MedPath

AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

A Study to Assess the Safety of Budesonide/Glycopyrronium/Formoterol Fumarate With the Hydrofluoroolefin Propellant in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

Phase 3
Completed
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Drug: BGF MDI HFO 320/14.4/9.6 μg
Drug: BGF MDI HFA 320/14.4/9.6 μg
First Posted Date
2022-10-10
Last Posted Date
2025-03-27
Lead Sponsor
AstraZeneca
Target Recruit Count
559
Registration Number
NCT05573464
Locations
🇬🇧

Research Site, Thetford, United Kingdom

PROVIDENCE - Prospective Non-interventional Study (NIS) to Examine Patient-reported Outcomes and Real-world Clinical Data in Patients With HER2-positive, HER2-low or HER2-ultralow Unresectable or Metastatic Breast Cancer Treated With Trastuzumab Deruxtecan

Recruiting
Conditions
Breast Neoplasms
Breast Cancer
Neoplasm Metastasis
First Posted Date
2022-10-10
Last Posted Date
2025-05-14
Lead Sponsor
AstraZeneca
Target Recruit Count
800
Registration Number
NCT05573893
Locations
🇩🇪

Research Site, Zittau, Germany

Drug-drug Interaction Study With AZD5305 and Itraconazole in Patients With Advanced Solid Malignancies

Phase 1
Completed
Conditions
Advanced Solid Malignancies
Interventions
First Posted Date
2022-10-10
Last Posted Date
2024-06-18
Lead Sponsor
AstraZeneca
Target Recruit Count
16
Registration Number
NCT05573724
Locations
🇷🇴

Research Site, Cluj-Napoca, Romania

A Study to Assess the Total Systemic Exposure Bioequivalence of of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA

Phase 1
Completed
Conditions
Chronic Obstructive Pulmonary Disease
First Posted Date
2022-10-06
Last Posted Date
2025-04-29
Lead Sponsor
AstraZeneca
Target Recruit Count
108
Registration Number
NCT05569421
Locations
🇺🇸

Research Site, Glendale, California, United States

eVusheld Assessment reaL wORld Effectiveness in DoD Health System

Not yet recruiting
Conditions
COVID-19; SARS-CoV-2; 2019 Novel Coronavirus Disease
Interventions
First Posted Date
2022-10-06
Last Posted Date
2023-09-22
Lead Sponsor
AstraZeneca
Target Recruit Count
6000
Registration Number
NCT05569408
Locations
🇺🇸

Research Site, Bethesda, Maryland, United States

Knockdown of HSD17B13 mRNA, Pharmacokinetics, Safety, and Tolerability, of AZD7503 in Non-Alcoholic Fatty Liver Disease

Phase 1
Completed
Conditions
NAFLD
Nonalcoholic Fatty Liver Disease
Nonalcoholic Steatohepatitis
NASH
Non-alcoholic Fatty Liver Disease
Fatty Liver, Nonalcoholic
Interventions
Drug: AZD7503 Intervention
First Posted Date
2022-09-29
Last Posted Date
2024-03-18
Lead Sponsor
AstraZeneca
Target Recruit Count
19
Registration Number
NCT05560607
Locations
🇺🇸

Research Site, San Antonio, Texas, United States

Study of Durvalumab Plus Tremelimumab as First-line Treatment in Chinese Patients With Unresectable Hepatocellular Carinoma

Phase 3
Recruiting
Conditions
Hepatocellular Carcinoma
Interventions
First Posted Date
2022-09-28
Last Posted Date
2025-02-07
Lead Sponsor
AstraZeneca
Target Recruit Count
210
Registration Number
NCT05557838
Locations
🇨🇳

Research Site, Zhengzhou, China

Observational Study of Acalabrutinib in Patients With Chronic Lymphocytic Leukaemia in the United Kingdom

Recruiting
Conditions
Chronic Lymphocytic Leukemia, CLL
Interventions
First Posted Date
2022-09-28
Last Posted Date
2025-04-27
Lead Sponsor
AstraZeneca
Target Recruit Count
350
Registration Number
NCT05557695
Locations
🇬🇧

Research Site, Wigan, United Kingdom

PT027 Compared to PT007 in Patients With Asthma With Mannitol-induced Acute Airway Obstruction

Phase 3
Completed
Conditions
Asthma
Interventions
Combination Product: PT027
Combination Product: PT007
First Posted Date
2022-09-26
Last Posted Date
2025-01-08
Lead Sponsor
AstraZeneca
Target Recruit Count
21
Registration Number
NCT05555290
Locations
🇺🇸

Research Site, Columbia, Maryland, United States

A Study to Assess the Pharmacokinetics of Camizestrant (AZD9833) When Administered Alone and in Combination With Itraconazole

Phase 1
Completed
Conditions
Healthy Subjects
Interventions
First Posted Date
2022-09-23
Last Posted Date
2023-01-06
Lead Sponsor
AstraZeneca
Target Recruit Count
14
Registration Number
NCT05551897
Locations
🇬🇧

Research Site, Harrow, United Kingdom

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