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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

A Study to Investigate the Blood Concentrations of 4 Different Oral Doses of Zibotentan in Healthy Non-Asian and Japanese Participants

Phase 1
Completed
Conditions
Liver Cirrhosis
Interventions
First Posted Date
2024-12-04
Last Posted Date
2025-04-27
Lead Sponsor
AstraZeneca
Target Recruit Count
30
Registration Number
NCT06715670
Locations
🇺🇸

Research Site, Glendale, California, United States

AZD5305 hADME in Patients With Advanced Solid Malignancies

Phase 1
Recruiting
Conditions
Locally Advanced or Metastatic Solid Tumor
Interventions
Drug: Saruparib (AZD5305)
Drug: [14C]-AZD5305 microtracer
Drug: [14C]-AZD5305 (therapeutic dose)
First Posted Date
2024-12-03
Last Posted Date
2025-05-14
Lead Sponsor
AstraZeneca
Target Recruit Count
8
Registration Number
NCT06713369
Locations
🇬🇧

Research Site, Manchester, United Kingdom

Pooled Analysis of Single-arm Studies of Budesonide/Glycopyrronium/Formoterol (BGF) in Routine Care Setting

Recruiting
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
First Posted Date
2024-12-02
Last Posted Date
2025-05-21
Lead Sponsor
AstraZeneca
Target Recruit Count
2000
Registration Number
NCT06712563
Locations
🇬🇧

Research Site, London, United Kingdom

A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab

Phase 3
Recruiting
Conditions
Chronic Rhinosinusitis With Nasal Polyps
First Posted Date
2024-11-27
Last Posted Date
2025-05-22
Lead Sponsor
AstraZeneca
Target Recruit Count
180
Registration Number
NCT06706817
Locations
🇪🇸

Research Site, Santiago de Compostela, Spain

A Study to Investigate Multiple Ascending Doses of AZD5004 in Healthy Japanese Participants and Participants With Type 2 Diabetes Mellitus

Phase 1
Completed
Conditions
Healthy Participants
Type 2 Diabetes
Interventions
Drug: AZD5004(Part A)
Drug: Placebo(Part A)
Drug: AZD5004(Part B)
Drug: Placebo(Part B)
First Posted Date
2024-11-25
Last Posted Date
2025-03-21
Lead Sponsor
AstraZeneca
Target Recruit Count
35
Registration Number
NCT06703658
Locations
🇯🇵

Research Site, Osaka-shi, Japan

A Study in Patients With Myasthenia Gravis in China

Recruiting
Conditions
Myasthenia Gravis
First Posted Date
2024-11-22
Last Posted Date
2025-04-17
Lead Sponsor
AstraZeneca
Target Recruit Count
1200
Registration Number
NCT06700616
Locations
🇨🇳

Research Site, Wuhan, China

This Project Aims to Understand the Needs of Rheumatologists and Other Specialties in the Care of Patients With SLE

Completed
Conditions
Systemic Lupus Erythematosus
First Posted Date
2024-11-21
Last Posted Date
2025-01-14
Lead Sponsor
AstraZeneca
Target Recruit Count
1000
Registration Number
NCT06698900
Locations
🇧🇷

Research Site, Sao Paulo, Brazil

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

Phase 3
Recruiting
Conditions
Non-small Cell Lung Cancer
Interventions
First Posted Date
2024-11-18
Last Posted Date
2025-05-02
Lead Sponsor
AstraZeneca
Target Recruit Count
880
Registration Number
NCT06692738
Locations
🇻🇳

Research Site, Vinh, Vietnam

A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of AZD4144 in Participants With Severe Renal Impairment, End-stage Kidney Disease, and in Healthy Participants

Phase 1
Completed
Conditions
Renal Impairment
End-stage Kidney Disease
Healthy Participants
Interventions
First Posted Date
2024-11-18
Last Posted Date
2025-05-09
Lead Sponsor
AstraZeneca
Target Recruit Count
41
Registration Number
NCT06693765
Locations
🇷🇴

Research Site, Bucuresti, Romania

A Study to Assess the Effect of AZD0780 on Ambulatory Blood Pressure

Phase 2
Completed
Conditions
Atherosclerotic Cardiovascular Disease
Interventions
Drug: Placebo
First Posted Date
2024-11-18
Last Posted Date
2025-05-18
Lead Sponsor
AstraZeneca
Target Recruit Count
202
Registration Number
NCT06692764
Locations
🇺🇸

Research Site, Paris, Texas, United States

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