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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Real-world Dapagliflozin Treatment in Patients With Heart Failure in Portugal (EVOLUTION-HF)

Completed
Conditions
Heart Failure
First Posted Date
2022-07-19
Last Posted Date
2025-06-06
Lead Sponsor
AstraZeneca
Target Recruit Count
283
Registration Number
NCT05465213
Locations
🇵🇹

Research Site, Vila Real, Portugal

Safety of Oral Resin for Treatment of Hyperkalemia in Chinese Patients With Renal Insufficiency

Completed
Conditions
Hyperkalaemia
First Posted Date
2022-07-18
Last Posted Date
2024-12-03
Lead Sponsor
AstraZeneca
Target Recruit Count
887
Registration Number
NCT05462119
Locations
🇨🇳

Peking University People's Hospital, Beijing, Beijing, China

🇨🇳

Research Site, Zhengzhou, China

Open-Label Extension Study of Patients Previously Enrolled in Study CIN-107-124

Phase 2
Completed
Conditions
Hypertension
Interventions
First Posted Date
2022-07-15
Last Posted Date
2024-12-16
Lead Sponsor
AstraZeneca
Target Recruit Count
175
Registration Number
NCT05459688
Locations
🇺🇸

Research Site, Manassas, Virginia, United States

A Study of Dato-DXd in Chinese Patients With Advanced Non-Small Cell Lung Cancer, Triple-negative Breast Cancer and Other Solid Tumors (TROPION-PanTumor02)

Phase 1
Active, not recruiting
Conditions
Carcinoma, Non-Small-Cell Lung
Triple Negative Breast Cancer
Interventions
Drug: Datopotamab Deruxtecan (Dato-DXd)
First Posted Date
2022-07-15
Last Posted Date
2024-04-17
Lead Sponsor
AstraZeneca
Target Recruit Count
119
Registration Number
NCT05460273
Locations
🇨🇳

Research Site, Wuhan, China

A Study to Assess the Relative Bioavailability and Safety of Different Formulations of AZD4831 in Fasted State in Healthy Volunteers.

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2022-07-13
Last Posted Date
2022-11-01
Lead Sponsor
AstraZeneca
Target Recruit Count
30
Registration Number
NCT05457270
Locations
🇺🇸

Research Site, Brooklyn, Maryland, United States

Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Prior Treatment With a New Hormonal Agent and Have BRCA1/2 Mutations

Phase 4
Active, not recruiting
Conditions
Metastatic Castration-resistant Prostate Cancer
Interventions
First Posted Date
2022-07-13
Last Posted Date
2025-05-14
Lead Sponsor
AstraZeneca
Target Recruit Count
43
Registration Number
NCT05457257
Locations
🇨🇳

Research Site, Zhengzhou, China

A Multi-center, Non-interventional, Prospective Study of Durvalumab in Unresectable Locally Advanced NSCLC in Routine Clinical Practice in Russia

Recruiting
Conditions
NSCLC, Non-small-cell Lung Carcinoma
First Posted Date
2022-07-13
Last Posted Date
2024-10-01
Lead Sponsor
AstraZeneca
Target Recruit Count
250
Registration Number
NCT05456867
Locations
🇷🇺

Research Site, Yuzhno-Sakhalinsk, Russian Federation

Ondexxya for Intravenous Injection 200mg Drug Use Result Investigation (All Case Investigation)

Recruiting
Conditions
Life Threatening Bleeding
Factor Xa Inhibitor
First Posted Date
2022-07-12
Last Posted Date
2025-05-31
Lead Sponsor
AstraZeneca
Target Recruit Count
300
Registration Number
NCT05454787
Locations
🇯🇵

Research Site, Yamanashi, Japan

AZD7798 Safety, Tolerability, and Pharmacokinetics After a Single Ascending and Repeat Dose Administrations to Healthy Subjects, and Patients With Crohn's Disease

Phase 1
Completed
Conditions
Crohns Disease
Healthy Subjects
Interventions
Biological: Placebo
First Posted Date
2022-07-11
Last Posted Date
2025-02-06
Lead Sponsor
AstraZeneca
Target Recruit Count
112
Registration Number
NCT05452304
Locations
🇬🇧

Research Site, Harrow, United Kingdom

A Phase III Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Non Small Cell Lung Cancer (NSCLC) Whose Disease Progressed On or After Prior Anti PD (L)1 Therapy And Platinum Based Chemotherapy

Phase 3
Active, not recruiting
Conditions
Advanced or Metastatic Non-Small Cell Lung Cancer
Interventions
First Posted Date
2022-07-11
Last Posted Date
2025-03-21
Lead Sponsor
AstraZeneca
Target Recruit Count
594
Registration Number
NCT05450692
Locations
🇬🇧

Research Site, Wirral, United Kingdom

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