MedPath

AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Study to Determine the Effect of Food on the Blood Levels of AZD9291 Following Oral Dosing of a Tablet Formulation in Patients With Non-Small Cell Lung Cancer

Phase 1
Completed
Conditions
Advanced Non Small Cell Lung Cancer
Advanced (Inoperable) Non Small Cell Lung Cancer
Interventions
Drug: AZD9291 tablets
Procedure: Pharmacokinetic sampling - AZD9291
Other: Dietary Fasted
Other: Dietary High Fat
Procedure: Pharmacokinetic sampling - AZ5140 and AZ7550
First Posted Date
2014-06-16
Last Posted Date
2024-01-22
Lead Sponsor
AstraZeneca
Target Recruit Count
38
Registration Number
NCT02163733
Locations
🇬🇧

Research Site, Sutton, United Kingdom

Study to Assess the Blood Levels and Safety of AZD9291 in Patients With Advanced Solid Tumours and Normal Liver Function or Mild or Moderate Liver Impairment

Phase 1
Completed
Conditions
Solid Tumours
Interventions
Drug: AZD9291 tablet dosing
Procedure: Pharmacokinetic sampling - AZD9291
Procedure: Pharmacokinetic sampling - AZ5140 and AZ7550
First Posted Date
2014-06-12
Last Posted Date
2019-03-08
Lead Sponsor
AstraZeneca
Target Recruit Count
30
Registration Number
NCT02161770
Locations
🇬🇧

Research Site, Newcastle Upon Tyne, United Kingdom

A Phase 3 Study to Evaluate the Efficacy and Safety of Tralokinumab in Adults and Adolescents With Uncontrolled Asthma

Phase 3
Completed
Conditions
Uncontrolled Asthma
Interventions
Biological: Tralokinumab
Other: Placebo
First Posted Date
2014-06-12
Last Posted Date
2018-08-28
Lead Sponsor
AstraZeneca
Target Recruit Count
1207
Registration Number
NCT02161757
Locations
🇻🇳

Research Site, Hochiminh, Vietnam

Comparing the Efficacy of Symbicort® pMDI and Formoterol Turbuhaler in Reducing Exacerbations in Patients With Cronic Obstructive Pulmonary Disease

Phase 3
Completed
Conditions
COPD Patients
Interventions
Other: Placebo for Symbicort pMDI
Other: Placebo for Formoterol Turbohaler
First Posted Date
2014-06-06
Last Posted Date
2017-11-07
Lead Sponsor
AstraZeneca
Target Recruit Count
2026
Registration Number
NCT02157935
Locations
🇪🇸

Research Site, Zaragoza, Spain

Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD9291, in Patients With EGFR Positive Non-small Cell Lung Cancer. Patients Will be Chosen From Those Who Have Already Been Prescribed an EGFR TKI Medicine (Such as Iressa or Tarceva)

Phase 1
Completed
Conditions
Advanced Non Small Cell Lung Cancer
Advanced (Inoperable) Non Small Cell Lung Cancer
Interventions
Procedure: Pharmacokinetic sampling
First Posted Date
2014-06-06
Last Posted Date
2024-03-19
Lead Sponsor
AstraZeneca
Target Recruit Count
39
Registration Number
NCT02157883
Locations
🇬🇧

Research Site, Manchester, United Kingdom

Phase IV Study With a 36-week Extension Period to Evaluate the Efficacy and Safety of Dapagliflozin Therapy When Added to the Therapy of Japanese Patients With Type 2 Diabetes With Inadequate Glycemic Control on Insulin.

Phase 4
Completed
Conditions
Type 2 Diabetes Mellitus
Interventions
Drug: Placebo tablet
First Posted Date
2014-06-06
Last Posted Date
2016-05-11
Lead Sponsor
AstraZeneca
Target Recruit Count
266
Registration Number
NCT02157298
Locations
🇯🇵

Research Site, Yokohama-shi, Japan

Stress Ulcer Prophylaxis of Intravenous Esomeprazole in Chinese Seriously Ill Patients

Phase 3
Completed
Conditions
Stress Ulcer Prophylaxis
Interventions
First Posted Date
2014-06-06
Last Posted Date
2017-03-10
Lead Sponsor
AstraZeneca
Target Recruit Count
343
Registration Number
NCT02157376
Locations
🇨🇳

Research Site, Zhanjiang, China

Efficacy and Safety of Ciclesonide Nasal Spray in Participants With Seasonal Allergic Rhinitis (SAR) in Russia

Phase 3
Completed
Conditions
Seasonal Allergic Rhinitis
Interventions
First Posted Date
2014-06-04
Last Posted Date
2017-02-02
Lead Sponsor
AstraZeneca
Target Recruit Count
80
Registration Number
NCT02155881

Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With Exacerbation History

Phase 3
Completed
Conditions
Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Interventions
First Posted Date
2014-06-04
Last Posted Date
2019-06-26
Lead Sponsor
AstraZeneca
Target Recruit Count
2255
Registration Number
NCT02155660
Locations
🇻🇳

Research Site, Ho Chi Minh, Vietnam

Non-Interventional Study PREVENT

Completed
Conditions
Postoperative or Postradiation Adjuvant Androgen Deprivation Therapy in Locally Advanced Prostate Cancer (High and Very High Risk) Patients
First Posted Date
2014-06-04
Last Posted Date
2019-04-11
Lead Sponsor
AstraZeneca
Target Recruit Count
200
Registration Number
NCT02155998
Locations
🇷🇺

Research Site, Vladimir, Russian Federation

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