MedPath

AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Validating Artificial Intelligence Effectiveness Defined Lung Nodule Malignancy Score in Patients With Pulmonary Nodule.

Active, not recruiting
Conditions
Lung Malignancy
Interventions
Other: Participant Cohort
First Posted Date
2023-04-18
Last Posted Date
2025-05-21
Lead Sponsor
AstraZeneca
Target Recruit Count
700
Registration Number
NCT05817110
Locations
🇹🇷

Research Site, Mersin, Turkey

An ADME Study of [14C]AZD0780 in Healthy Male Subjects

Phase 1
Completed
Conditions
Cardiovascular Diseases
Interventions
Drug: AZD0780 tablet
Drug: [14C]AZD0780 Solution for Infusion
Drug: [14C]AZD0780 Oral Solution
First Posted Date
2023-04-18
Last Posted Date
2023-08-09
Lead Sponsor
AstraZeneca
Target Recruit Count
8
Registration Number
NCT05817461
Locations
🇬🇧

Research Site, Ruddington, United Kingdom

A Study to Evaluate AZD2693 in Participants Who Are Carriers of the PNPLA3 148M Risk Allele With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

Phase 2
Active, not recruiting
Conditions
Nonalcoholic Steatohepatitis
Interventions
Other: Placebo
First Posted Date
2023-04-12
Last Posted Date
2025-04-23
Lead Sponsor
AstraZeneca
Target Recruit Count
175
Registration Number
NCT05809934
Locations
🇻🇳

Research Site, Ho Chi Minh, Vietnam

A Study to Investigate Safety and Efficacy of Osimertinib and Amivantamab in Participants With Non-small Cell Lung Cancer With Common Epidermal Growth Factor Receptor Mutations

Phase 2
Active, not recruiting
Conditions
Non-Small Cell Lung Cancer (NSCLC)
Interventions
First Posted Date
2023-04-06
Last Posted Date
2025-03-27
Lead Sponsor
AstraZeneca
Target Recruit Count
60
Registration Number
NCT05801029
Locations
🇹🇭

Research Site, Songkhla, Thailand

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

Phase 1
Recruiting
Conditions
Ovarian Cancer
Lung Adenocarcinoma
Interventions
First Posted Date
2023-04-04
Last Posted Date
2025-04-08
Lead Sponsor
AstraZeneca
Target Recruit Count
396
Registration Number
NCT05797168
Locations
🇬🇧

Research Site, Sutton, United Kingdom

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Elarekibep in Healthy Japanese Subjects

Phase 1
Terminated
Conditions
Healthy Subjects (Indication: Asthma)
Interventions
Drug: Placebo
First Posted Date
2023-04-03
Last Posted Date
2023-07-18
Lead Sponsor
AstraZeneca
Target Recruit Count
30
Registration Number
NCT05794672
Locations
🇬🇧

Research Site, Harrow, United Kingdom

Study to Investigate Hepatic Impairment on PK, Safety, Tolerability of Camizestrant in Post-Menopausal Female Subjects

Phase 1
Completed
Conditions
Hepatic Impairment
Interventions
First Posted Date
2023-03-30
Last Posted Date
2025-03-25
Lead Sponsor
AstraZeneca
Target Recruit Count
22
Registration Number
NCT05790304
Locations
🇸🇰

Research Site, Bratislava, Slovakia

A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin.

Phase 1
Completed
Conditions
Dyslipidemia
Interventions
First Posted Date
2023-03-28
Last Posted Date
2025-04-27
Lead Sponsor
AstraZeneca
Target Recruit Count
16
Registration Number
NCT05787002
Locations
🇺🇸

Research Site, Brooklyn, Maryland, United States

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Phase 3
Recruiting
Conditions
Breast Cancer, Early Breast Cancer
Interventions
First Posted Date
2023-03-20
Last Posted Date
2025-05-18
Lead Sponsor
AstraZeneca
Target Recruit Count
4300
Registration Number
NCT05774951
Locations
🇻🇳

Research Site, Hue, Vietnam

A Study to Characterize the Outcomes of Olaparib Maintenance Monotherapy in Newly Diagnosed BRCAwt Ovarian Cancer

Completed
Conditions
Advanced Ovarian Cancer
Interventions
Other: None (Observational Study)
First Posted Date
2023-03-20
Last Posted Date
2023-11-30
Lead Sponsor
AstraZeneca
Target Recruit Count
24
Registration Number
NCT05775549
Locations
🇺🇸

Research Site, Madison, Wisconsin, United States

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