Dexamethasone

Generic Name
Dexamethasone
Brand Names
Baycadron, Ciprodex, Decadron, Dexamethasone Intensol, Dextenza, Dioptrol, Hexadrol, Hidex 6-day Taper, Maxidex, Maxitrol, Neofordex, Ozurdex, Taperdex 12 Day Taper, Taperdex 6 Day Taper, Taperdex 7-day Taper, Tobradex, Zcort 7 Day Taper
Drug Type
Small Molecule
Chemical Formula
C22H29FO5
CAS Number
50-02-2
Unique Ingredient Identifier
7S5I7G3JQL
Background

Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone.
...

Indication

Dexamethasone and ciprofloxacin otic suspension is indicated for bacterial infections with inflammation in acute otitis media and acute otitis externa. Intramuscular and intravenous injections are indicated for a number of endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, an...

Associated Conditions
Acute Gouty Arthritis, Acute Leukemia, Acute Otitis Externa, Acute Otitis Media (AOM), Adrenocortical Hyperfunction, Adrenocortical Insufficiency, Allergic Conjunctivitis (AC), Alopecia Areata (AA), Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Berylliosis, Bullous dermatitis herpetiformis, Bursitis, Chorioretinitis, Choroiditis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Conjunctivitis, Contact Dermatitis, Cushing's Syndrome, Dermatitis, Diabetic Macular Edema (DME), Discoid Lupus Erythematosus (DLE), Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Episcleritis, Erythroblastopenia, Eye Infections, Eye allergy, Glaucoma, Hypercalcemia, Immune Thrombocytopenia (ITP), Infection, Inflammation, Inflammation of the External Auditory Canal, Intraocular Inflammation, Iridocyclitis, Iritis, Keloids Scars, Keratitis, Lichen Planus (LP), Lichen simplex chronicus, Loeffler's syndrome, Lymphoma, Macular Edema, Meningitis caused by Mycobacterium Tuberculosis, Middle ear inflammation, Mucosal Inflammation of the eye, Multiple Myeloma (MM), Muscle Inflammation caused by Cataract Surgery of the eye, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Non-infectious Posterior Uveitis, Ocular Infections, Irritations and Inflammations, Ocular Inflammation, Ocular Inflammation and Pain, Ocular Irritation, Ocular Itching, Ophthalmia, Sympathetic, Optic Neuritis, Otitis Externa, Pemphigus, Perennial Allergic Rhinitis (PAR), Phlyctenular keratoconjunctivitis, Postoperative Infections of the eyes caused by susceptible bacteria, Posttraumatic Osteoarthritis, Regional Enteritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Rosacea, Sarcoidosis, Scleritis, Seasonal Allergic Rhinitis, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Tenosynovitis, Trichinosis, Tuberculosis (TB), Ulcerative Colitis, Uveitis, Vernal Keratoconjunctivitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Anterior eye segment inflammation, Corticosteroid-responsive dermatoses, Ear infection-not otherwise specified caused by susceptible bacteria, Exfoliative erythroderma, Granuloma annulare lesions, Non-suppurative Thyroiditis, Ocular bacterial infections, Severe Psoriasis, Steroid-responsive inflammation of the eye, Swelling of the eyes, Varicella-zoster virus acute retinal necrosis, Watery itchy eyes
Associated Therapies
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Bispecific T-cell Redirectors as Part of First Line Treatment in Transplant Eligible Multiple Myeloma Patients

First Posted Date
2024-07-17
Last Posted Date
2024-07-17
Lead Sponsor
North Estonia Medical Centre
Target Recruit Count
50
Registration Number
NCT06505369
Locations
🇳🇴

Oslo University Hospital, Oslo Myeloma Centre, Oslo, Norway

🇳🇴

Stavanger University Hospital, Stavanger, Norway

🇩🇰

Vejle hospital, Vejle, Denmark

and more 4 locations

A Comparative Study of Glucocorticoids Efficacy in Acute Respiratory Distress Syndrome

First Posted Date
2024-07-11
Last Posted Date
2024-12-16
Lead Sponsor
Fayoum University
Target Recruit Count
300
Registration Number
NCT06496997
Locations
🇪🇬

Fayoum University, Fayoum, Egypt

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty

First Posted Date
2024-06-24
Last Posted Date
2024-06-24
Lead Sponsor
Poznan University of Medical Sciences
Target Recruit Count
90
Registration Number
NCT06470100
Locations
🇵🇱

Poznan University of Medical Sciences, Poznan, Poznań, Poland

Liposomal Bupivacaine With Dexamethasone for Foot Surgery

First Posted Date
2024-06-20
Last Posted Date
2024-06-20
Lead Sponsor
Rothman Institute Orthopaedics
Target Recruit Count
126
Registration Number
NCT06465992
Locations
🇺🇸

Rothman Orthopaedic Institute, Philadelphia, Pennsylvania, United States

A Phase III Study of Eque-cel in Subjects With Len-refractory RRMM (FUMANBA-03)

First Posted Date
2024-06-18
Last Posted Date
2024-06-18
Lead Sponsor
Nanjing IASO Biotechnology Co., Ltd.
Target Recruit Count
240
Registration Number
NCT06464991
Locations
🇨🇳

Peking Union Medical College Hospital, Beijing, China

🇨🇳

Peking University Third Hospital, Beijing, China

🇨🇳

People's Hospital of Peking University, Beijing, China

and more 23 locations

Daratumumab/Daratumumab and Hyaluronidase-fihj in Combination With Pomalidomide and Dexamethasone for the Treatment of Patients With Newly Diagnosed AL Amyloidosis: a Prospective, Multicenter, Single-arm Study

First Posted Date
2024-06-12
Last Posted Date
2024-06-12
Lead Sponsor
Yongyong MA
Target Recruit Count
20
Registration Number
NCT06455748
Locations
🇨🇳

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma

First Posted Date
2024-05-30
Last Posted Date
2024-12-10
Lead Sponsor
Opna Bio LLC
Target Recruit Count
130
Registration Number
NCT06433947
Locations
🇺🇸

Emory Winchip Cancer Center, Atlanta, Georgia, United States

🇺🇸

Banner MD Anderson, Gilbert, Arizona, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

and more 3 locations

Dexamethasone Use in Pediatric Rhabdomyolysis Patients in Addition to Standard Protocols

Phase 1
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-05-28
Last Posted Date
2024-05-28
Lead Sponsor
Children's National Research Institute
Target Recruit Count
50
Registration Number
NCT06429982
Locations
🇺🇸

Childrens National, Washington, District of Columbia, United States

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