Capsaicin
- Generic Name
- Capsaicin
- Brand Names
- Capzasin Quick Relief, Capzasin-HP, Castiva Warming, Dendracin Neurodendraxcin, Lidopro, Medi-derm, Medi-derm With Lidocaine, Medrox, Qutenza, Rematex, Xoten-C, Zostrix
- Drug Type
- Small Molecule
- Chemical Formula
- C18H27NO3
- CAS Number
- 404-86-4
- Unique Ingredient Identifier
- S07O44R1ZM
- Background
Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent capsaicin F...
- Indication
The capsaicin 8% patch is indicated in the treatment of neuropathic pain associated with post-herpetic neuralgia. There are multiple topical capsaicin formulations available, including creams and solutions, indicated for temporary analgesia in muscle and join pain as well as neuropathic pain.
- Associated Conditions
- Back Pain Lower Back, Back pain, Bursitis, Contusions, Inflammatory Reaction caused by Rheumatism, Muscle Cramps, Musculoskeletal Pain, Neuropathic Pain, Osteoarthritis (OA), Pain caused by Rheumatism, Periarthritis, Soft Tissue Injury, Tendinitis, Acute nonspecific tenosynovitis, Articular inflammation
- Associated Therapies
- -
Functional Magnetic Resonance Imaging of ATP Cough in Chronic Cough Patients
- Conditions
- Interventions
- First Posted Date
- 2018-10-29
- Last Posted Date
- 2024-08-22
- Lead Sponsor
- Stuart Mazzone
- Target Recruit Count
- 58
- Registration Number
- NCT03722849
- Locations
- 🇦🇺
The University of Melbourne, Parkville, Victoria, Australia
The Effect of Injection Site Cooling on Pain Experienced After the Administration of CNTX-4975-05 Into the Knee
- Conditions
- Interventions
- First Posted Date
- 2018-03-21
- Last Posted Date
- 2018-12-19
- Lead Sponsor
- Centrexion Therapeutics
- Target Recruit Count
- 20
- Registration Number
- NCT03472677
- Locations
- 🇬🇧
MAC Clinical Research, Manchester, United Kingdom
Airway Protective Mechanisms in PD (R01)
- First Posted Date
- 2017-10-25
- Last Posted Date
- 2024-10-10
- Lead Sponsor
- University of Florida
- Target Recruit Count
- 119
- Registration Number
- NCT03321019
- Locations
- 🇺🇸
University of Florida Center for Movement Disorders and Neurorestoration, Gainesville, Florida, United States
Desensitization of Nociceptive Afferents by Application of Topical Capsaicin, Trans-cinnamaldehyde and L-menthol
- Conditions
- Interventions
- First Posted Date
- 2017-04-27
- Last Posted Date
- 2017-04-27
- Lead Sponsor
- Aalborg University
- Target Recruit Count
- 22
- Registration Number
- NCT03132142
- Locations
- 🇩🇰
SMI, Aalborg, Denmark
Normal Breathing and Swallowing in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2017-04-20
- Last Posted Date
- 2021-01-14
- Lead Sponsor
- University of Florida
- Target Recruit Count
- 49
- Registration Number
- NCT03122145
- Locations
- 🇺🇸
University of Florida, Gainesville, Florida, United States
Effect of Muscular Exercise on Cough Reflex
- Conditions
- Interventions
- First Posted Date
- 2016-08-30
- Last Posted Date
- 2016-08-30
- Lead Sponsor
- Central Hospital, Nancy, France
- Target Recruit Count
- 60
- Registration Number
- NCT02882555
Capsaicin Effect on Cytokines Profile in Dyslipidemia
- Conditions
- Interventions
- First Posted Date
- 2016-07-06
- Last Posted Date
- 2016-07-19
- Lead Sponsor
- University of Guadalajara
- Target Recruit Count
- 17
- Registration Number
- NCT02823912
Biomarker Study in Participants With Migraine
- First Posted Date
- 2016-05-09
- Last Posted Date
- 2019-04-09
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 37
- Registration Number
- NCT02766517
- Locations
- 🇺🇸
Arizona Research Center, Phoenix, Arizona, United States
🇺🇸Pharmacology Research Institute, Newport Beach, Newport Beach, California, United States
🇺🇸Parexel Early Phase Unit at Glendale, Glendale, California, United States
Respiratory Strength Training in Persons With Amyotrophic Lateral Sclerosis (ALS)
- Conditions
- Interventions
- First Posted Date
- 2016-03-16
- Last Posted Date
- 2020-01-27
- Lead Sponsor
- University of Florida
- Target Recruit Count
- 50
- Registration Number
- NCT02710110
- Locations
- 🇺🇸
UF Health Shands, Gainesville, Florida, United States
Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)
- Conditions
- Interventions
- Device: Micro Mouth Pressure MeterDevice: Iowa Oral Performance InstrumentDevice: Electrical Impedance MyographyDrug: CapsaicinProcedure: Videofluoroscopic Swallowing StudyProcedure: Pulmonary Function TestingOther: Swallowing Related Quality of Life QuestionnaireOther: Functional Oral Intake ScaleOther: Amyotrophic Lateral Sclerosis Functional Rating Scale-RevisedOther: Eating Assessment Tool-10Other: Communicative Effectiveness SurveyOther: The Center for Neurologic Studies Bulbar Function Scale
- First Posted Date
- 2016-03-16
- Last Posted Date
- 2017-12-21
- Lead Sponsor
- University of Florida
- Target Recruit Count
- 21
- Registration Number
- NCT02710162
- Locations
- 🇺🇸
University of Florida, Gainesville, Florida, United States
Drug Development Updates
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