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NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

๐Ÿ‡บ๐Ÿ‡ธUnited States
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Safety Study of SLV213 for the Treatment of COVID-19.

Phase 1
Terminated
Conditions
COVID-19
Interventions
Other: Placebo for SLV213
Drug: SLV213
First Posted Date
2023-11-24
Last Posted Date
2024-10-03
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
16
Registration Number
NCT06146374
Locations
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Altasciences Inc - Kansas City, Overland Park, Kansas, United States

Protocol CAUSE-03 / CHEETAH

Recruiting
Conditions
Asthma
First Posted Date
2023-11-18
Last Posted Date
2024-05-06
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
310
Registration Number
NCT06136091
Locations
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Children's Hospital Colorado: Allergy Program, Aurora, Colorado, United States

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Children's National Medical Center: Children's Research Institute, Washington, District of Columbia, United States

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Boston University School of Medicine: Pulmonary Center, Boston, Massachusetts, United States

and more 5 locations

A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus

Phase 1
Recruiting
Conditions
Congenital Cytomegalovirus Infection
Interventions
First Posted Date
2023-11-07
Last Posted Date
2025-01-03
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
12
Registration Number
NCT06118515
Locations
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Medical College of Wisconsin, Milwaukee, Wisconsin, United States

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Children's of Alabama Child Health Research Unit (CHRU), Birmingham, Alabama, United States

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Children's National Medical Center - Sheikh Zayed Campus - Infectious Disease, Washington, District of Columbia, United States

and more 7 locations

Establishment of Biobank of Nasal Epithelium Samples From Healthy Volunteers

Recruiting
Conditions
Healthy
First Posted Date
2023-11-07
Last Posted Date
2024-12-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
120
Registration Number
NCT06120244
Locations
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Rocky Mountain Laboratories, Hamilton, Montana, United States

Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates

Phase 2
Recruiting
Conditions
Liver Transplant
Interventions
Drug: CMV-MVA Triplex
Drug: Placebo for CMV-MVA Triplex
First Posted Date
2023-10-10
Last Posted Date
2024-12-27
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
416
Registration Number
NCT06075745
Locations
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University of Alabama at Birmingham, School of Medicine, Birmingham, Alabama, United States

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University of California, San Diego School of Medicine, La Jolla, California, United States

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Stanford University, Redwood City, California, United States

and more 15 locations

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

Phase 1
Recruiting
Conditions
HIV-1-infection
Interventions
Biological: Placebo
Biological: ChAdOx1.tHIVconsv1
Biological: ChAdOx1.HIVconsv62
Biological: MVA.tHIVconsv3
Biological: MVA.tHIVconsv4
Drug: Vesatolimod (VES)
Drug: GS-5423
Drug: GS-2872
First Posted Date
2023-10-06
Last Posted Date
2024-04-09
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
45
Registration Number
NCT06071767
Locations
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Ponce de Leon Center CRS, Atlanta, Georgia, United States

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Penn Therapeutics CRS, Philadelphia, Pennsylvania, United States

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Columbia Physicians & Surgeons CRS, New York, New York, United States

and more 10 locations

Advancing Transplantation Outcomes in Children

Phase 2
Recruiting
Conditions
Kidney Transplant
Interventions
First Posted Date
2023-09-28
Last Posted Date
2024-12-10
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
200
Registration Number
NCT06055608
Locations
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University of Alabama at Birmingham (Site # 71038), Birmingham, Alabama, United States

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Children's Hospital of Los Angeles (Site #: 71036), Los Angeles, California, United States

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Cedars-Sinai Medical Center (Site #: 71026), Los Angeles, California, United States

and more 18 locations

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

Phase 1
Recruiting
Conditions
End Stage Renal Failure on Dialysis
Kidney Failure
Kidney Transplant
Interventions
Drug: Cyclophosphamide
Biological: CART-BCMA
Biological: huCART19
Drug: Fludarabine
First Posted Date
2023-09-28
Last Posted Date
2025-01-08
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
20
Registration Number
NCT06056102
Locations
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NYU Langone Health (Site #: 71177), New York, New York, United States

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Massachusetts General Hospital: Transplantation (Site #: 71107), Boston, Massachusetts, United States

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University of Pennsylvania Medical Center (Site #: 71111), Philadelphia, Pennsylvania, United States

A Trial to Evaluate an HIV Envelope Trimer, N332-GT5 gp140, Adjuvanted With SMNP in Adult Participants Without HIV

Phase 1
Recruiting
Conditions
HIV
Interventions
Biological: N332-GT5 gp140 (IM, Bolus)
Biological: N332-GT5 gp140 (SC, Bolus)
Biological: N332-GT5 gp140 (IM, Fractioned)
Biological: N332-GT5 gp140 (SC, Fractioned)
Biological: SMNP (IM, Bolus)
Biological: SMNP (SC, Bolus)
Biological: SMNP (IM, Fractioned)
Biological: SMNP (SC, Fractioned)
First Posted Date
2023-09-13
Last Posted Date
2024-11-05
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
84
Registration Number
NCT06033209
Locations
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Bridge HIV CRS, San Francisco, California, United States

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UCSF School of Medicine, San Francisco, California, United States

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Atlanta - Hope Clinic, Decatur, Georgia, United States

and more 6 locations

Tocilizumab in Lung Transplantation

Phase 2
Recruiting
Conditions
Lung Transplant
Interventions
First Posted Date
2023-09-13
Last Posted Date
2024-12-24
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
350
Registration Number
NCT06033196
Locations
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St. Joseph's Hospital and Medical Center (Site #: 71192), Phoenix, Arizona, United States

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Cedars Sinai Medical Center (Site #: 71146), Los Angeles, California, United States

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David Geffen School of Medicine at UCLA (Site #: 71123), Los Angeles, California, United States

and more 12 locations
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