MedPath

Petrolatum

Generic Name
Petrolatum
Brand Names
A+d Diaper Rash, Anbesol Cold Sore Therapy, Calazime Skin Protectant, Calmoseptine Ointment, DermaCerin, Flanders, Lubrifresh P.M., Periguard, Preparation H Cream, Preparation H Reformulated Jun 2013, Refresh Lacri-lube, Refresh PM, Resinol, Soothe & Cool Skin Paste, Soothe Night Time, Stye, Systane, Systane Nighttime, Tears Again Ointment, Vusion, Zincofax
Drug Type
Small Molecule
CAS Number
8009-03-8
Unique Ingredient Identifier
B6E5W8RQJ4
Background

A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.

Indication

For use as an over the counter skin protectant . Commonly used to treat diaper rash and chapped lips .

Associated Conditions
Dermabrasion, Diaper Rash, Dry Skin, Itching of the perianal area, Pain, Skin Irritation, Burning skin sensation, Minor burns
Associated Therapies
Skin protectant

A Study to Document the Effect of Petrolatum on Innate Immune Responses in the Skin

Not Applicable
Completed
Conditions
Skin Disease
Interventions
First Posted Date
2015-01-14
Last Posted Date
2017-05-16
Lead Sponsor
Rockefeller University
Target Recruit Count
20
Registration Number
NCT02338076
Locations
🇺🇸

The Rockefeller University, New York, New York, United States

A Trial Comparing the Efficacy and Safety of Open Dressing With Petrolatum Jelly vs. Standard Gauze Dressing With Silver Sulfadiazine

Phase 3
Completed
Conditions
Superficial Partial Thickness Burns
Interventions
First Posted Date
2014-04-10
Last Posted Date
2014-04-10
Lead Sponsor
University of the Philippines
Target Recruit Count
50
Registration Number
NCT02109718
Locations
🇵🇭

Philippine General Hospital - University of the Philippines Manila, Manila, National Capital Region, Philippines

Combined Cumulative Irritation Potential and Repeat Insult Patch Test of LEO 90100

Phase 1
Completed
Conditions
Psoriasis Vulgaris
Interventions
First Posted Date
2013-09-05
Last Posted Date
2025-02-24
Lead Sponsor
LEO Pharma
Target Recruit Count
224
Registration Number
NCT01935869
Locations
🇫🇷

CPCAD, Centre de Pharmacologie Clinique Appliquée à la Dermatologie, Hôpital de l'Archet 2, Nice Cedex 3, France

A Study to Evaluate Skin Irritation and Photo Irritation of JNJ 10229570-AAA on Intact Skin of Japanese Healthy Male Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: JNJ 10229570-AAA 1.2% cream
Drug: JNJ 10229570-AAA 2.4% cream
Drug: JNJ 10229570-AAA 3.6% cream
Drug: Color-matched vehicle in a cream formulation containing 0 mg of JNJ 10229570-AAA
First Posted Date
2011-12-19
Last Posted Date
2012-10-31
Lead Sponsor
Janssen Pharmaceutical K.K.
Target Recruit Count
30
Registration Number
NCT01494714

Clinical Trial of 0.0003% Calcitriol, 0.1% Tacrolimus, and Petrolatum for the Treatment of Pityriasis Alba

Phase 4
Completed
Conditions
Pityriasis Alba
Interventions
First Posted Date
2011-07-06
Last Posted Date
2012-09-26
Lead Sponsor
Universidad Autonoma de San Luis Potosí
Target Recruit Count
39
Registration Number
NCT01388517
Locations
🇲🇽

Dermatology Department. Hospital Central "Dr. Ignacio Morones Prieto", San Luis Potosi, Mexico

Effects of Topical Vitamin K, Vitamin K and Retinol, and Arnica on Post-Laser Bruising

First Posted Date
2006-08-15
Last Posted Date
2021-12-03
Lead Sponsor
Northwestern University
Target Recruit Count
16
Registration Number
NCT00363038
Locations
🇺🇸

Northwestern University Feinberg School of Medicine, Department of Dermatology, Chicago, Illinois, United States

The Impact of Treating Staphylococcus Aureus Infection and Colonization on the Clinical Severity of Atopic Dermatitis

First Posted Date
2005-09-16
Last Posted Date
2014-12-08
Lead Sponsor
Northwestern University
Target Recruit Count
31
Registration Number
NCT00179959
Locations
🇺🇸

Childrens Memorial Hospital, Chicago, Illinois, United States

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