Gastroesophageal Reflux Disease

Phase 4
Not yet recruiting
Conditions
Gastro-oesophageal Reflux Disease
Interventions
Drug: PPI (proton pump inhibitor)
First Posted Date
2024-10-29
Last Posted Date
2024-10-29
Lead Sponsor
Ain Shams University
Target Recruit Count
120
Registration Number
NCT06664008

Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and Knee

Phase 4
Not yet recruiting
Conditions
Prosthetic-joint Infection
Dysbiosis
Interventions
Other: Standard of care
First Posted Date
2024-10-15
Last Posted Date
2025-02-25
Lead Sponsor
Boston Medical Center
Target Recruit Count
152
Registration Number
NCT06636669
Locations
🇺🇸

Boston Medical Center, Orthopedic Surgery, Boston, Massachusetts, United States

🇺🇸

New York University Langone Orthopedics, New York, New York, United States

Effect of Probiotics Among Overweight and Obese Saudi Adults

Phase 3
Completed
Conditions
Obesity
Adult
Interventions
Dietary Supplement: Placebo
First Posted Date
2022-12-28
Last Posted Date
2023-10-04
Lead Sponsor
King Saud University
Target Recruit Count
90
Registration Number
NCT05667038
Locations
🇸🇦

King Saud University, Riyadh, Saudi Arabia

Probiotic For the Improvement of Environmental Enteropathy in Pregnant Women in Senegal

Phase 2
Recruiting
Conditions
Environmental Enteric Dysfunction
Interventions
Device: CapScan®
Drug: Placebo
First Posted Date
2022-08-15
Last Posted Date
2025-05-13
Lead Sponsor
Institut Pasteur de Dakar
Target Recruit Count
76
Registration Number
NCT05501470
Locations
🇸🇳

Centre de santé de Wakhinane, Guédiawaye, Dakar, Senegal

Probiotic in Treatment of Adult Patients With Drug-resistant Epilepsy

Phase 4
Completed
Conditions
Epilepsy
Treatment
Interventions
First Posted Date
2021-12-16
Last Posted Date
2022-01-11
Lead Sponsor
Mazandaran University of Medical Sciences
Target Recruit Count
42
Registration Number
NCT05160350
Locations
🇮🇷

Bu Ali Sina Hospital, Sari, Mazandaran, Iran, Islamic Republic of

Effects of Probiotics on the Gut Microbiome and Immune System in Operable Stage I-III Breast or Lung Cancer

Early Phase 1
Completed
Conditions
Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Stage II Lung Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Breast Adenocarcinoma
Stage I Lung Cancer AJCC v8
Stage III Lung Cancer AJCC v8
Interventions
Procedure: Biopsy
Procedure: Biospecimen Collection
Procedure: Therapeutic Conventional Surgery
First Posted Date
2021-04-23
Last Posted Date
2023-04-21
Lead Sponsor
Mayo Clinic
Target Recruit Count
6
Registration Number
NCT04857697
Locations
🇺🇸

Mayo Clinic in Florida, Jacksonville, Florida, United States

Anticaries Effect of Xylitol,Probiotic and Chlorhexidine Mouth Rinses Among Individuals at High Risk

Phase 2
Completed
Conditions
Mouthwashes
Cariostatic Agents
Interventions
First Posted Date
2020-05-22
Last Posted Date
2020-07-22
Lead Sponsor
Dr. Krupa NC
Target Recruit Count
60
Registration Number
NCT04399161
Locations
🇮🇳

JSS Dental College & Hospital, Mysore, Karnataka, India

the Microbiota Are Associated With Iodine-131 Therapy and Hypothyroidism

Early Phase 1
Conditions
Microbiota
Interventions
First Posted Date
2018-06-29
Last Posted Date
2018-07-16
Lead Sponsor
First Affiliated Hospital of Harbin Medical University
Target Recruit Count
30
Registration Number
NCT03574051
Locations
🇨🇳

First affiliated hospital of Harbin medical university, Harbin, Heilongjiang, China

Probiotics in PBC Patients of Poor Response to UDCA

Phase 2
Conditions
Primary Biliary Cholangitis (PBC)
Interventions
Dietary Supplement: Placebo
First Posted Date
2018-05-11
Last Posted Date
2020-01-07
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
60
Registration Number
NCT03521297
Locations
🇨🇳

Third Affliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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