Regeneron Pharmaceuticals

Regeneron Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Established
1988-01-01
Employees
13.4K
Market Cap
$132.4B
Website
http://www.regeneron.com
Introduction

Regeneron Pharmaceuticals, Inc. is a biotechnology company, which engages in the discovery, invention, development, manufacture, and commercialization of medicines. Its product portfolio includes the following brands: Dupixent, Evkeeza, Eylea, Inmazeb, and Kevzara. The firm accelerates the traditional drug development process through its proprietary VelociSuite technologies such as VelocImmune, which uses unique genetically humanized mice to produce optimized fully human antibodies and bispecific antibodies. The company was founded by Alferd G. Gilman, Leonard S. Schleifer, George Damis Yancopoulos, and Eric M. Shooter on January 8, 1988, and is headquartered in Tarrytown, NY.

Study of Evinacumab (REGN1500) in Caucasian and in Japanese Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2017-05-10
Last Posted Date
2018-06-25
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
96
Registration Number
NCT03146416
Locations
🇺🇸

WCCT Global, Inc., Cypress, California, United States

PD-1 in Patients With Advanced Basal Cell Carcinoma Who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or Were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy

Phase 2
Completed
Conditions
Interventions
First Posted Date
2017-04-28
Last Posted Date
2024-05-20
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
138
Registration Number
NCT03132636
Locations
🇺🇸

Mount Sinai Hospital, New York, New York, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

🇺🇸

Overlook Medical Center, Summit, New Jersey, United States

and more 68 locations

Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of REGN3918 in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2017-04-14
Last Posted Date
2018-09-26
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
56
Registration Number
NCT03115996
Locations
🇬🇧

Covance Clinical Research Unit (CRU) Ltd., Leeds, United Kingdom

Study of REGN3500 and Dupilumab in Patients With Asthma

First Posted Date
2017-04-13
Last Posted Date
2020-01-18
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
32
Registration Number
NCT03112577
Locations
🇺🇸

WCCT Global, Cypress, California, United States

🇬🇧

Celerion, Belfast, United Kingdom

🇬🇧

Hammersmith Medicine Research, London, United Kingdom

and more 2 locations

Study of REGN 2810 Compared to Platinum-Based Chemotherapies in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC)

First Posted Date
2017-03-23
Last Posted Date
2024-06-18
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
712
Registration Number
NCT03088540
Locations
🇺🇦

Clinical Study Site 2, Kyiv, Ukraine

🇹🇷

Clinical Study Site 3, İzmir, Turkey

🇧🇷

Clinical Study Site #3, São Paulo, Brazil

and more 9 locations

Phase 1B Study Evaluating Alternative Routes of Administration of CMP-001 in Combination With Pembrolizumab in Participants With Advanced Melanoma

Phase 1
Completed
Conditions
Interventions
First Posted Date
2017-03-21
Last Posted Date
2022-08-03
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
30
Registration Number
NCT03084640
Locations
🇺🇸

University of Colorado, Aurora, Colorado, United States

🇺🇸

University of California, Los Angeles, Los Angeles, California, United States

🇺🇸

University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States

and more 1 locations

Efficacy and Safety of Dupilumab in Participants ≥12 to <18 Years of Age, With Moderate-to-severe Atopic Dermatitis

First Posted Date
2017-02-15
Last Posted Date
2019-07-23
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
251
Registration Number
NCT03054428
Locations
🇨🇦

Regeneron Investigational Site, Windsor, Ontario, Canada

🇨🇦

Regeneron Research Site, Richmond Hill, Ontario, Canada

Study of Dupilumab Auto-injector Device When Used by Patients With Atopic Dermatitis

First Posted Date
2017-02-10
Last Posted Date
2018-08-01
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
176
Registration Number
NCT03050151
Locations
🇺🇸

Regeneron Investigational Site, Tacoma, Washington, United States

Study of REGN3767 (Anti-LAG-3) With or Without REGN2810 (Anti-PD1) in Advanced Cancers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-12-29
Last Posted Date
2024-05-01
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
333
Registration Number
NCT03005782
Locations
🇺🇸

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

🇺🇸

California Pacific Medical Center (CPMC), San Francisco, California, United States

🇺🇸

Sarah Cannon Research Institute, Nashville, Tennessee, United States

and more 40 locations

An Exploratory Tumor Biopsy-driven Study to Understand the Relationship Between Biomarkers and Clinical Response in Melanoma Patients Receiving REGN2810 (Anti-PD-1)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-12-23
Last Posted Date
2020-04-20
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
47
Registration Number
NCT03002376
Locations
🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

🇰🇷

Asan Medical Center, Seoul, Korea, Republic of

🇰🇷

Samsung Medical Center, Seoul, Korea, Republic of

and more 5 locations
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