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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Tracking Treatment Pathways in Adult Patients With Hyperkalemia.

Completed
Conditions
Hyperkalemia
First Posted Date
2022-06-07
Last Posted Date
2025-01-06
Lead Sponsor
AstraZeneca
Target Recruit Count
1331
Registration Number
NCT05408039
Locations
🇬🇧

Research Site, Stevenage, United Kingdom

A First-in-human Study to Evaluate the Safety and Tolerability of AZD8853 in Participants With Selected Advanced/Metastatic Solid Tumours

Phase 1
Terminated
Conditions
Urinary Bladder Neoplasms
Colorectal Cancer
Carcinoma, Non-Small-Cell Lung
Interventions
First Posted Date
2022-05-31
Last Posted Date
2024-10-01
Lead Sponsor
AstraZeneca
Target Recruit Count
17
Registration Number
NCT05397171
Locations
🇨🇦

Research Site, Toronto, Ontario, Canada

Tezepelumab Efficacy and Safety in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma

Phase 3
Terminated
Conditions
Asthma
Interventions
First Posted Date
2022-05-31
Last Posted Date
2025-04-09
Lead Sponsor
AstraZeneca
Target Recruit Count
125
Registration Number
NCT05398263
Locations
🇹🇷

Research Site, Izmir, Turkey

A Study to Assess the Effect of AZD5462 on the Pharmacokinetics of Midazolam, Rosuvastatin and Digoxin

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2022-05-27
Last Posted Date
2023-12-13
Lead Sponsor
AstraZeneca
Target Recruit Count
32
Registration Number
NCT05395117
Locations
🇺🇸

Research Site, Brooklyn, Maryland, United States

PASS of Paediatric Patients Initiating Selumetinib

Recruiting
Conditions
Neurofibromatosis Type 1
First Posted Date
2022-05-24
Last Posted Date
2025-06-03
Lead Sponsor
AstraZeneca
Target Recruit Count
125
Registration Number
NCT05388370
Locations
🇬🇧

Research Site, Newcastle, United Kingdom

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects

Phase 1
Completed
Conditions
Dyslipidemia
Interventions
First Posted Date
2022-05-20
Last Posted Date
2024-07-19
Lead Sponsor
AstraZeneca
Target Recruit Count
183
Registration Number
NCT05384262
Locations
🇬🇧

Research Site, Harrow, United Kingdom

FAsenra Safety Trial in India

Phase 4
Completed
Conditions
In Adult Patients of Severe Asthma With Eosinophilic Phenotype in India
Interventions
First Posted Date
2022-05-20
Last Posted Date
2024-12-11
Lead Sponsor
AstraZeneca
Target Recruit Count
139
Registration Number
NCT05384938
Locations
🇮🇳

Research Site, Vishakhapatnam, India

A Randomized, Open-label, Dose-ranging Study in Adults and Pediatric Individuals ≥ 12 Years of Age to Assess the Safety, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of AZD7442, for Pre-exposure Prophylaxis of COVID-19

Phase 2
Terminated
Conditions
Coronavirus Disease 2019 (COVID-19)
Interventions
First Posted Date
2022-05-17
Last Posted Date
2024-10-23
Lead Sponsor
AstraZeneca
Target Recruit Count
251
Registration Number
NCT05375760
Locations
🇺🇸

Research Site, Annandale, Virginia, United States

A Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)

First Posted Date
2022-05-16
Last Posted Date
2025-04-13
Lead Sponsor
AstraZeneca
Target Recruit Count
644
Registration Number
NCT05374512
Locations
🇬🇧

Research Site, Warwick, United Kingdom

Savolitinib Combine With Durvalumab in EGFR Wild-type Locally Advanced or Metastatic NSCLC

Phase 2
Active, not recruiting
Conditions
Lung Cancer
Interventions
First Posted Date
2022-05-16
Last Posted Date
2025-04-27
Lead Sponsor
AstraZeneca
Target Recruit Count
47
Registration Number
NCT05374603
Locations
🇨🇳

Research Site, Zhengzhou, China

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