Moxifloxacin

Generic Name
Moxifloxacin
Brand Names
Avelox, Moxeza, Vigamox
Drug Type
Small Molecule
Chemical Formula
C21H24FN3O4
CAS Number
151096-09-2
Unique Ingredient Identifier
U188XYD42P
Background

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

Indication

For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).

Associated Conditions
Acute Exacerbation of Chronic Bronchitis (AECB), Bacterial Conjunctivitis, Community Acquired Pneumonia (CAP), Plague, Postoperative Infections, Postoperative Inflammatory Response, Sinusitis, Skin Infections, Ocular bacterial infections
Associated Therapies
-

Albiglutide Thorough ECG Study in Healthy Volunteers

First Posted Date
2011-08-01
Last Posted Date
2017-06-08
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
94
Registration Number
NCT01406262

Development of an Optimal Antibiotic Regime for Long-term Therapy in Stable Chronic Obstructive Pulmonary Disease (COPD)

First Posted Date
2011-07-20
Last Posted Date
2012-06-01
Lead Sponsor
University College, London
Target Recruit Count
200
Registration Number
NCT01398072
Locations
🇬🇧

Academic Unit of Respiratory Medicine, Royal Free Hospital, London, United Kingdom

Effect of Methylnaltrexone (MNTX) on Electrocardiogram (ECG) Parameters and Cardiac Repolarization

First Posted Date
2011-06-01
Last Posted Date
2019-11-29
Lead Sponsor
Bausch Health Americas, Inc.
Target Recruit Count
546
Registration Number
NCT01363323
Locations
🇺🇸

Progenics Pharmaceuticals, Tarrytown, New York, United States

Determining Highest Dose Administration of TC-5214 and Evaluating Effect on the Electrical Activity in the Heart

First Posted Date
2011-05-25
Last Posted Date
2012-12-12
Lead Sponsor
AstraZeneca
Target Recruit Count
16
Registration Number
NCT01359618
Locations
🇬🇧

Research Site, London, United Kingdom

Pharmacokinetics and Safety of Moxifloxacin

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2011-04-05
Last Posted Date
2016-11-18
Lead Sponsor
University Medical Center Groningen
Target Recruit Count
9
Registration Number
NCT01329250
Locations
🇳🇱

University Medical Center Groningen, Groningen, Netherlands

Electrocardiographic (ECG) Safety Study of Droxidopa at Clinical and Supratherapeutic Dose

Phase 1
Completed
Conditions
Interventions
First Posted Date
2011-04-01
Last Posted Date
2012-03-07
Lead Sponsor
Chelsea Therapeutics
Target Recruit Count
52
Registration Number
NCT01327066
Locations
🇺🇸

PPD Phase I Clinic, Austin, Texas, United States

A Placebo-controlled Four Way Crossover Study to Asses the Effect of a Single Oral Dose of NKTR-118 on QTc Interval in Healthy Male Subjects

First Posted Date
2011-03-29
Last Posted Date
2014-10-15
Lead Sponsor
AstraZeneca
Target Recruit Count
45
Registration Number
NCT01325415
Locations
🇺🇸

Research Site, Overland Park, Kansas, United States

Treatment of Mycobacterium Xenopi Pulmonary Infection

First Posted Date
2011-02-17
Last Posted Date
2020-07-20
Lead Sponsor
Centre Hospitalier Universitaire, Amiens
Target Recruit Count
92
Registration Number
NCT01298336
Locations
🇫🇷

CH Béthune, Béthune, France

🇫🇷

CHU Besançon, Besançon, France

🇫🇷

CH Abbeville, Abbeville, France

and more 49 locations

A Safety Study to Assess the Effects of Therapeutic and Supratherapeutic Exenatide Concentrations on QT Interval in Healthy Subjects

First Posted Date
2011-02-16
Last Posted Date
2015-04-14
Lead Sponsor
AstraZeneca
Target Recruit Count
94
Registration Number
NCT01297062
Locations
🇺🇸

Research Site, Evansville, Indiana, United States

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