DeepMed Research

Columbia University

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1754-01-01

Employees: 20.8K

Market Cap: -

Website: https://www.arch.columbia.edu

Clinical Trials

FUS Etoposide for DMG

Phase 1

Recruiting

Conditions: Diffuse Intrinsic Pontine Glioma
Diffuse Midline Glioma, H3 K27M-Mutant

Interventions: Drug: Etoposide; Oral, 50 Mg
Device: Focused ultrasound with neuro-navigator-controlled sonication

First Posted Date: 2023-03-09

Last Posted Date: 2025-05-04

Lead Sponsor: Columbia University

Target Recruit Count: 10

Registration Number: NCT05762419

Locations: 🇺🇸
Columbia University Irving Medical Center, New York, New York, United States

Young Adults With Violent Behavior During Early Psychosis

Not Applicable

Recruiting

Conditions: Schizophrenia
Schizo Affective Disorder
Delusional Disorder
Other Specified Schizophrenia Spectrum and Other Psychotic Disorder
Schizophreniform Disorders

First Posted Date: 2023-03-06

Last Posted Date: 2024-08-28

Lead Sponsor: Columbia University

Target Recruit Count: 16

Registration Number: NCT05756855

Motivation Skills Training for Schizophrenia

Not Applicable

Completed

Conditions: Schizophrenia
Schizoaffective Disorder

Interventions: Behavioral: Motivation Skills Training (MST)

First Posted Date: 2023-02-27

Last Posted Date: 2024-12-18

Lead Sponsor: Columbia University

Target Recruit Count: 8

Registration Number: NCT05746455

Locations: 🇺🇸
The Bridge Inc, New York, New York, United States

Impact of Cuddle and Calm Booklets on Parent-Child Emotional Connection a Nurture-based Children's Book

Not Applicable

Withdrawn

Conditions: Emotional Problem

Interventions: Behavioral: Poem book about physical health and safety
Behavioral: Poem book about relational health

First Posted Date: 2023-02-22

Last Posted Date: 2023-02-22

Lead Sponsor: Columbia University

Registration Number: NCT05739760

Effect of Alpelisib in Healthy Volunteers

Phase 1

Completed

Conditions: Hyperinsulinemia
Insulin Resistance
Dyslipidemias

Interventions: Device: FreeStyle Libre Pro
Drug: Placebo (microcrystalline cellulose), 2 capsules
Diagnostic Test: Oral glucose tolerance test (OGTT) with Trutol glucose beverage
Dietary Supplement: BOOST Plus nutritional beverage

First Posted Date: 2023-02-17

Last Posted Date: 2023-12-21

Lead Sponsor: Columbia University

Target Recruit Count: 23

Registration Number: NCT05733455

Locations: 🇺🇸
Columbia University Irving Medical Center, New York, New York, United States

Glycemic Effect of Diazoxide in NAFLD

Phase 1

Recruiting

Conditions: Non-Alcoholic Fatty Liver Disease
Hyperinsulinemia
Insulin Resistance
Prediabetic State

Interventions: Drug: Diazoxide oral suspension, 1 mg per kg per dose
Drug: Diazoxide oral suspension, 2 mg per kg per dose
Drug: Placebo
Device: FreeStyle Libre Pro
Drug: Deuterated water (2H2O/D2O)

First Posted Date: 2023-02-15

Last Posted Date: 2025-01-08

Lead Sponsor: Columbia University

Target Recruit Count: 72

Registration Number: NCT05729282

Locations: 🇺🇸
Columbia University Irving Medical Center, New York, New York, United States

PROtecting Maternal Brains From Injury and Stroke

Not Applicable

Completed

Conditions: Maternal Hypertension
Preeclampsia

Interventions: Device: NIRS based personalized blood pressure management

First Posted Date: 2023-02-13

Last Posted Date: 2025-03-11

Lead Sponsor: Columbia University

Target Recruit Count: 26

Registration Number: NCT05726279

Locations: 🇺🇸
Columbia University Irving Medical Center / NewYork-Presbyterian Hospital (NYP), New York, New York, United States

Pancreatic Clamp in NAFLD

Phase 1

Suspended

Conditions: Obesity
Prediabetic State
Insulin Resistance
Hyperinsulinemia
Non-Alcoholic Fatty Liver Disease

Interventions: Drug: Insulin human
Drug: Octreotide Acetate
Drug: Glucagon
Drug: Growth Hormone, Human
Other: [6,6-2H2] D-glucose
Drug: 20% D-glucose (aq)
Dietary Supplement: BOOST Plus
Dietary Supplement: CORE Bar
Device: Harvard Apparatus PHD ULTRA CP syringe pump
Device: Yellow Springs Instruments (YSI) 2500 Biochemistry Glucose/Lactate Analyzer

First Posted Date: 2023-02-13

Last Posted Date: 2025-04-03

Lead Sponsor: Columbia University

Target Recruit Count: 42

Registration Number: NCT05724134

Locations: 🇺🇸
Columbia University Irving Medical Center, New York, New York, United States

Sleep in SNOO Smart Sleeper Bassinet in Preterm Infants

Not Applicable

Active, not recruiting

Conditions: Very Preterm Maturity of Infant
Prematurity

Interventions: Device: SNOO Smart Sleeper
Device: Traditional bassinet

First Posted Date: 2023-02-03

Last Posted Date: 2025-04-08

Lead Sponsor: Columbia University

Target Recruit Count: 50

Registration Number: NCT05711927

Locations: 🇺🇸
Morgan Stanley Children's Hospital Neonatal Intensive Care Unit, NewYork Presbyterian, New York, New York, United States

COVID-19 Self-testing Study

Not Applicable

Completed

Conditions: COVID-19

Interventions: Behavioral: SMARTest mobile app for COVID-19 self-testing

First Posted Date: 2023-01-27

Last Posted Date: 2024-02-16

Lead Sponsor: Columbia University

Target Recruit Count: 100

Registration Number: NCT05701878

Locations: 🇺🇸
ICAP Harlem Prevention Center, New York, New York, United States

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