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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer

Phase 2
Recruiting
Conditions
Hepatocellular Carcinoma
Biliary Tract Cancer
Interventions
First Posted Date
2023-03-20
Last Posted Date
2025-05-30
Lead Sponsor
AstraZeneca
Target Recruit Count
260
Registration Number
NCT05775159
Locations
🇬🇧

Research Site, Manchester, United Kingdom

A Study to Assess the Effects of Savolitinib on the Pharmacokinetics of Digoxin, Rosuvastatin, Metformin, and Furosemide in Healthy Male Subjects

First Posted Date
2023-03-14
Last Posted Date
2023-07-13
Lead Sponsor
AstraZeneca
Target Recruit Count
6
Registration Number
NCT05768360
Locations
🇩🇪

Research Site, Berlin, Germany

A 12-week Study to Assess the Efficacy and Safety of Budesonide and Formoterol Fumarate Metered Dose Inhaler Relative to Budesonide Metered Dose Inhaler in Participants With Inadequately Controlled Asthma (LITHOS)

Phase 3
Completed
Conditions
Asthma
Interventions
Drug: BFF MDI 160/9.6 μg BID (320/19.2μg/day)
First Posted Date
2023-03-06
Last Posted Date
2024-12-11
Lead Sponsor
AstraZeneca
Target Recruit Count
373
Registration Number
NCT05755906
Locations
🇿🇦

Research Site, Tygervalley, South Africa

Study to Assess Effect of HFO MDI Propellant on Mucociliary Clearance Vs. HFA MDI Propellant in Healthy Participants

Phase 3
Completed
Conditions
Mucociliary Clearance
Interventions
Drug: HFO MDI
Drug: HFA MDI
First Posted Date
2023-03-06
Last Posted Date
2024-07-26
Lead Sponsor
AstraZeneca
Target Recruit Count
35
Registration Number
NCT05755932
Locations
🇬🇧

Research Site, Glasgow, United Kingdom

Pharmacokinetics of Mitiperstat in Participants With Hepatic Impairment

Phase 1
Completed
Conditions
Hepatic Impairment
Interventions
First Posted Date
2023-03-02
Last Posted Date
2024-12-05
Lead Sponsor
AstraZeneca
Target Recruit Count
31
Registration Number
NCT05751759
Locations
🇺🇸

Research Site, San Antonio, Texas, United States

Long-term Efficacy and Safety of Tozorakimab in Participants With Chronic Obstructive Pulmonary Disease With a History of Exacerbations (PROSPERO).

Phase 3
Recruiting
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Combination Product: Placebo
Combination Product: Tozorakimab 1
Combination Product: Tozorakimab 2
First Posted Date
2023-02-24
Last Posted Date
2025-05-23
Lead Sponsor
AstraZeneca
Target Recruit Count
1596
Registration Number
NCT05742802
Locations
🇻🇳

Research Site, Ho Chi Minh, Vietnam

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2

Phase 2
Active, not recruiting
Conditions
Pulmonary Hypertension (World Health Organization Group 2)
Heart Failure
Interventions
Drug: Placebo
First Posted Date
2023-02-21
Last Posted Date
2025-05-13
Lead Sponsor
AstraZeneca
Target Recruit Count
260
Registration Number
NCT05737940
Locations
🇬🇧

Research Site, London, United Kingdom

Patient-Reported Outcomes of Benralizumab in Real-World Use in Severe Eosinophilic Asthma Patients in Taiwan (BEAT)

Completed
Conditions
Asthma
First Posted Date
2023-02-17
Last Posted Date
2025-03-07
Lead Sponsor
AstraZeneca
Target Recruit Count
43
Registration Number
NCT05734339
Locations
🇨🇳

Research Site, Taoyuan City, Taiwan

TEZSPIRE (Tezepelumab) Asthma Japan Post-Marketing Study (PMS)

Recruiting
Conditions
Bronchial Asthma (Only the Patients With Severe or Intractable Bronchial Asthma Which Could Not be Controlled With the Existing Therapy)
First Posted Date
2023-02-15
Last Posted Date
2025-05-01
Lead Sponsor
AstraZeneca
Target Recruit Count
400
Registration Number
NCT05729711
Locations
🇯🇵

Research Site, Yamanashi, Japan

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