Alfentanil

Generic Name: Alfentanil

Brand Names: Alfenta

Drug Type: Small Molecule

Chemical Formula: C_₂₁H_₃₂N_₆O_₃

CAS Number: 71195-58-9

Unique Ingredient Identifier: 1N74HM2BS7

Background: A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.

Indication: For the management of postoperative pain and the maintenance of general anesthesia.

Associated Conditions: -

Associated Therapies: General Anesthesia, Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Perioperative analgesia

Clinical Trials

Evaluation of Propranolol's Effect on Pain and Inflammation.

Not Applicable

Completed

Conditions: Pain Measurement

Interventions: Drug: Placebo
Drug: Propranolol
Drug: Alfentanil

First Posted Date: 2010-03-29

Last Posted Date: 2017-02-24

Lead Sponsor: Martin Angst

Target Recruit Count: 10

Registration Number: NCT01094574

Locations: 🇺🇸
Stanford University School of Medicine, Stanford, California, United States

Diamorphine or Alfentanil for Subcutaneous Use in Hospice In-patients?

Not Applicable

Completed

Conditions: Cancer

Interventions: Drug: Alfentanil
Drug: Diamorphine

First Posted Date: 2010-01-14

Last Posted Date: 2015-03-17

Lead Sponsor: Gloucestershire Hospitals NHS Foundation Trust

Target Recruit Count: 18

Registration Number: NCT01049672

Locations: 🇬🇧
Sue Ryder Care Leckhampton Court Hospice, Cheltenham, Gloucestershire, United Kingdom

Alfentanil: Simultaneous Testing Pilot

Not Applicable

Completed

Conditions: Evaluate Two Paradigms for Simultaneous Assessment of Hepatic and Intestinal CYP3A

Interventions: Drug: Alfentanil

First Posted Date: 2009-11-05

Last Posted Date: 2019-05-17

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 6

Registration Number: NCT01008059

Locations: 🇺🇸
Washington University/Barnes Jewish Hospital, Saint Louis, Missouri, United States

Stress During Deep Sedation With Propofol With and Without Alfentanil

Phase 4

Completed

Conditions: Sedation

Interventions: Drug: propofol
Drug: alfentanil

First Posted Date: 2009-10-19

Last Posted Date: 2014-09-25

Lead Sponsor: Hennepin Healthcare Research Institute

Target Recruit Count: 20

Registration Number: NCT00997113

Locations: 🇺🇸
Hennepin County Medical Center, Minneapolis, Minnesota, United States

Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural Sedation

Phase 4

Completed

Conditions: Sedation

Interventions: Drug: Alfentanil
Drug: Propofol

First Posted Date: 2009-10-19

Last Posted Date: 2017-01-27

Lead Sponsor: Hennepin Healthcare Research Institute

Target Recruit Count: 126

Registration Number: NCT00997126

Locations: 🇺🇸
Hennepin County Medical Center, Minneapolis, Minnesota, United States

Study on the Development of Opioid Induced Hyperalgesia (OIH) After Exposure to Alfentanil

Not Applicable

Completed

Conditions: Hyperalgesia

Interventions: Drug: Alfentanil
Drug: Diphenhydramine

First Posted Date: 2009-10-08

Last Posted Date: 2017-10-06

Lead Sponsor: Johns Hopkins University

Target Recruit Count: 22

Registration Number: NCT00991809

Locations: 🇺🇸
Behavioral Pharmacology Research Unit, Baltimore, Maryland, United States

Heritability of Opioid Effects: A Twin Study

Not Applicable

Completed

Conditions: Pain

Interventions: Other: Saline placebo infusion
Drug: Alfentanil

First Posted Date: 2008-05-06

Last Posted Date: 2017-01-06

Lead Sponsor: Martin Angst

Target Recruit Count: 242

Registration Number: NCT00672438

Locations: 🇺🇸
Stanford University School of Medicine, Stanford, California, United States

Anesthesia in Flexible Bronchoscopy for Lung Cancer Diagnostic

Phase 4

Completed

Conditions: Lung Cancer

First Posted Date: 2007-02-27

Last Posted Date: 2007-02-27

Lead Sponsor: Hospital Pompeia

Registration Number: NCT00440960

Locations: 🇧🇷
Hospital Pompeia, Caxias do Sul, RS, Brazil
🇧🇷
Hospital Medianeira, Caxias do Sul, RS, Brazil
🇧🇷
General Hospital of Universidade de Caxias do Sul, Caxias do Sul, RS, Brazil

Neuronal Mechanisms of Sensory Processing During General Anesthesia

Not Applicable

Conditions: General Anesthesia

First Posted Date: 2007-02-13

Last Posted Date: 2010-07-30

Lead Sponsor: Ludwig-Maximilians - University of Munich

Target Recruit Count: 768

Registration Number: NCT00434382

Locations: 🇩🇪
Klinik fuer Anaesthesiologie am Universitätsklinikum Schleswig Holstein, Campus Luebeck, Lubeck, Germany
🇩🇪
Klinik fuer Anaesthesiologie der Ludwigs-Maximilians-Universitaet Muenchen, Munich, Germany
🇩🇪
Krankenhaus Friedrichshafen, Friedrichshafen, Germany

and more 1 locations

Genetic Determinants of Opioids Analgesia

Not Applicable

Completed

Conditions: Nephrolithiasis

First Posted Date: 2005-09-27

Last Posted Date: 2008-10-29

Lead Sponsor: Hadassah Medical Organization

Target Recruit Count: 100

Registration Number: NCT00226564

Locations: 🇮🇱
Hadassah Medical Organization, Jerusalem, Israel

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