Evaluating the Pharmacokinetics, Safety, and Tolerability of Doravirine (MK-1439) and Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (MK-1439A) in HIV-1-Infected Children and Adolescents
- Conditions
- HIV Infections
- Interventions
- Drug: Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (DOR/3TC/TDF)Drug: Antiretroviral (ARV) medications
- First Posted Date
- 2017-11-06
- Last Posted Date
- 2023-02-14
- Target Recruit Count
- 55
- Registration Number
- NCT03332095
- Locations
- 🇹🇭
Siriraj Hospital ,Mahidol University NICHD CRS, Bangkok, Bangkoknoi, Thailand
🇹🇭Chiang Mai University HIV Treatment (CMU HIV Treatment) CRS, Chiang Mai, Thailand
🇺🇸Univ. of Colorado Denver NICHD CRS, Aurora, Colorado, United States
Bilateral Orthotopic Lung Transplant - Bone Marrow Transplant
- Conditions
- Primary ImmunodeficiencyPID
- Interventions
- Biological: CD3/CD19 neg allogeneic BMT
- First Posted Date
- 2017-11-06
- Last Posted Date
- 2024-04-03
- Target Recruit Count
- 5
- Registration Number
- NCT03330795
- Locations
- 🇺🇸
Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Age and Response to Flu Vaccines
- Conditions
- InfluenzaInfluenza Immunisation
- Interventions
- Biological: Influenza Virus Quadrivalent Inactivated Vaccine
- First Posted Date
- 2017-11-01
- Last Posted Date
- 2021-05-24
- Target Recruit Count
- 152
- Registration Number
- NCT03328325
- Locations
- 🇺🇸
Rochester General Hospital - Infectious Disease Unit, Rochester, New York, United States
🇺🇸University of Rochester Medical Center - Strong Memorial Hospital - Infectious Diseases, Rochester, New York, United States
Co-Administration of AS03 Adjuvanted A/H7N9 IIV With IIV4
- Conditions
- InfluenzaInfluenza ImmunisationAvian Influenza
- Interventions
- Biological: Inactivated influenza H7N9 vaccineBiological: Influenza Virus Quadrivalent Inactivated VaccineOther: Phosphate Buffered Saline (PBS) diluent
- First Posted Date
- 2017-10-23
- Last Posted Date
- 2020-08-06
- Target Recruit Count
- 149
- Registration Number
- NCT03318315
- Locations
- 🇺🇸
University of Maryland School of Medicine - Center for Vaccine Development - Baltimore, Baltimore, Maryland, United States
🇺🇸University of Alabama at Birmingham School of Medicine - Alabama Vaccine Research Clinic, Birmingham, Alabama, United States
🇺🇸Cincinnati Children's Hospital Medical Center - Infectious Diseases, Cincinnati, Ohio, United States
Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age With X-Linked Severe Combined Immunodeficiency
- Conditions
- X-Linked Combined Immunodeficiency Diseases
- Interventions
- Biological: CD34+ HSCs transduced with the lentivirus vector, VSV-G pseudotyped CL20-4i-EF1α-hγc-OPT
- First Posted Date
- 2017-10-19
- Last Posted Date
- 2019-12-04
- Target Recruit Count
- 13
- Registration Number
- NCT03315078
- Locations
- 🇺🇸
Laboratory of Host Defenses (LHD), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Maryland, United States
Sanofi 2017 H7N9 With/Without AS03 in Adults/Elderly
- Conditions
- Avian InfluenzaInfluenza Immunisation
- Interventions
- Biological: Inactivated influenza H7N9 vaccineOther: Phosphate Buffered Saline (PBS) diluent
- First Posted Date
- 2017-10-17
- Last Posted Date
- 2023-10-24
- Target Recruit Count
- 720
- Registration Number
- NCT03312231
- Locations
- 🇺🇸
Duke Vaccine and Trials Unit, Durham, North Carolina, United States
🇺🇸University of Iowa - Vaccine Research and Education Unit, Iowa City, Iowa, United States
🇺🇸The Hope Clinic of Emory University, Decatur, Georgia, United States
Molecular Basis of Erythrocyte Invasion by Plasmodium Vivax Into Duffy-Negative Erythrocytes in Mali
- Conditions
- Malaria
- First Posted Date
- 2017-10-09
- Last Posted Date
- 2023-10-31
- Target Recruit Count
- 667
- Registration Number
- NCT03304691
- Locations
- 🇲🇱
Yirimadio Community Health Center, Bamako, Mali
🇲🇱Bandiagara Malaria Program (BMP) Clinic, Bandiagara, Mali
Community Dynamics of Malaria Transmission and Mosquito Feeding in Bancoumana, Mali
- Conditions
- Malaria
- First Posted Date
- 2017-10-09
- Last Posted Date
- 2025-02-10
- Target Recruit Count
- 1928
- Registration Number
- NCT03304704
- Locations
- 🇲🇱
Doneguebougou Facility, Doneguebougou, Mali
🇲🇱Bancoumana Malaria Vaccine Center, Bamako, Mali
🇲🇱Univ of Sciences, Techniques and Technology, Bamako, Mali
PREDICT Cytomegalovirus (CMV)
- Conditions
- Lung Transplant
- Interventions
- Other: Procedure
- First Posted Date
- 2017-10-04
- Last Posted Date
- 2020-08-06
- Target Recruit Count
- 84
- Registration Number
- NCT03300882
- Locations
- 🇺🇸
Johns Hopkins Hospital: Transplantation, Baltimore, Maryland, United States
🇨🇦Toronto General Hospital: Transplantation, Toronto, Canada
🇺🇸Duke University Medical Center: Transplantation, Durham, North Carolina, United States
Asymptomatic Congenital CMV Treatment
- First Posted Date
- 2017-10-04
- Last Posted Date
- 2023-01-26
- Target Recruit Count
- 7
- Registration Number
- NCT03301415
- Locations
- 🇺🇸
University of Alabama - Children's of Alabama - Clinical Virology, Birmingham, Alabama, United States
🇺🇸Arkansas Children's Hospital - Infectious Diseases, Little Rock, Arkansas, United States
🇺🇸University of Louisville School of Medicine - Norton Children's Hospital - Infectious Diseases, Louisville, Kentucky, United States