MedPath

AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Aclidinium Bromide Post-Authorisation Safety Study to Evaluate the Risk of Cardiovascular Endpoints

Completed
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Drug: Other COPD medication
First Posted Date
2017-09-21
Last Posted Date
2023-01-31
Lead Sponsor
AstraZeneca
Target Recruit Count
26839
Registration Number
NCT03290287
Locations
🇬🇧

Clinical Practice Research Datalink, London, United Kingdom

To Study Clinical Effectiveness and Safety of Olaparib Monotherapy in Metastatic Breast Cancer Patients.

Phase 3
Completed
Conditions
Somatic BRCA1/2 Mutations
HER2-ve Metastatic Breast Cancer
Germline BRCA1/2 Mutations
Interventions
First Posted Date
2017-09-19
Last Posted Date
2023-01-17
Lead Sponsor
AstraZeneca
Target Recruit Count
256
Registration Number
NCT03286842
Locations
🇬🇧

Research Site, Sutton, United Kingdom

A Safety and Pharmacodynamic Study of Healthy Chinese Subjects Administered Sodium Zirconium Cyclosilicate (ZS)

Phase 1
Completed
Conditions
Hyperkalemia
Interventions
Drug: Sodium Zirconium Cyclosilicate (ZS)
First Posted Date
2017-09-14
Last Posted Date
2017-12-19
Lead Sponsor
AstraZeneca
Target Recruit Count
22
Registration Number
NCT03283267
Locations
🇭🇰

Research Site, Hong Kong, Hong Kong

Pharmacokinetics, Safety and Tolerability of Twice-Daily Aclidinium Bromide/Formoterol Fumarate Fixed Dose Combination in Chinese Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Phase 2
Completed
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
First Posted Date
2017-09-08
Last Posted Date
2019-07-22
Lead Sponsor
AstraZeneca
Target Recruit Count
20
Registration Number
NCT03276078
Locations
🇨🇳

Research Site, Changchun, China

A Phase I, Open-Label, Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Aclidinium Bromide in Healthy Chinese Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2017-09-08
Last Posted Date
2023-12-11
Lead Sponsor
AstraZeneca
Target Recruit Count
20
Registration Number
NCT03276052
Locations
🇨🇳

Research Site, Chengdu, China

To Assess the Pharmacokinetics, Safety and Tolerability of Abediterol Administered Once Daily for 9 Days, in Patients With Asthma on Inhaled Corticosteroids

Phase 1
Completed
Conditions
Asthma
Interventions
Drug: Placebo
First Posted Date
2017-09-06
Last Posted Date
2017-11-27
Lead Sponsor
AstraZeneca
Target Recruit Count
12
Registration Number
NCT03273127
Locations
🇩🇪

Research Site, Berlin, Germany

Single Ascending Dose Study of MEDI1341 in Healthy Volunteers

Phase 1
Completed
Conditions
Parkinson's Disease
Interventions
Drug: Placebo
First Posted Date
2017-09-05
Last Posted Date
2022-06-09
Lead Sponsor
AstraZeneca
Target Recruit Count
50
Registration Number
NCT03272165
Locations
🇺🇸

Research Site, Madison, Wisconsin, United States

Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

Phase 1
Completed
Conditions
High Risk Myelodysplastic Syndrome
T-cell Non-Hodgkin Lymphoma
Relapsed or Refractory Haematological Malignancies Including
Acute Myeloid Leukemia
Acute Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Chronic Myelomonocytic Leukemia
Richter's Syndrome
B-cell Non-Hodgkin Lymphoma
Chronic Lymphocytic Leukemia
Interventions
First Posted Date
2017-08-28
Last Posted Date
2021-10-22
Lead Sponsor
AstraZeneca
Target Recruit Count
44
Registration Number
NCT03263637
Locations
🇬🇧

Research Site, Sutton, United Kingdom

An Intermediate Access Protocol for Selumetinib for Treatment of Neurofibromatosis Type 1

Conditions
NF type1 With Inoperable Plexiform Neurofibromas
First Posted Date
2017-08-24
Last Posted Date
2020-05-01
Lead Sponsor
AstraZeneca
Registration Number
NCT03259633
Locations
🇺🇸

Research Site, New Orleans, Louisiana, United States

A Study to Investigate the Effect of Single Dose of AZD6094 (600 mg) on Cardiac Repolarization in Healthy Volunteers

Phase 1
Completed
Conditions
Solid Tumors
Interventions
Drug: AZD6094 200 mg
Other: Placebo
First Posted Date
2017-08-23
Last Posted Date
2020-02-20
Lead Sponsor
AstraZeneca
Target Recruit Count
45
Registration Number
NCT03258515
Locations
🇺🇸

Research Site, Baltimore, Maryland, United States

© Copyright 2025. All Rights Reserved by MedPath