Vaginal Microbiome Seeding and Health Outcomes in Cesarean-delivered Neonates.
- Conditions
- Cesarean Delivery Affecting NewbornIntestinal MicrobiomeGastrointestinal MicrobiomeHost Microbial InteractionsObesity, ChildhoodMicrobiota
- Interventions
- Other: No Vaginal SeedingBiological: Vaginal Seeding
- First Posted Date
- 2017-10-02
- Last Posted Date
- 2024-06-18
- Target Recruit Count
- 600
- Registration Number
- NCT03298334
- Locations
- 🇺🇸
Inova Health System, Falls Church, Virginia, United States
A Trial of Mepolizumab Adjunctive Therapy for the Prevention of Asthma Exacerbations in Urban Children
- Conditions
- Asthma
- Interventions
- Biological: MepolizumabDrug: Placebo
- First Posted Date
- 2017-09-25
- Last Posted Date
- 2022-07-20
- Target Recruit Count
- 335
- Registration Number
- NCT03292588
- Locations
- 🇺🇸
Boston Medical Center, Boston, Massachusetts, United States
🇺🇸Children's National Medical Center, Washington, District of Columbia, United States
🇺🇸St. Louis Children's Hospital, Saint Louis, Missouri, United States
Safety and Immunogenicity of Clade C ALVAC and gp120 HIV Vaccine
- Conditions
- HIV Infections
- Interventions
- Biological: ALVAC-HIV (vCP2438)Biological: Bivalent Subtype C gp120Biological: Bivalent Subtype C gp120/MF59Biological: Bivalent Subtype C gp120 admixed with Al(OH)3 Suspension
- First Posted Date
- 2017-09-15
- Last Posted Date
- 2024-03-19
- Target Recruit Count
- 132
- Registration Number
- NCT03284710
- Locations
- 🇲🇿
Polana Canico Health Research and Training Center (CISPOC), National Institute of Health (INS) CRS, Maputo, Mozambique
🇿🇼Seke South CRS, Chitungwiza, Mashonaland East, Zimbabwe
🇿🇦Emavundleni CRS, Cape Town, Western Cape, South Africa
Natural History of Intestinal Inflammation in People With Primary Immune Dysregulations
- Conditions
- Chronic Granulomatous DiseaseInflammatory Bowel Disease
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
YCFM (Youth Correctional Facilities Males)
- First Posted Date
- 2017-08-15
- Last Posted Date
- 2019-10-28
- Target Recruit Count
- 100
- Registration Number
- NCT03249935
- Locations
- 🇺🇸
Los Angeles County Department of Health Services - Juvenile Court Health Services, Los Angeles, California, United States
Safety and Pharmacokinetic Study of Dapivirine Gel (0.05%) Administered Rectally to HIV-1 Seronegative Adults
- First Posted Date
- 2017-08-04
- Last Posted Date
- 2021-10-19
- Target Recruit Count
- 28
- Registration Number
- NCT03239483
- Locations
- 🇺🇸
University of Pittsburgh CRS, Pittsburgh, Pennsylvania, United States
🇹🇭Silom Community Clinic CRS, Nonthaburi, Bangkok, Thailand
🇺🇸Alabama CRS, Birmingham, Alabama, United States
Polyclonal Regulatory T Cells (PolyTregs) for Pemphigus
- Conditions
- Pemphigus VulgarisPemphigus Foliaceus
- First Posted Date
- 2017-08-04
- Last Posted Date
- 2024-02-15
- Target Recruit Count
- 5
- Registration Number
- NCT03239470
- Locations
- 🇺🇸
University of Iowa Health Care: Department of Dermatology, Iowa City, Iowa, United States
🇺🇸Duke University Medical Center: Department of Dermatology, Durham, North Carolina, United States
🇺🇸University of Texas Southwestern Medical Center: Department of Dermatology, Dallas, Texas, United States
Evaluating the Infectivity, Safety, and Immunogenicity of Recombinant Live-Attenuated RSV Vaccines RSV ΔNS2/Δ1313/I1314L or RSV 276 in RSV-Seronegative Infants 6 to 24 Months of Age
- Conditions
- Respiratory Syncytial Virus Infections
- Interventions
- Biological: RSV 276Biological: RSV ΔNS2/Δ1313/I1314LBiological: Placebo
- First Posted Date
- 2017-07-24
- Last Posted Date
- 2022-04-22
- Target Recruit Count
- 65
- Registration Number
- NCT03227029
- Locations
- 🇺🇸
Texas Children's Hospital CRS, Houston, Texas, United States
🇺🇸Usc La Nichd Crs, Los Angeles, California, United States
🇺🇸Johns Hopkins University Center for Immunization Research, Baltimore, Maryland, United States
Impact of a Short-Term Analytical Treatment Interruption and Re-Initiation of Antiretroviral Therapy on Immunologic and Virologic Parameters in HIV-Infected Individuals
- Conditions
- HIV
- First Posted Date
- 2017-07-21
- Last Posted Date
- 2020-01-18
- Target Recruit Count
- 29
- Registration Number
- NCT03225118
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Brentuximab Vedotin for Systemic Sclerosis
- Conditions
- SclerodermadcSScDiffuse Cutaneous Systemic Sclerosis
- Interventions
- Biological: PlaceboBiological: Brentuximab Vedotin
- First Posted Date
- 2017-07-19
- Last Posted Date
- 2024-05-17
- Target Recruit Count
- 17
- Registration Number
- NCT03222492
- Locations
- 🇺🇸
Duke University Medical Center: Division of Rheumatology and Immunology, Durham, North Carolina, United States
🇺🇸Medical University of South Carolina: Division of Rheumatology & Immunology, Charleston, South Carolina, United States
🇺🇸Hospital for Special Surgery, New York: Division of Rheumatology, New York, New York, United States