UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1943-01-01

Employees: 8.1K

Market Cap: -

Website: http://www.utsouthwestern.edu

Clinical Trials

Mindfulness and Yoga Therapy for Acute Pain in Sickle Cell Disease

Not Applicable

Completed

Conditions: Sickle Cell Disease
Sickle Cell Crisis

Interventions: Behavioral: Mindfulness meditation, breathing exercises (including incentive spirometry), and yoga therapy

First Posted Date: 2022-10-07

Last Posted Date: 2023-02-13

Lead Sponsor: University of Texas Southwestern Medical Center

Target Recruit Count: 39

Registration Number: NCT05572294

Locations: 🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States

Cognitive Outcomes of Brain Stimulation As a Later-in-Life Treatment

Not Applicable

Recruiting

Conditions: Dementia
Mild Cognitive Impairment
Amnestic Mild Cognitive Impairment - aMCI

Interventions: Device: NeuroElectric StarStim
Device: Sham Treatment

First Posted Date: 2022-10-03

Last Posted Date: 2024-08-12

Lead Sponsor: University of Texas Southwestern Medical Center

Target Recruit Count: 9999

Registration Number: NCT05564715

Locations: 🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States

LOcoregional Vs Systemic Therapy in Patients with BCLC Stage B HCC

Phase 2

Recruiting

Conditions: Hepatocellular Carcinoma

Interventions: Drug: Atezolizumab and bevacizumab
Radiation: transarterial chemoembolization (TACE) or transarterial radioembolization (TARE

First Posted Date: 2022-09-13

Last Posted Date: 2024-10-03

Lead Sponsor: University of Texas Southwestern Medical Center

Target Recruit Count: 204

Registration Number: NCT05537402

Locations: 🇺🇸
Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas, Texas, United States

Furoscix in Heart Failure Patients With Diuretic Resistance

Phase 2

Completed

Conditions: Heart Failure

Interventions: Combination Product: Furoscix
Drug: Diuretic Therapy

First Posted Date: 2022-09-06

Last Posted Date: 2024-12-17

Lead Sponsor: University of Texas Southwestern Medical Center

Target Recruit Count: 70

Registration Number: NCT05528588

Locations: 🇺🇸
UT Southwestern Medical Center, Dallas, Texas, United States

Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)

Phase 1

Recruiting

Conditions: Spasticity, Muscle
Microcephaly
Spastic Paraplegia
Intellectual Deficiency
Growth Retardation
SPG50

Interventions: Biological: MELPIDA

First Posted Date: 2022-08-26

Last Posted Date: 2024-10-08

Lead Sponsor: Elpida Therapeutics SPC

Target Recruit Count: 4

Registration Number: NCT05518188

Locations: 🇺🇸
Children's Medical Center Dallas, Dallas, Texas, United States

Polypill in Acute Coronary Syndrome

Phase 2

Recruiting

Conditions: Lipid Disorder
Coronary Artery Disease
Acute Coronary Syndrome

Interventions: Drug: Polypill
Drug: Usual Care (individual medications prescribed by primary cardiologist)

First Posted Date: 2022-08-25

Last Posted Date: 2024-12-17

Lead Sponsor: University of Texas Southwestern Medical Center

Target Recruit Count: 120

Registration Number: NCT05514938

Locations: 🇺🇸
UT Southwestern Medical Center, Dallas, Texas, United States

Fractionated 1927nm Laser for Hyperpigmentation in Fitzpatrick Skin Phototypes V and VI

Not Applicable

Active, not recruiting

Conditions: Hyperpigmentation

Interventions: Device: MOXI

First Posted Date: 2022-08-09

Last Posted Date: 2024-10-10

Lead Sponsor: University of Texas Southwestern Medical Center

Target Recruit Count: 20

Registration Number: NCT05493280

Locations: 🇺🇸
UT Southwestern Medical Center- Dept of Plastic Surgery, Dallas, Texas, United States

Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart Transplantation

Phase 4

Recruiting

Conditions: Transthyretin Cardiac Amyloidosis

Interventions: Drug: Tafamidis 61 MG

First Posted Date: 2022-08-05

Last Posted Date: 2024-11-22

Lead Sponsor: University of Texas Southwestern Medical Center

Target Recruit Count: 25

Registration Number: NCT05489523

Locations: 🇺🇸
Cedars-Sinai, Beverly Hills, California, United States
🇺🇸
Columbia University Medical Center, New York, New York, United States
🇺🇸
UT Southwestern Medical Center, Dallas, Texas, United States

Radiofrequency Ablation and Steroid Versus Steroid Alone for Relief of Pain in Patients With Advanced Knee and Hip Osteoarthritis

Not Applicable

Recruiting

Conditions: Osteoarthritis, Knee
Osteoarthritis, Hip

Interventions: Procedure: Radiofrequency Ablation (RFA)
Procedure: Perineural Steroid Injection

First Posted Date: 2022-08-05

Last Posted Date: 2024-01-09

Lead Sponsor: University of Texas Southwestern Medical Center

Target Recruit Count: 80

Registration Number: NCT05490355

Locations: 🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Recruiting

Conditions: Amyloidosis, Hereditary
Amyloidosis, Familial
Transthyretin Gene Mutation
Amyloidosis Cardiac
Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy

First Posted Date: 2022-08-05

Last Posted Date: 2024-05-30

Lead Sponsor: University of Texas Southwestern Medical Center

Target Recruit Count: 500

Registration Number: NCT05489549

Locations: 🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States
🇺🇸
Columbia University Medical Center, New York, New York, United States
🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States

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