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NATIONWIDE CHILDREN'S HOSPITAL

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1892-01-01

Employees: 10K

Market Cap: -

Website: http://www.nationwidechildrens.org

Clinical Trials

Spanish BMT4me Usability & Acceptability

Recruiting

Conditions: Bone Marrow Transplant

Interventions: Other: BMT4me

First Posted Date: 2024-04-11

Last Posted Date: 2025-02-12

Lead Sponsor: Nationwide Children's Hospital

Target Recruit Count: 30

Registration Number: NCT06361173

Locations: 🇺🇸
Columbia University Irving Medical Center, New York, New York, United States
🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

Early Phase 1

Not yet recruiting

Conditions: Glioblastoma Multiforme
WHO Grade IV Glioma
Diffuse Midline Glioma, H3K27-altered
High Grade Glioma
Diffuse Intrinsic Pontine Glioma
Infant Type Hemispheric Glioma
Anaplastic Astrocytoma
Glioblastoma
WHO Grade III Glioma

Interventions: Drug: Lorlatinib
Drug: Lorlatinib with chemotherapy1
Drug: Lorlatinib with chemotherapy 2
Drug: Lorlatinib post Radiation

First Posted Date: 2024-03-27

Last Posted Date: 2025-06-04

Lead Sponsor: Nationwide Children's Hospital

Target Recruit Count: 15

Registration Number: NCT06333899

Locations: 🇺🇸
Children's Hospital Colorado, Aurora, Colorado, United States
🇺🇸
Children's National Medical Center, Washington, District of Columbia, United States
🇺🇸
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States

and more 14 locations

VR-PAT and FNIRS to Identify CNS Biomarkers of Pain

Not Applicable

Not yet recruiting

Conditions: Acute Pain
Burns
Pediatric ALL
Procedural Pain

Interventions: Other: VR-PAT

First Posted Date: 2024-03-12

Last Posted Date: 2025-02-12

Lead Sponsor: Nationwide Children's Hospital

Target Recruit Count: 4

Registration Number: NCT06303687

Locations: 🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States

Regional Anesthesia EMG Study

Not Applicable

Recruiting

Conditions: Surgery

Interventions: Device: BlockSynop surface electromyography device
Drug: Sevoflurane
Drug: Clonidine

First Posted Date: 2024-02-29

Last Posted Date: 2025-05-14

Lead Sponsor: Nationwide Children's Hospital

Target Recruit Count: 124

Registration Number: NCT06287151

Locations: 🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States

Applying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness

Not Applicable

Recruiting

Conditions: Sickle Cell Disease

Interventions: Behavioral: Video Directly Observed Therapy (VDOT)
Behavioral: Health Reminder Tip Alerts

First Posted Date: 2024-02-20

Last Posted Date: 2025-04-08

Lead Sponsor: Nationwide Children's Hospital

Target Recruit Count: 60

Registration Number: NCT06264700

Locations: 🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States
🇺🇸
Lurie Children's Hospital, Chicago, Illinois, United States
🇺🇸
Hasbro Children's Hospital, Providence, Rhode Island, United States

Improving Status Epilepticus Treatment Times

Not Applicable

Recruiting

Conditions: Status Epilepticus

Interventions: Other: Quality improvement bundle and local PDSA cycles without central support
Other: Quality improvement bundle
Other: Quality improvement bundle and local PDSA cycles with central support

First Posted Date: 2024-01-08

Last Posted Date: 2024-09-30

Lead Sponsor: Nationwide Children's Hospital

Target Recruit Count: 450

Registration Number: NCT06194747

Locations: 🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States

GERD Infant Feeding Therapeutics Trial (GIFT Trial)

Not Applicable

Recruiting

Conditions: GERD in Infants

Interventions: Drug: Omeprazole
Other: AR formula

First Posted Date: 2023-11-02

Last Posted Date: 2024-10-04

Lead Sponsor: Nationwide Children's Hospital

Target Recruit Count: 369

Registration Number: NCT06114836

Locations: 🇺🇸
Nationwide Children's Hospita, Columbus, Ohio, United States

FSHD Molecular Characterization

Recruiting

Conditions: Facio-Scapulo-Humeral Dystrophy

First Posted Date: 2023-10-23

Last Posted Date: 2023-10-23

Lead Sponsor: Nationwide Children's Hospital

Target Recruit Count: 25

Registration Number: NCT06096441

Locations: 🇺🇸
The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States

αβT Cell/CD19+ B Cell Depletion for Alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT)

Not Applicable

Recruiting

Conditions: Hematopoietic Stem Cell Transplantation
Hematologic Malignancy

Interventions: Device: CliniMACS®

First Posted Date: 2023-10-13

Last Posted Date: 2025-04-02

Lead Sponsor: Nationwide Children's Hospital

Target Recruit Count: 50

Registration Number: NCT06082947

Locations: 🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States

Predictors of Inhaled Nitric Oxide Responsiveness in Patients With PPHN

Withdrawn

Conditions: Hypoxic Respiratory Failure
PPHN

First Posted Date: 2023-09-21

Last Posted Date: 2023-09-21

Lead Sponsor: Nationwide Children's Hospital

Registration Number: NCT06043635

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