Mupirocin

Generic Name
Mupirocin
Brand Names
Bactroban, Centany, Pirnuo
Drug Type
Small Molecule
Chemical Formula
C26H44O9
CAS Number
12650-69-0
Unique Ingredient Identifier
D0GX863OA5
Background

Mupirocin, formerly termed pseudomonic acid A, is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism Pseudomonas fluorescens, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and...

Indication

Indicated for the treatment of impetigo and secondary skin infections, leading to traumatic skin lesions, due to Staphylococcus aureus and Streptococcus pyogenes.

Associated Conditions
Impetigo, Impetigo caused by Staphylococcus aureus, Impetigo caused by streptococcus pyogenes, Secondary infection Skin infection, Staphylococcus aurea colonization of the nasal passage
Associated Therapies
-

Bacterial Decolonization Within Dyads

Not Applicable
Recruiting
Conditions
Interventions
First Posted Date
2024-08-07
Last Posted Date
2024-12-19
Lead Sponsor
Duke University
Target Recruit Count
20
Registration Number
NCT06541145
Locations
🇺🇸

Duke University, Durham, North Carolina, United States

Effects of Topical Gentamicin on the Prevention of Peritoneal Dialysis Related Infection

First Posted Date
2022-02-22
Last Posted Date
2022-02-22
Lead Sponsor
Phramongkutklao College of Medicine and Hospital
Target Recruit Count
60
Registration Number
NCT05251584
Locations
🇹🇭

Phramongkutklao Hospital, Ratchathewi, Bangkok, Thailand

Topical Antibiotics in Chronic Rhinosinusitis

First Posted Date
2018-09-17
Last Posted Date
2022-04-20
Lead Sponsor
Mayo Clinic
Target Recruit Count
19
Registration Number
NCT03673956
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

STaph Aureus Resistance-Treat Early and Repeat (STAR-TER)

First Posted Date
2018-04-05
Last Posted Date
2024-04-09
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
42
Registration Number
NCT03489629
Locations
🇺🇸

University of Texas Southwestern Medical Center, Dallas, Texas, United States

🇺🇸

Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States

🇺🇸

University of Washington Medical Center and Seattle Children's, Seattle, Washington, United States

and more 6 locations

S. Aureus Decolonization in HPN Patients.

First Posted Date
2017-06-01
Last Posted Date
2022-05-31
Lead Sponsor
Radboud University Medical Center
Target Recruit Count
63
Registration Number
NCT03173053
Locations
🇩🇰

Rigshospitalet, Copenhagen, Denmark

🇩🇰

Aalborg Universitetshospital, Aalborg, Denmark

🇳🇱

Radboud UMC, Nijmegen, Gelderland, Netherlands

and more 1 locations

Treatment of Nasal Staphylococcus Aureus Colonization in Patients With HHT

First Posted Date
2016-11-15
Last Posted Date
2016-11-15
Lead Sponsor
Hospital Italiano de Buenos Aires
Target Recruit Count
40
Registration Number
NCT02963129
Locations
🇦🇷

Hospital Italiano de Buenos Aires, Gascon 450, Buenos Aires, Argentina

🇦🇷

Hospital Italiano de Buenos Aires, Peron 4190, Ciudad Autonoma de Buenos Aires, Capital Federal, Argentina

Staph Household Intervention for Eradication (SHINE)

First Posted Date
2015-10-09
Last Posted Date
2024-05-23
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
835
Registration Number
NCT02572791
Locations
🇺🇸

St. Louis Children's Hospital, Saint Louis, Missouri, United States

🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

Study to Assess Eradication of Nasal Carriage of Staphylococcus Aureus (SA) With Mupirocin (Bactroban 2% Nasal Ointment)

Phase 4
Completed
Conditions
Interventions
First Posted Date
2014-11-06
Last Posted Date
2016-03-01
Lead Sponsor
Destiny Pharma Plc
Target Recruit Count
12
Registration Number
NCT02284555
Locations
🇬🇧

Simbec Reseach Ltd, Wales, United Kingdom

The Use of Antibiotic Sinonasal Rinse After Sinus Surgery

Phase 4
Completed
Conditions
Interventions
First Posted Date
2014-08-18
Last Posted Date
2017-06-26
Lead Sponsor
University of Miami
Target Recruit Count
68
Registration Number
NCT02218307
Locations
🇺🇸

University of Miami Miller School of Medicine, ENT Dept, Miami, Florida, United States

Checklist to Prevent MRSA Surgical Site Infections

First Posted Date
2014-08-13
Last Posted Date
2021-03-11
Lead Sponsor
VA Office of Research and Development
Target Recruit Count
1794
Registration Number
NCT02216227
Locations
🇺🇸

Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore, Maryland, United States

🇺🇸

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts, United States

🇺🇸

VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan, United States

and more 8 locations
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